Bio-microelectromechanical systems

生物微机电系统

• 批准号: CRC-2021-00474
• 负责人: SanatiNezhad, Amir
• 金额: $ 1.82万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=755793
• 关键词: Bio; microelectromechanical; systems

My research program seeks to develop, test, and validate a new diagnostic technology platform for rapid disease diagnosis, wearable biosensing, and in-vivo gut-intestinal microbiome sampling that can be used for the next generation of digital health monitoring, accurate disease detection, and precision diagnostics. The technology platform relies on combining capillary microfluidics taking care of sample preparation and electrochemical biosensors for ultrasensitive detection of various bodily fluid markers. My research program focuses on the diagnosis and prognosis of brain injuries, cancer, and infectious diseases, wearable detection of human stress using human sweat and saliva biomarkers, and non-invasive and spatial sampling and detection of gut-intestinal microbiome diversity. The impact of my research is to improve the health and the quality of life of healthy people and patients, to reduce the cost of the healthcare system with accurate and personalized diagnosis and prognosis of patients, to provide an equitable diagnosis platform to serve remote populations, and to train the new generation of biomedical experts with interdisciplinary expertise in diagnostics, medical devices, and sensors.

我的研究项目旨在开发、测试和验证一种新的诊断技术平台，用于快速疾病诊断、可穿戴生物传感和体内肠道微生物组采样，可用于下一代数字健康监测、准确的疾病检测、和精确诊断。该技术平台依靠结合负责样品制备的毛细管微流体和用于超灵敏检测各种体液标记物的电化学生物传感器。我的研究项目侧重于脑损伤、癌症和传染病的诊断和预后，利用人体汗液和唾液生物标记物对人体压力进行可穿戴检测，以及肠道微生物组多样性的非侵入性空间采样和检测。我的研究的影响是改善健康人和患者的健康和生活质量，通过准确和个性化的患者诊断和预后来降低医疗保健系统的成本，提供公平的诊断平台来服务偏远人群，培养具有诊断、医疗设备和传感器跨学科专业知识的新一代生物医学专家。