Polymeric Biomaterials

高分子生物材料

• 批准号: CRC-2019-00202
• 负责人: Zhu, Julian
• 金额: $ 14.57万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=730680
• 关键词: Polymeric; Biomaterials

Biocompatibility is important for polymeric biomaterials used for biomedical and pharmaceutical applications in contact with the human body. To address this issue, we use natural compounds and green chemistry methods in the design, synthesis and tests of degradable polymers, stimuli-responsive materials, self-healing hydrogels. The polymers will be made and tested for use in soft and hard tissue engineering, drug delivery, biosensing and cell culture. We will develop green chemistry methods for the synthesis and modification of polymers using enzymes. The research is multi-disciplinary in nature and will provide an ideal training environment for young highly qualified personnel.

生物相容性对于用于与人体接触的生物医学和药物应用的聚合物生物材料很重要。为了解决这个问题，我们在设计，合成和测试中使用自然化合物和绿色化学方法，可降解聚合物，刺激性反应性材料，自我修复水凝胶。将制造和测试聚合物，以用于软组织工程，药物递送，生物传感和细胞培养。我们将开发使用酶合成和修饰聚合物的绿色化学方法。这项研究本质上是多学科的，将为年轻的高素质人员提供理想的培训环境。