Metal Organic Chemistry

金属有机化学

• 批准号: CRC-2016-00061
• 负责人: Crudden, Cathleen
• 金额: $ 14.57万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=694404
• 关键词: Metal; Organic; Chemistry

In 2014, Crudden demonstrated that organic molecules bearing a reactive carbon atom (N-heterocyclic carbenes, NHCs) make organic layers on metal surfaces with unprecedented stability. Prior to this, organic-to-metal contacts were made using 30 year old technology based on sulfur-containing molecules. Unlike sulfur-based molecular layers, NHC-based layers withstand unprecedented extremes of pH, heat and oxidation. In this proposal, Crudden will: generate novel NHC structures, NHC monolayers on other metals, and test these films in biosensing, corrosion resistance and micropatterning. Other aspects of her work involve novel, metal-free catalysts and catalytic methods for the production of chiral molecules with important biological properties.

2014 年，Crudden 证明，带有活性碳原子的有机分子（N-杂环卡宾，NHC）可以在金属表面形成具有前所未有稳定性的有机层。在此之前，有机物与金属的接触是使用已有 30 年历史的基于含硫分子的技术制成的。与硫基分子层不同，NHC 分子层能够承受前所未有的极端 pH 值、高温和氧化。在这项提案中，克鲁登将：在其他金属上生成新颖的 NHC 结构、NHC 单层，并测试这些薄膜的生物传感、耐腐蚀性和微图案化。 她工作的其他方面涉及新颖的无金属催化剂和催化方法，用于生产具有重要生物特性的手性分子。