Metal Organic Chemistry

金属有机化学

• 批准号: CRC-2016-00061
• 负责人: Crudden, Cathleen
• 金额: $ 14.57万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=648353
• 关键词: Metal; Organic; Chemistry

In 2014, Crudden demonstrated that organic molecules bearing a reactive carbon atom* (N-heterocyclic carbenes, NHCs) make organic layers on metal surfaces with unprecedented stability. Prior to this, organic-to-metal contacts were made using 30 year old technology based on sulfur-containing molecules. Unlike sulfur-based molecular layers, NHC-based layers withstand *unprecedented extremes of pH, heat and oxidation. In this proposal, Crudden will: generate novel *NHC structures, NHC monolayers on other metals, and test these films in biosensing, corrosion *resistance and micropatterning. Other aspects of her work involve novel, metal-free catalysts and *catalytic methods for the production of chiral molecules with important biological properties.

2014 年，Crudden 证明，带有活性碳原子*（N-杂环卡宾，NHC）的有机分子可以在金属表面形成具有前所未有稳定性的有机层。在此之前，有机物与金属的接触是使用已有 30 年历史的基于含硫分子的技术制成的。与硫基分子层不同，NHC 分子层可承受*前所未有的极端 pH 值、热量和氧化。在该提案中，Crudden 将：在其他金属上生成新颖的 *NHC 结构、NHC 单层，并测试这些薄膜的生物传感、耐腐蚀和微图案化。 她工作的其他方面涉及新颖的无金属催化剂和用于生产具有重要生物特性的手性分子的催化方法。