Innate immunity in teleosts

硬骨鱼的先天免疫

• 批准号: RGPIN-2016-06202
• 负责人: Lumsden, John
• 金额: $ 2.99万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=630553
• 关键词: Innate; immunity; teleosts

My research program and the studies outlined in the present short-term objectives are designed to better understand innate resistance of fish to infectious disease. Aquaculture is responsible for more than half of all fish protein consumed worldwide and infectious disease is an important cause of lost production. Aquaculture is a growth industry for Canada and will continue to expand and support Canadian jobs in the future. The cost-benefit ratio (relatively low cost per unit product) for fish health requires that we identify innate markers for resistance to infectious disease to provide enhanced survival, without heavy reliance on antimicrobials or expensive products. Two important diseases of rainbow trout (RT) are viral hemorrhagic septicemia virus (VHSV) and

我的研究计划和当前短期目标中概述的研究旨在更好地了解鱼类对传染病的先天抵抗力。水产养殖消耗了全球一半以上的鱼类蛋白质，而传染病是产量损失的一个重要原因。水产养殖是加拿大的一个增长型产业，未来将继续扩大和支持加拿大的就业机会。鱼类健康的成本效益比（单位产品相对较低的成本）要求我们识别抵抗传染病的先天标记，以提高生存率，而无需严重依赖抗菌药物或昂贵的产品。虹鳟鱼（RT）的两种重要疾病是病毒性出血性败血症病毒（VHSV）和