Atomic Force Microscopy System for Biomedical, Materials, and Environmental Research

用于生物医学、材料和环境研究的原子力显微镜系统

• 批准号: RTI-2017-00308
• 负责人: Kim, Keekyoung
• 金额: $ 10.67万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=616629
• 关键词: Atomic; Force; Microscopy; System; Biomedical

Atomic force microscopy system (AFM) is one of the leading-edge scientific research tools for imaging, measuring, and manipulating samples at the nanoscale level. Specimen information is acquired by scanning its surface with a piezoelectrically driven mechanical probe. The requested AFM will be the only one on the Okanagan campus and, as such, it will be made available to all researchers on the campus. In this proposal, we highlight some of the multidisciplinary research performed by a diverse group of faculty that will benefit from this equipment. The researchers collaborating for this piece of equipment are from the fields of biomedical engineering, electrical engineering, environmental engineering, mechanical engineering, materials engineering, and biophysics. Therefore, the new AFM system will support current and future research activities of at least seven research programs from UBC’s Okanagan campus. The AFM system is an essential tool on any University campus and especially in the Okanagan campus where we have a strong contingency of materials and bio/nanomaterials researchers. Since there is no AFM system on the Okanagan campus nor in any of the local colleges or research facilities nearby, the travel to other institutions to make measurements has imposed a significant cost of travel and research delay for the respective research programs. More specifically, the discovery grants and strategic projects led by the applicants are urgently dependent on the use of an AFM system on our campus. From a long term perspective, we have several collaboration opportunities with the emerging local industries on the characterization of new materials that can be pursued using the AFM. Further delays will possibly result in losing some of our potential collaborations and significant damage to research programs. The proposed AFM system will be located in the CFI funded Integrated Bio-Micro/Nanotechnology Laboratory in the Engineering Building. We expect that the instrument will initially be used for about 20 hours per week but grow to close to or exceeding 140 hrs per month by users across the campus as the campus learns of the capabilities of the AFM. Therefore, there will be serious impacts to the research programs of many faculties. This equipment will support interdisciplinary research for approximately 20 graduate and undergraduate students. All students who will be working with the AFM will be thoroughly trained in how the AFM works, how to operate the AFM and how to interpret the data from the AFM. This includes the theory behind the tests, instrument calibration, sample preparation, experimental design, and data analysis. The use of the AFM will enhance their training in microscopy and surface characterization techniques immensely and truly allow the expansion of their research skills.

原子力显微镜系统（AFM）是用于成像，测量和操纵样品在纳米级水平的领先科学研究工具之一。通过用压电驱动的机械探针扫描表面来获取样品信息。要求的AFM将是Okanagan校园中唯一的AFM，因此，它将向校园的所有研究人员提供。在此提案中，我们重点介绍了一群将从该设备中受益的各种各样的教师进行的一些多学科研究。为此设备合作的研究人员来自生物医学工程，电气工程，环境工程，机械工程，材料工程和生物物理学领域。因此，新的AFM系统将支持UBC Okanagan校园至少七个研究计划的当前和未来研究活动。 AFM系统是任何大学校园的重要工具，尤其是在Okanagan校园中，我们拥有材料和生物/纳米材料研究人员的强大意外情况。由于Okanagan校园或附近的任何当地大学或研究机构都没有AFM系统，因此前往其他机构进行测量的旅行对相关研究计划施加了巨大的旅行和研究延迟。更具体地说，由申请人领导的发现赠款和战略项目迫切取决于在我们校园内使用AFM系统。从长期的角度来看，我们与新兴的当地行业有几个合作机会，涉及可以使用AFM追求的新材料的表征。进一步的延迟可能会导致我们的一些潜在合作和对研究计划的重大损害。拟议的AFM系统将位于CFI资助的工程大楼中资助的综合生物 - 纳米技术实验室。我们预计，随着校园得知AFM的能力，整个校园的用户每月将使用该仪器每周约20个小时，但每月可以接近或超过140小时。因此，将对许多学院的研究计划产生严重影响。该设备将支持大约20名研究生和本科生的跨学科研究。所有将与AFM合作的学生将接受有关AFM的工作方式，如何操作AFM以及如何从AFM中解释数据的培训。这包括测试背后的理论，仪器校准，样品制备，实验设计和数据分析。 AFM的使用将增强其在显微镜和表面表征技术方面的训练，并真正允许扩大其研究技能。