Electrokinetic microfluidics

动电微流控

• 批准号: 155248-2009
• 负责人: Li, Dongqing
• 金额: $ 2.19万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=505018
• 关键词: Electrokinetic; microfluidics

A lab-on-a-chip (LOC) device is a microscale laboratory on a business-card-sized glass or plastic chip with a network of microchannels. Applying electrical fields along microchannels controls the liquid flow and other operations in the chip. These LOC devices can perform specialized functions as their room-sized counterparts, such as clinical diagnoses of bacteria infection and cancers. The key advantages include dramatically reduced sample and reagent consumption, high speed of analysis, automation and portability. Most biomedical analyses involve multiple biochemical and physical processes of molecules and cells in aqueous solutions. A LOC device therefore must integrate the functions of different bench-top instruments into a single chip, and can perform multiple, sequential microfluidic processes required for realizing the assays on a chip. In order to be able to systematically design LOC devices and control the chip operation precisely, one must understand the complicated microfluidic and nanofluidic phenomena and processes.

芯片实验室 ​​(LOC) 设备是一个位于名片大小的玻璃或塑料芯片上的微型实验室，具有微通道网络。沿着微通道施加电场可以控制芯片中的液体流动和其他操作。这些 LOC 设备可以像房间大小的设备一样执行特殊功能，例如细菌感染和癌症的临床诊断。主要优点包括显着减少样品和试剂消耗、高速分析、自动化和便携性。大多数生物医学分析涉及水溶液中分子和细胞的多种生化和物理过程。 因此，LOC 设备必须将不同台式仪器的功能集成到单个芯片中，并且可以执行在芯片上实现分析所需的多个连续微流体过程。 为了能够系统地设计LOC器件并精确控制芯片的运行，必须了解复杂的微流控和纳流控现象和过程。