Animal Core

动物核心

基本信息

批准号：
8874856
负责人：
Saverio Vincent Capuano
金额：
$ 52.31万
依托单位：
UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至 2016-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8874856
关键词：
AIDS vaccine development Accreditation Address Adult Alleles Animal Technicians Animals Applications Grants Attention Autopsy Behavioral Biological Biology Biomedical Research Biopsy Blood Caring Clinical Ensure Environment Equipment Funding Goals HIV Infections Health Housing Human Human Resources In Vitro Individual Infectious Agent Instruction Interleukin-12 International Laboratory Animals Macaca Macaca mulatta Medical Mission Modeling Pathologist Performance Personal Satisfaction Personnel Management Population Primates Procedures Quality of life Recombinant DNA Regulation Research Research Personnel Research Support SIV Sampling Schedule Scientist Services Training Universities Urine Veterinarians Well in self Wisconsin Work Yellow Fever animal care environmental enrichment for laboratory animals experience improved in vivo nonhuman primate programs psychologic research study skills vector

项目摘要

The Animal Services Division of the WNPRC employs a fully trained staff of veterinarians; veterinary technicians, veterinary pathologists, research technicians, enrichment technicians, and animal care technicians. These individuals, who provide the necessary medical care, daily husbandry, and environmental enrichment for a NHP population of almost 1500 and research support for greater than 95 local, regional, national, and international scientists will compose the Animal Core for the proposed HIVRAD nonhuman primate experiments. The six aims of this Core will be as follows: 1) To provide healthy, genetically characterized rhesus macaques for the projects outlined in this application. 2) To provide contemporary, well-equipped experimental facilities for the performance of the husbandry, clinical, experimental, and necropsy procedures outlined in this application. 3) To provide expert husbandry, veterinary, and technical assistance necessary to support and maintain the SIV infected animals utilized on this project. 4) To ensure compliance with all university and federal regulations regarding the use of NHP in biomedical research. 5) To provide the specialized environmental enrichment needed to maintain the psychological well being of the SIV infected macaques that will be utilized in the proposed projects. 6) To obtain quality biological samples from the experimental animals to fulfill the objectives of the individual projects.

WNPRC 动物服务部拥有训练有素的兽医人员；兽医技术人员、兽医病理学家、研究技术人员、浓缩技术人员和动物护理人员技术人员。这些人提供必要的医疗护理、日常饲养和为近 1500 名 NHP 人口提供环境富集，并为超过 95 名 NHP 人口提供研究支持地方、区域、国家和国际科学家将为拟议的 HIVRAD 组成动物核心非人类灵长类动物实验。该核心的六个目标如下： 1) 为上述项目提供健康的、具有基因特征的恒河猴这个应用程序。 2) 提供现代化、设备齐全的实验设施本申请中概述的畜牧、临床、实验和尸检程序。 3) 提供必要的专业畜牧、兽医和技术援助，以支持和维护本项目中使用的 SIV 感染动物。 4) 确保遵守所有大学和联邦有关 NHP 使用的法规生物医学研究。 5）提供维持心理所需的专门环境丰富将在拟议项目中使用的受 SIV 感染的猕猴的健康状况。 6）从实验动物中获取优质生物样本，以实现以下目标：个别项目。