Genomics of rapid adaptation in the lab and in the wild

实验室和野外快速适应的基因组学

• 批准号: 9071712
• 负责人: Dmitri Petrov
• 金额: $ 71.24万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2021-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9071712
• 关键词: Award; Biology; Communicable Diseases; Drosophila genus; Evolution; Funding Opportunities; Genomics; Grant; Heart; Humanities; Malignant Neoplasms; Mutation; Process; Research; Research Personnel; Series; System; Theoretical Studies; Yeasts; genomic data; public health relevance; theories

 DESCRIPTION (provided by applicant): Adaptation is the central concept in evolution and biology in general. I aim to build and quantitative and predictive theory of the adaptive process by focusing on interrelated empirical, computational, and theoretical studies of rapid adaptation in a range of systems. The MIRA grant will be supporting three specific umbrella projects that focus on: (i) inference of the dynamics of adaptation from genomic data, (ii) studies of rapid seasonal adaptation in Drosophila, and (iii) high throughput studies of adaptive mutation in experimental evolution studies in yeast.

 描述（应用程序提供）：适应是进化和生物学的中心概念。我的目标是通过关注一系列系统中快速适应的经验，计算和理论研究来构建和定量和预测理论。 MIRA Grant将支持三个专注于：（i）基因组数据适应动力学的三个特定伞项目，（ii）果蝇快速季节性适应性的研究以及（iii）酵母实验进化研究中自适应突变的高吞吐量研究。