The Boston NETT Group

波士顿NETT集团

• 批准号: 9088529
• 负责人: Joshua N Goldstein
• 金额: $ 30.23万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2018-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9088529
• 关键词: Academic Medical Centers; Accident and Emergency department; Achievement; Acute; Adult; Area; Award; Boston; Caring; Cities; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Unit; Data Quality; Disease; Doctor of Philosophy; Emergency Medicine; Emergency Situation; Emergency treatment; Enrollment; Funding; General Hospitals; Health; Hospitals; Human Resources; Institutes; Israel; Leadership; Massachusetts; Medical center; Meningitis; Morbidity - disease rate; Multicenter Trials; National Institute of Neurological Disorders and Stroke; Neurological emergencies; Neurology; Patient Care; Patients; Pediatric Hospitals; Performance; Population; Positioning Attribute; Principal Investigator; Protocols documentation; Provider; Recording of previous events; Records; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Seizures; Services; Site; Source; Spinal cord injury; Stroke; System; Therapeutic Trials; Time; Translational Research; Traumatic Brain Injury; Vision; Woman; acute stroke; catalyst; clinical research site; data management; design; disability; improved; innovation; meetings; metropolitan; mortality; nervous system disorder; programs; skills; success; trauma centers; treatment trial

DESCRIPTION (provided by applicant): We propose to create the Boston NETT Site, a team of hospitals and EMS agencies in Boston that will serve as a top-enrolling site and vibrant contributor to the NETT Network. Our group includes all adult Level I trauma centers in the city of Boston. All hospitals have a proven track record of successful management and performance of clinical trials. In particular, all hospitals have an established research infrastructure that performs ongoing clinical research in both emergency and neurology departments, which can be leveraged to meet the needs of NETT. Principal investigator Joshua N. Goldstein, MD, PhD, and Co-investigator Jonathan Rosand, MD, MS bring a complementary set of skills in managing successful clinical research programs, membership on Steering Committees, and positions of national leadership in their fields. Our team includes investigators in neurology and emergency medicine with nationally recognized expertise managing the difficult task of enrolling patients in the emergency setting. Strengths of the Boston NETT Group include 1) the close personal and professional ties between multiple investigators, as shown by a history of successful collaborative research projects; 2) a large population from a major metropolitan area that spans the full range of neurologic disorders; 3) talented teams of site Investigators with track records of scientific achievement and innovation, as well as subject recruitment and data management in multicenter trials; 4) an existing research infrastructure, funded by a range of sources including NINDS, which can be leveraged to meet the needs of NETT; 5) numerous existing clinical research programs including the Neurology Clinical Trials Unit, The Harvard Catalyst Clinical and Translational Science Award (CTSA) program, the BU Clinical and Translational Science (CTSA) Institute, the Specialized Programs of Translational Research in Acute Stroke (SPOTRIAS) Network, the NeuroNEXT Network, and the NeuroNEXT Clinical Coordinating Center; 6) close integration with pre-hospital services, including Boston EMS and Boston Medflight. Overall, the Boston NETT Group has the resources, vision, and enthusiasm to enhance the ongoing success of the NETT Network.

描述（由申请人提供）：我们建议创建波士顿Nett网站，波士顿的医院和EMS机构团队将充当顶级入门网站，并为Nett Network提供了充满活力的贡献者。我们的小组包括波士顿市的所有成人I级创伤中心。所有医院都有成功的临床试验管理和性能的可靠记录。特别是，所有医院都有既定的研究基础设施，该基础设施在紧急和神经病学部门都进行了持续的临床研究，可以利用这些研究来满足Nett的需求。首席研究员Joshua N. Goldstein，医学博士，博士和MS医学博士Jonathan Rosand的共同投资者乔纳森·罗森（Jonathan Rosand）带来了一套互补的技能，以管理成功的临床研究计划，指导委员会的会员资格以及在其领域的国家领导地位。我们的团队包括神经病学和急诊医学的研究人员，拥有全国认可的专业知识，该专业知识管理急诊室的艰巨任务。波士顿Nett小组的优势包括1）多个调查人员之间的个人和专业关系，如成功的协作研究项目的历史所示； 2）来自主要大都市地区的大量人口跨越了整个神经系统疾病； 3）有才华的现场调查员团队，具有科学成就和创新的记录，以及多中心试验中的主题招聘和数据管理； 4）现有的研究基础设施，由包括NIND在内的一系列来源资助，可以利用这些来源来满足Nett的需求； 5）许多现有的临床研究计划，包括神经病学临床试验部门，哈佛催化剂临床和转化科学奖（CTSA）计划，BU临床和转化科学（CTSA）研究所，急性中风转化研究专业计划（SpotRias）网络，Neuronext网络和Neuronext临床协调中心； 6）与院前服务的密切集成，包括波士顿EMS和波士顿Medflight。总体而言，波士顿Nett集团具有增强NetT网络成功的资源，愿景和热情。