Center for Advanced Imaging Innovation and Research (CAI2R)

先进成像创新与研究中心 (CAI2R)

• 批准号: 9110718
• 负责人: Daniel K Sodickson
• 金额: $ 115.87万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-30 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9110718
• 关键词: Address; Affect; Area; Caring; Clinical; Clinical Research; Collaborations; Complex; Data; Degenerative polyarthritis; Development; Diagnosis; Disease; Engineering; Feedback; Glean; Goals; Image; Imaging Device; Imaging Techniques; Imaging technology; Indolent; Industry; Instruction; Joint repair; Knowledge; Magnetic Resonance Imaging; Malignant Neoplasms; Malignant neoplasm of prostate; Metabolic; Modeling; Molecular; Musculoskeletal Diseases; Neurologic; Patient Care; Patients; Performance; Physicians; Positron-Emission Tomography; Protocols documentation; Public Health; Reading; Research; Role; Route; Safety; Scanning; Scientist; Services; Shapes; Techniques; Technology; Technology Assessment; Time; Training; Training Activity; Translating; Translational Research; Vendor; Visit; academic standard; clinical practice; data acquisition; design; flexibility; image reconstruction; imaging modality; improved; industry partner; innovation; interdisciplinary collaboration; joint injury; malignant breast neoplasm; multimodality; musculoskeletal imaging; nervous system disorder; neuroimaging; new technology; novel; operation; public health relevance; radiofrequency; rapid technique; reconstruction; research and development; symposium; technology development; technology/technique; time use; tool

DESCRIPTION: The Center for Advanced Imaging Innovation and Research (CAI2R) combines three areas of novel and high-impact imaging technology development with a unique new model for interdepartmental and academic-industrial collaboration aimed at translating that technology rapidly and effectively into clinical practice. The technologies to be developed center around a new paradigm of rapid, continuous, and comprehensive data acquisition, together with flexible image reconstruction, which will affect and connect multiple imaging modalities, including magnetic resonance imaging (MRI) and Positron Emission Tomography (PET). Technology Research and Development (TR&D) project #1 aims at a new use of time in imaging, deploying leading-edge methods of rapid image acquisition and advanced image reconstruction to replace traditional complex, targeted, and inefficient imaging protocols with simple, comprehensive, volumetric acquisitions that contain rich information about multiple complementary contrasts and diverse dynamics. TR&D #2 envisions new and improved uses for radiofrequency (RF) fields, providing new tools for RF design, safety and control in MRI, and expanding the reach of the rapid continuous acquisition approach developed in TR&D #1 to high-performance high-field applications. TR&D #3 is addressed at new uses of simultaneity, advancing the fundamental capabilities of MR and PET through synergistic simultaneous acquisition and joint reconstruction. Our Center has a unique and explicit translational focus, which is reflected in the day-to-day operation of TR&D projects as well as in the topics of Collaborative Projects (CPs) and Service Projects (SPs), which are focused on three general areas of high public health impact: cancer, musculoskeletal disease, and neurologic disease. In keeping with this translational emphasis, CAI2R is also be driven by a novel collaboration model in which basic scientists, clinicians, and industry developers sit down together regularly at the scanners and in reading rooms for interactive technology development and assessment. This interdisciplinary collaboration model also informs our Training activities, many of which are addressed at the formation and operation of successful translational research teams. Meanwhile, with early involvement of clinical stakeholders and industry partners, we aim to make CAI2R technologies widely available for clinical and research use. Our broadest goal in CAI2R is to change the paradigms of data acquisition, image reconstruction, and day-to-day scanning for MR and PET, for the advancement of biomedical knowledge and for the benefit of patients and the physicians who care for them.

描述：高级成像创新与研究中心（CAI2R）将新颖和高影响成像技术开发的三个领域与一个独特的新模型，用于跨部门和学术工业合作的独特新模型，旨在将技术迅速有效地转化为临床实践。将开发的技术围绕着快速，连续和全面的数据采集的新范式，以及灵活的图像重建，这将影响和连接多种成像方式，包括磁共振成像（MRI）和Potitron发射断层扫描（PET）。技术研发（TR＆D）项目＃1旨在在成像中进行新的时间使用，以快速获取图像获取的领先方法和高级图像重建方法，以替代传统的复杂，有针对性和效率低下的成像协议，并具有简单，全面，大量的，以包含有关多种互补造成偶然和多样性动力学的丰富信息。 TR＆D＃2设想了射频（RF）字段的新用途和改进的用途，为MRI中的RF设计，安全性和控制提供了新的工具，并扩大了TR＆D 1中快速连续获取方法的覆盖范围。 TR＆D＃3是通过同时发生的新用途来解决的，通过同时收购和联合重建来推动MR和PET的基本能力。我们的中心具有独特而明确的翻译重点，这反映在TR＆D项目的日常运营以及协作项目（CPS）和服务项目（SPS）的主题中，该项目侧重于高公共健康影响的三个一般领域：癌症，肌肉骨骼疾病，肌肉疾病和神经疾病。 为了遵守这种翻译的重点，CAI2R也是由一种新颖的合作模型驱动的，基础科学家，临床医生和行业开发人员会定期坐在一起 扫描仪和阅读室进行交互式技术开发和评估。这种跨学科的合作模型还为我们的培训活动提供了信息，其中许多活动在成功的转化研究团队的组建和运作中得到了解决。同时，随着临床利益相关者和行业合作伙伴的早期参与，我们的目标是使CAI2R技术广泛可用于临床和研究。我们在CAI2R中最广泛的目标是改变MR和PET的数据获取，图像重建和日常扫描的范例，以促进生物医学知识的发展，并为患者和照顾他们的医生的利益而受益。