Transdisciplinary Training in Sleep and Circadian Rhythms

睡眠和昼夜节律的跨学科培训

• 批准号: 10576970
• 负责人: Kenneth P Wright
• 金额: $ 25.96万
• 依托单位: UNIVERSITY OF COLORADO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10576970
• 关键词: Circadian Rhythms; Sleep; Training

ABSTRACT The primary aim of this new University of Colorado transdisciplinary training program is to prepare outstanding pre-(PhD) and post-(PhD, MD/PhD, MD) doctoral fellows for science careers that address cutting-edge basic and clinical research questions that represent the future of biomedical research. The training program will foster transdisciplinary research with state-of-the-art technologies and methods used by participating faculty laboratories, and will evaluate and enhance the mentoring skills of early career faculty. The program is novel in that it exposes trainees and faculty from diverse biomedical research backgrounds to collaborative sleep and circadian science. Similarly, current sleep and circadian trainees and expert faculty benefit from meaningful interactions with investigators from different research backgrounds, particularly those from biomedical research areas that are of high importance to the NIH/NHLBI. The research training activities of the 22 participating faculty emphasize transdisciplinary training in sleep and circadian physiology with research programs focused on cardiovascular, genetics/genomics, metabolomics, proteomics, biomarker development, bioinformatics, biostatistics, epidemiology, stress physiology, immunology, endocrinology, metabolism, obesity, diabetes, neuroscience, pediatrics, development, aging, psychiatry, and pulmonary and behavioral sleep medicine. Because our goal is to provide transdisciplinary and translational research career training, major program components of this T32 include the Department of Integrative Physiology, the Department of Psychology and Neuroscience, and the Institute for Behavioral Genetics at University of Colorado Boulder, and multiple clinical departments and divisions at University of Colorado School of Medicine Anschutz Medical Campus. The existing fruitful and collaborative environment is a strength of this training grant. Of the existing T32s at the University of Colorado, this would be the only one dedicated to transdisciplinary sleep and circadian science. Also, it would become the first sleep and circadian T32 in the Western United States. The specific aims of the training program are to recruit, select and retain outstanding trainees; promote inclusive excellence; provide high quality training, educational, and career development experiences to prepare trainees for research-intensive and research-related careers; shape tomorrow’s scientific leaders; foster rigorous and collaborative sleep and circadian science; ensure successful progress of trainees toward predetermined milestones defined in Individual Development Plans; enhance the mentoring skills of faculty through a formal mentoring training plan; ensure conscientious program evaluation; and expand the number of investigators conducting transdisciplinary sleep and circadian science. We request support for one pre-doctoral and one post-doctoral trainee in year 1, and two pre-doctoral and two post-doctoral trainees in years 2-5.

抽象的 科罗拉多大学这个新的跨学科培训计划的主要目的是培养杰出的 博士前（PhD）和博士后（PhD、MD/PhD、MD）博士研究员，从事科学职业，解决前沿基础问题 以及代表生物医学研究未来的临床研究问题。 利用参与教师使用的最先进的技术和方法促进跨学科研究 实验室，并将评估和提高早期职业教师的指导技能。该计划在以下方面是新颖的。 它让来自不同生物医学研究背景的学员和教师接触到协作睡眠和 同样，当前的睡眠和昼夜节律学员和专家教师也受益于有意义的研究。 与来自不同研究背景的研究人员互动，特别是来自生物医学研究的研究人员 对 NIH/NHLBI 高度重要的领域 22 个参与项目的研究培训活动。 教师强调睡眠和昼夜生理学方面的跨学科培训，并以研究项目为重点 心血管、遗传学/基因组学、代谢组学、蛋白质组学、生物标志物开发、生物信息学、 生物统计学、流行病学、应激生理学、免疫学、内分泌学、新陈代谢、肥胖、糖尿病、 神经科学、儿科、发育、衰老、精神病学、肺和行为睡眠医学。 因为我们的目标是提供跨学科和转化研究职业培训、重大项目 该 T32 的组成部分包括综合生理学系、心理学系和 神经科学、科罗拉多大学博尔德分校行为遗传学研究所以及多个临床 科罗拉多大学医学院安舒茨医学校区的院系和部门。 现有的富有成效的协作环境是该培训补助金的一个优势。 科罗拉多大学，这将是唯一一所致力于跨学科睡眠和昼夜节律科学的大学。 此外，它将成为美国西部第一个睡眠和昼夜节律 T32。 培训计划的具体目的是招募、选拔和留住优秀的学员； 包容性卓越；提供高质量的培训、教育和职业发展经验，做好准备 研究密集型和研究相关职业的实习生；培养未来的科学领导者； 严格且协作的睡眠和昼夜节律科学，确保学员取得成功 个人发展计划中规定的预定里程碑提高教师的指导技能； 通过正式的指导培训计划；确保认真的计划评估并扩大培训的数量； 我们请求对一名博士前研究人员进行跨学科睡眠和昼夜节律科学研究的支持。 第一年有一名博士后实习生，第二年至第五年有两名博士前实习生和两名博士后实习生。