P30- Core Grant for Vision Research

P30-视觉研究核心资助

基本信息

批准号：
7805452
负责人：
HENRY Francis EDELHAUSER
金额：
$ 61.52万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-04-01 至 2011-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7805452
关键词：
Amino Acid Sequence Anatomy Applications Grants Basic Science Bioinformatics Biometry Caliber Cancer Center Support Grant Cellular biology Center Core Grants Centers for Disease Control and Prevention (U.S.)Clinical Clinical Sciences Collaborations Computer Analysis Confocal Microscopy Core Facility Dermatology Discipline Electron Microscopy Eye Faculty Fellowship Flow Cytometry Fostering Funding Gene Expression Grant Image Image Analysis Immunohistochemistry In Vitro Individual Institutes Lasers Light Magnetic Resonance Imaging Medical center Neurology Oligonucleotides Ophthalmology Peptide Sequence Determination Pharmacology Postdoctoral Fellow Primates Principal Investigator Productivity Proteomics Psychology Publications Research Research Project Grants Resources Role Services Technology Training United States Department of Veterans Affairs Universities Vision research base data management eye center functional genomics in vivo medical schools pre-doctoral ranpirnase research facility structural biology

项目摘要

DESCRIPTION (provided by applicant): Continued support is requested for the NEI Core Center Grant in the Department of Ophthalmology at Emory University. This Core Center Grant renewal application includes three Modules: (1) Structural Biology and Imaging, (2) Functional Genomics and Proteomics, and (3) Bioinformatics and Biostatistics. The past Core Center grant has successfully utilized supporting collaborative vision research and service involving 32 faculty (including more than 21 NEI funded principal investigators), 16 postdoctoral fellows, six predoctoral fellows and generating over 250 publications over the past five years. The Structural Biology and Imaging Module adds immunohistochemistry, in vivo and in vitro confocal microscopy, fluoresence image analysis, in vivio flurophotomery and magnetic resonance image to the light and electron microscopy services. The Functional Genomics and Proteomics module provides services for synthetic oligonucleotides, protein sequences, PCR, laser microcapture with gene expression and flow cytometry. The Bioinformatics and Biostatistics Module will provide integrated biostatistics, bioinformatics and data management in advanced computational analysis and bioinformatics resources. The Core Modules have and will continue to enhance our research productivity by providing common centralized services to stimulate and facilitate collaborative studies between faculty an to attract other university disciplines to vision research. This Core facility also serves as a centralized vision research facility in Atlanta where faculty from Emory University, Yerkes Regional Primate Center, Georgia Institute of Technology, Georgia State University, Morehouse School of Medicine, The Veterans Administration Medical Center and the Centers for Disease Control and Prevention can undertake collaborative studies in vision research. The Core facilities also serve a role in the research projects of our pre- and postdoctoral fellows supported by our departmental NEI Training Grant (T32 EY007092-19), recently renewed for the next five years (2004-2009).

描述（由申请人提供）：埃默里大学眼科部门的NEI Core Center Grant要求持续支持。此核心中心授予的续签应用包括三个模块：（1）结构生物学和成像，（2）功能基因组学和蛋白质组学以及（3）生物信息学和生物统计学。过去的Core Center Grant已成功地利用了涉及32位教职员工（包括21多名NEI资助的首席研究人员），16名博士后研究员，6名托管前研究员，并在过去五年中产生250多个出版物的协作愿景研究和服务。结构生物学和成像模块在体内和体外共聚焦显微镜，荧光图像分析，体内氟温体体和磁共振图像中添加了免疫组织化学，并为光和电子显微镜服务增加。功能性基因组学和蛋白质组学模块为合成寡核苷酸，蛋白质序列，PCR，激光微接管提供基因表达和流式细胞术的服务。生物信息学和生物统计学模块将在高级计算分析和生物信息学资源中提供综合的生物统计学，生物信息学和数据管理。核心模块拥有并将继续通过提供共同的集中式服务来刺激和促进教师之间的协作研究，以吸引其他大学学科进行视觉研究，从而继续提高我们的研究生产率。该核心设施还作为亚特兰大的集中式视觉研究机构，来自埃默里大学，耶克斯地区灵长类动物中心，佐治亚州理工学院，乔治亚州立大学，莫尔豪斯医学院，退伍军人管理局，医疗中心和疾病控制中心的教师可以在视觉研究中进行协作。核心设施在我们的部门NEI培训补助金（T32 EY007092-19）支持的我们的前和博士后研究员的研究项目中也发挥了作用，该培训拨款最近在未来五年（2004-2009）续签。