Administrative Core

行政核心

• 批准号: 10252022
• 负责人: MARCIA Roxana CRUZ-CORREA
• 金额: $ 45.3万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-02 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10252022
• 关键词: Achievement; Address; Advisory Committees; Affect; Area; Basic Science; Cardiometabolic Disease; Caribbean Hispanic; Caring; Clinical; Clinical Research; Communicable Diseases; Communication; Communities; Community Health; Development; Disasters; Disease; Emerging Communicable Diseases; Ensure; Evaluation; Foundations; Funding; Goals; Government Agencies; Health; Health Sciences; Healthcare; Hispanics; Hospitals; Infrastructure; Institution; Island; Lead; Leadership; Malignant Neoplasms; Medical; Modeling; Monitor; Policies; Population; Positioning Attribute; Procedures; Productivity; Puerto Rico; Research; Research Infrastructure; Research Institute; Research Personnel; Resources; Science; Services; Structure; Supervision; Support System; Time; Translating; Translational Research; United States National Institutes of Health; Universities; authority; base; clinical development; collaboratory; cost effective; cost efficient; design; experience; flexibility; improved; innovation; medical schools; medically underserved; medically underserved population; multidisciplinary; operation; organizational structure; outreach; programs; skills; tool

ABSTRAC- ADMINISTRATIVE CORE There is a need for well-coordinated infrastructure, multi-institutional and multidisciplinary collaborative networks that target specific populations and facilitate high-quality, cost-efficient and regulatory compliant research and health care strategies. The Hispanic Alliance for Clinical and Translational Research (the Alliance) will integrate clinical and translational research infrastructure and resources across a predominantly Hispanic U.S. jurisdiction to bridge the gaps between basic and clinical translational research, to address severe health conditions that disproportionately affect the medically underserved, and highly prevalent among Hispanic populations. The long-term goal of the Administrative Core of the Alliance is to provide a model for the optimal management and development clinical and translational research infrastructure in resource-limited settings that provide care to medically underserved populations. The specific objective of the Administrative Core will be to establish a leadership and management structure that will ensure that the Alliance KCA’s and milestones are met effectively and efficiently and when necessary realign the existing institutional and Alliance resources. This will be accomplished through three specific aims: 1) Provide an integrated organizational structure, leadership and advisory support system to effectively supervise, manage and monitor progress of all the Alliance key component activities/cores leading to achievement of the proposed milestones; 2) Develop and implement policies, procedures, and practices that ensure efficiency, sustainability, and scientific and fiscal flexibility to accommodate the changing needs and priorities of the Investigators, leading to new innovative and competitive areas of clinical and translational research; 3) Provide timely financial, dissemination, communication and evaluation functions that promote expansion of innovative clinical and translational research and services and long-term sustainability of the Alliance. The proposed administrative structure will bring together key leaders from the participating Institutions and external collaborators, further developing a pre-existing collaborative structure that has been successful in obtaining external funding and developing early-stage investigators. It will provide an efficient and integrated governance and administrative structure that will ensure the optimal and cost-effective utilization of resources. This will ultimately lead to successful advances in Clinical and Translational research in prevalent conditions in our population.

摘要-管理核心 需要协调良好的基础设施、多机构和多学科 针对特定人群并促进高质量、具有成本效益和 符合法规的研究和医疗保健策略。 转化研究（联盟）将整合临床和转化研究 跨越以西班牙裔为主的美国司法管辖区的基础设施和资源，以弥合差距 基础和临床转化研究之间的合作，以解决严重的健康问题 对医疗服务不足的人造成不成比例的影响，并且在西班牙裔中非常普遍 联盟行政核心的长期目标是提供一个模型。 用于优化管理和开发临床和转化研究基础设施 资源有限的环境，为医疗服务不足的人群提供护理。 行政核心的目标是建立领导和管理结构 这将确保有效且高效地实现联盟 KCA 和里程碑 必要时重新调整现有的机构和联盟资源。 通过三个具体目标来实现：1）提供一个综合的组织结构， 有效监督、管理和监控进展的领导和咨询支持系统 导致实现拟议目标的所有联盟关键组成部分活动/核心 里程碑；2）制定和实施确保效率的政策、程序和实践， 可持续性以及科学和财政灵活性，以适应不断变化的需求和优先事项 研究人员的努力，导致临床和转化的新的创新和竞争领域 研究；3) 提供及时的财务、传播、沟通和评估功能， 促进创新临床和转化研究与服务的扩展以及长期 拟议的管理结构将汇集主要领导人。 来自参与机构和外部合作者的意见，进一步发展了现有的 已成功获得外部资金和开发的合作结构 它将提供高效、综合的治理和行政管理。 的结构将确保资源的最佳和具有成本效益的利用。 导致我们在普遍情况下的临床和转化研究取得成功进展 人口。