Career Development for Genomic/Genetic Studies in Lung Diseases

肺部疾病基因组/遗传学研究的职业发展

基本信息

批准号：
7903383
负责人：
Allan I Pack
金额：
$ 39.96万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-27 至 2013-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7903383
关键词：
Area Arts Asthma Award Bioinformatics Chronic Obstructive Airway Disease Clinical Oncology Supplement (K12)Clinical and Translational Science Awards Complex Critical Care Disease Doctor of Philosophy Educational Curriculum Faculty Funding Future Genetic Genomics Hypersensitivity Individual Institutes Joints Laboratories Lung Lung Transplantation Lung diseases Malignant neoplasm of lung Mentors Neurobiology Obstructive Sleep Apnea Pediatric Hospitals Pennsylvania Philadelphia Physicians Principal Investigator Research Research Project Grants Resources Rotation Sampling Sarcoidosis Scientist Sleep Training Translational Research Universities University Hospitals abstracting base career development design experience flexibility genetic analysis genetic epidemiology interstitial medical schools patient population programs respiratory trait translational medicine

项目摘要

DESCRIPTION (provided by applicant): This proposal outlines a program to train physician scientists and Ph.D. scientists in genetic/genomic approaches to lung disease. The program builds on the substantial resources in this area at the University of Pennsylvania (Penn). These include the following: the recently established Center for Applied Genomics; the recently established Center for Genetic Analysis of Complex Traits; the Penn Genomics Institute; Penn Center for Bioinformatics; Institute for Translational Medicine; the recently funded Clinical and Translational Science Award; the Center for Sleep and Respiratory Neurobiology; the vibrant research programs of the Pulmonary, Allergy and Critical Care Division at the Hospital of the University of Pennsylvania; and the Pulmonary Division at the Children's Hospital of Philadelphia. The program is a joint one between the School of Medicine at Penn and the Children's Hospital of Philadelphia. The program is directed by an Executive Committee of Dr. Allan Pack (Principal Investigator), Dr. Steven Albelda, Dr. Jason Christie and Dr. Hakon Hakonarson. Faculty involved have expertise in a variety of lung diseases (obstructive sleep apnea, asthma, COPD, interstitial disease, lung cancer, sarcoidosis, lung transplantation) and for many of these diseases there are already DMA samples in a large well characterized patient populations facilitating the research of the trainees. The faculty also include individuals with methodological expertise from the areas of bioinfomatics, genetic epidemiology and statistical genetics. The proposed program for each trainee is flexible and will be based on the trainee's previous educational experience. It will involve a core curriculum of courses, elective courses, laboratory rotations and a mentored research project. A new specific track for genetic/genomic approaches is being established as part of the recently created Master's in Translational Research program. It is envisaged that during the support provided by this K12 award, trainees would apply for their own K/R award. The program is designed to be state of the art and to train the diverse scientific workforce that is required for the interdisciplinary teams of the future. (End of Abstract)

描述（由申请人提供）：该提案概述了培训医师科学家和博士学位的计划。遗传/基因组疾病方法的科学家。该计划基于宾夕法尼亚大学（Penn）的该领域的大量资源。其中包括以下内容：最近建立的应用基因组学中心；最近建立的复杂性状遗传分析中心；宾夕法尼亚州基因组学院；宾夕法尼亚州生物信息学中心；翻译医学研究所；最近资助的临床和转化科学奖；睡眠和呼吸神经生物学中心；宾夕法尼亚大学医院的肺，过敏和重症监护室的充满活力的研究计划；以及费城儿童医院的肺部。该计划是宾夕法尼亚州医学院和费城儿童医院之间的联合计划。该计划由Allan Pack博士（首席研究员），Steven Albelda博士，Jason Christie博士和Hakon Hakonarson博士的执行委员会执行。所涉及的教师在多种肺部疾病（阻塞性睡眠呼吸暂停，哮喘，COPD，间质疾病，肺癌，结节病，肺移植）方面具有专业知识，对于许多这些疾病，已经有很多DMA样本中有良好表征的患者人群，促进了受训者的研究。该学院还包括具有生物启动学，遗传流行病学和统计遗传学领域的方法论专业知识的人。每个学员的拟议计划都是灵活的，将基于学员以前的教育经验。它将涉及课程，选修课程，实验室轮换和指导研究项目的核心课程。作为最近创建的转化研究硕士的一部分，正在建立一种新的遗传/基因组方法的特定轨道。可以预见的是，在该K12奖励提供的支持期间，学员将申请自己的K/R奖。该计划旨在成为艺术的状态，并培训未来跨学科团队所需的多样化科学劳动力。（抽象的结尾）