GENETICS OF WHITE MATTER DEFICITS IN SCHIZOPHRENIA

精神分裂症白质缺陷的遗传学

• 批准号: 8167249
• 负责人: PHILIP R SZESZKO
• 金额: $ 3.86万
• 依托单位: FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167249
• 关键词: Brain; Computer Retrieval of Information on Scientific Projects Database; Data; Databases; Funding; Genes; Genetic; Genetic Variation; Grant; Individual; Institution; Magnetic Resonance Imaging; Measures; Mental disorders; Patients; Protocols documentation; Research; Research Ethics Committees; Research Personnel; Resources; Schizophrenia; Source; Structure; United States National Institutes of Health; healthy volunteer; in vivo; white matter

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The aim of this study is to examine the relationship between genetic variation and measures of brain structure and function in individuals with psychiatric disorders and healthy volunteers. In particular, we will determine the relationship between genes associated with white matter structure and in-vivo measures of brain white matter integrity in patients with schizophrenia and healthy volunteers. Archival data will be obtained through the IRB-approved protocol entitled "Data repository for Magnetic Resonance Imaging (MRI) Scans of Psychiatric Patients and Healthy Volunteers."

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究的目的是检查精神疾病患者和健康志愿者的遗传变异与大脑结构和功能量度之间的关系。 特别是，我们将确定精神分裂症患者和健康志愿者患者中与白质结构与脑白质完整性相关的基因之间的关系。 档案数据将通过IRB批准的协议获得，标题为“用于精神病患者和健康志愿者的磁共振成像（MRI）扫描的数据存储库”。