Administrative Core

行政核心

• 批准号: 10019355
• 负责人: Hermine I Brunner
• 金额: $ 20.83万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-16 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10019355
• 关键词: Adolescent; Advisory Committees; Affect; Child; Childhood; Chronic Childhood Arthritis; Clinical; Clinical Research; Collaborations; Communication; Communities; Consultations; Development; Diagnosis; Disease; Doctor of Philosophy; Documentation; Education; Educational workshop; Ensure; Environment; Evaluation; Event; Expenditure; Family; Feasibility Studies; Fibromyalgia; Fostering; Funding; Goals; Health; International; Intervention; Intervention Trial; Label; Lead; Leadership; Medicine; Mentors; Mentorship; Methodology; Methods; Monitor; Musculoskeletal; Musculoskeletal Diseases; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Outcome; Outcome Measure; Parents; Patients; Pediatric Hospitals; Pediatric Research; Pharmaceutical Preparations; Pilot Projects; Prevention; Process; Progress Reports; Research; Research Personnel; Resources; Rheumatology; Role; Science; Scientist; Services; Systemic Lupus Erythematosus; Testing; United States National Institutes of Health; Universities; Work; career; clinical center; college; improved; improved outcome; innovation; lectures; member; novel; operation; outreach program; precision medicine; programs; skin disorder; symposium; synergism

ABSTRACT – ADMINISTRATIVE CORE The primary objective of this Core Center for Clinical Research is to promote impactful research in pediatric rheumatic and non-inflammatory musculoskeletal diseases (PMSKD) by the local and national Research Community with a focus on enhancing our well-established research programs and institutional expertise in juvenile idiopathic arthritis (JIA), childhood-onset systemic lupus erythematosus (cSLE) and juvenile-onset fibromyalgia (JFM). The role of the Administrative Core (AC) is to serve as the executive, coordinating and oversight component of the Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO) to enhance clinical research in PMSKD. The proposed Director is Hermine I Brunner, MD MSc MBA, and the Associate Director is Susmita Kashikar-Zuck, PhD, both well-established and senior clinical researchers. The chief executive & administrative body of PORTICO will be a 7-member Executive Committee (EC) composed of Drs. Brunner and Kashikar-Zuck and 5 highly accomplished scientists who will serve as the Director and Associate Director/s of the Methodology Core & Patient Assessment Resource Core. The EC will be supported by an Internal Advisory Committee, External Advisory Committee and Pilot and Feasibility study committee. The specific aims of the AC are (1) Provision of executive and scientific leadership for the efficient conduct and dissemination of innovative team science in PMSKD, (2) Development of an Outreach Program to promote interdisciplinary clinical research in PMSKD locally and nationally and (3) Provision of opportunities to test new ideas by creating and managing a Pilot & Feasibility Studies Program to fortify the goals of PORTICO. The AC will be responsible for focusing PORTICOs services, innovation and educational offerings to be complementary to those that already exist within the rich research environment within Cincinnati Children's Hospital and the University of Cincinnati College of Medicine and national resources and research networks to which the AC leadership is well connected. For the AC, we have developed a robust leadership plan, along with plans for communication, management and evaluation of the activities and resources of PORTICO. In addition, the AC will manage the outreach program, work to enhance the research community to support novel and innovative work by established and early career investigators to advance the field of PMSKD research.

摘要 – 行政核心 该临床研究核心中心的主要目标是促进有影响力的研究 局部和非炎症性肌肉骨骼疾病 (PMSKD) 国家研究社区，重点是加强我们完善的研究项目 幼年特发性关节炎 (JIA)、儿童期发病的系统性狼疮方面的机构专业知识 红斑狼疮 (cSLE) 和青少年发病的纤维肌痛 (JFM) 的作用。 核心（AC）是儿科的执行、协调和监督组成部分 肌肉骨骼和风湿病学创新核心中心（PORTICO）加强临床 PMSKD 研究的拟任主任是 Hermine I Brunner，医学博士、硕士、MBA 和 副主任是 Susmita Kashikar-Zuck 博士，他是一位资深的临床专家 PORTICO 的首席执行官和行政机构将由 7 名成员组成。 执行委员会（EC）由 Brunner 博士和 Kashikar-Zuck 博士以及 5 名高层组成 杰出科学家将担任该中心的主任和副主任 EC 将得到内部方法学核心和患者评估资源核心的支持。 咨询委员会、外部咨询委员会以及试点和可行性研究委员会。 审计委员会的具体目标是 (1) 为高效的工作提供行政和科学领导 在 PMSKD 中开展和传播创新团队科学，(2) 开发 推广计划以促进本地和全国 PMSKD 跨学科临床研究 (3) 通过创建和管理试点和可行性项目，提供测试新想法的机会 加强 PORTICO 目标的研究计划将由 AC 负责重点关注。 PORTICO 的服务、创新和教育产品将与那些 辛辛那提儿童医院和 辛辛那提大学医学院和国家资源和研究网络 AC 领导层关系密切 对于 AC，我们已经建立了强有力的领导层。 计划，以及活动的沟通、管理和评估计划以及 此外，AC 将管理外展计划，努力加强 PORTICO 的资源。 研究界支持已建立和早期职业生涯的新颖和创新工作 研究人员致力于推进 PMSKD 研究领域。