Animal Core

动物核心

• 批准号: 8112449
• 负责人: Gregory O Freden
• 金额: $ 86.78万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8112449
• 关键词: Animal Housing; Animal Husbandry; Animals; Autopsy; Caring; Containment; Control Animal; Ethics; Fostering; Human Resources; IACUC; Institutes; Legal; Mission; Monitor; Pathogenesis; Prevention strategy; Procedures; Research; Research Project Grants; Services; Workplace; animal facility; design; environmental enrichment for laboratory animals; meetings; pathogen; programs

Animal studies are critical to the scientific missions of the NEIDL institute. Virtually every research project that explores pathogenesis and treatment and prevention strategies as well as studies comparing infected to control animals and diverse/various/numerous pathogens and pathogenic strains will involve animal studies. The animal housing and operational facilities are well integrated to maximize space utilization while maintaining the ABSL-3 and ABSL-4 containment levels necessary for vital animal studies. The highcontainment animal zones provide space for animal housing, research procedures and postmortem examinations and support spaces for personnel and supplies. Some of the animal facility support functions are located outside the high-containment zones. This design strategy conserves valuable containment space and allows cage washing and other core animal facility support activities to be conducted at ABSL-1. Functions and Services Provided by the Core: Monitors and evaluates all activities involving animals on behalf of the Institutional Animal Care and Use, Committee (IACUC) to insure they meet the ethical and legal requirements for humane care and use, Provides an animal husbandry and technical support program, Develops and implements strategies for environmental enrichment of animals, Provides a program of veterinary care that utilizes current best practices, and Fosters a positive, supportive, and safe working environment for all personnel.

动物研究对于 NEIDL 研究所的科学使命至关重要。几乎每个研究项目 探索发病机制、治疗和预防策略以及比较感染者和感染者的研究 对照动物和多种/多种/众多病原体和致病菌株将涉及动物研究。 动物圈舍和操作设施完美结合，最大限度地提高空间利用率，同时 维持重要动物研究所需的 ABSL-3 和 ABSL-4 密封水平。高遏制 动物区为动物饲养、研究程序和尸检提供空间 人员和物资的检查和支持空间。一些动物设施支持功能 位于高密闭区域之外。这种设计策略保留了有价值的遏制 空间并允许在 ABSL-1 进行笼子清洗和其他核心动物设施支持活动。 核心提供的职能和服务：代表机构动物护理和使用委员会（IACUC）监测和评估涉及动物的所有活动，以确保它们符合人道护理和使用的道德和法律要求，提供畜牧业和技术服务支持计划， 制定和实施动物环境富集战略， 提供利用当前最佳实践的兽医护理计划，并 为所有人员营造积极、支持性和安全的工作环境。