The Psychobiology of Trauma and Resilience Across the Lifespan

一生中创伤和复原力的心理生物学

• 批准号: 8007121
• 负责人: DEAN Gaines KILPATRICK
• 金额: $ 5万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-05 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8007121
• 关键词: Address; Advocacy; Basic Science; Behavioral; Biological; Caring; Child Abuse and Neglect; Childhood; Clinical; Clinical Research; Clinical Sciences; Communities; Data; Development; Disasters; Disease; Event; Exposure to; Failure; Feedback; Funding; Genetic; Grant; International; Interpersonal Violence; Journals; Knowledge; Longevity; Los Angeles; Mental Depression; Minority Groups; Modeling; Molecular Genetics; National Institute of Mental Health; Neurosciences; Participant; Policies; Post-Traumatic Stress Disorders; Prevalence; Prevention; Public Health; Public Health Practice; Publishing; Research; Research Personnel; Risk; Site; Societies; Stress; Substance Use Disorder; Surveys; Terrorism; Translational Research; Translations; Trauma; Violence; War; Woman; base; clinical practice; design; experience; improved; innovation; meetings; programs; psychobiology; psychologic; psychosocial; public health relevance; resilience; social; symposium; web site

DESCRIPTION (provided by applicant): This application seeks funding for scientific presentations at the 26th, 28th, and 30th Annual Meetings of the International Society for Traumatic Stress Studies (ISTSS) to be held in Montreal (November 4-6, 2010), Los Angeles (November 1-3, 2012) and a site to be determined (November, 2014). We will replicate the successful model used in our current NIMH-funded conference grant. Each meeting has a core of scientific programming of basic and clinical science addressing important traumatic stress issues. The prevalence of exposure to potentially traumatic events (PTEs) such as child maltreatment, interpersonal violence, disasters, terrorism, and war is high, and exposure to PTEs increases risk of PTSD, depression, substance use disorders and perpetration of violence. Programming at the meetings will address barriers to better traumatic stress research and translation of clinical research to clinical practice that include: 1) fragmentation with respect to the types of PTEs studied; 2) lack of integration of traumatic stress research that incorporates genetic, molecular, behavioral, psychological, and public health levels of analysis and perspective; 3) failure to consider the developmental impact of PTEs experienced during childhood on risk for PTSD given exposure to PTEs occurring at later points during the lifespan; and 4) poor translation of basic science research to clinical research and of clinical research to clinical and public health practice. Specific aims are to: 1) organize annual meetings that engage research, clinical practice, and policy audiences in discussions about genetic, molecular, behavioral, psychological, and social influences on risk, resilience, prevention, and treatment of PTSD and related disorders in an effort to encourage development of better research and improved care; 2) integrate knowledge from these different perspectives and levels of analysis to improve scientific knowledge and scientifically informed clinical practice; and 3) disseminate information about key meeting themes and presentations to the scientific community via annual special sections in the Journal of Traumatic Stress. Under the direction of the P.I. and a Project Coordinating Committee, 20% of the content of the 2010, 2012, and 2014 Annual Meetings will be devoted to these issues. Keynote speakers, plenary speakers, and other presentations will be selected to insure that there is adequate programming of this type. Exemplary presentations will be summarized on the ISTSS website, and a special section based on these presentations will be published in JTS each year. The Coordinating Committee will insure that the program includes women and traditionally underrepresented racial/ethnic minorities. Survey feedback from meeting participants, data on media coverage, and citation data on articles published in Special Section of the JTS will be obtained. Note: Consistent with the new NIMH policy on conference grants, we will use the additional grant funding to achieve a fully sustainable annual meeting that incorporates program enhancements made possible by the grant so that no additional requests for NIMH conference grant funding will be necessary. PUBLIC HEALTH RELEVANCE: The proposed presentations within the 2010, 2012 and 2014 ISTSS annual Meetings are designed to address several barriers to improved traumatic stress research and clinical practice that include: 1) fragmentation with respect to type of potentially traumatic events (PTE) studied; 2) lack of integration of traumatic stress research that documents genetic, molecular, behavioral, psychological, or social findings or import to the field 3) failure to consider the developmental impact of PTEs experienced at different points in the lifespan; and 4) poor translation of research findings and their implications from traumatic stress researchers to clinical and public health practitioners. Specific aims are to: 1) organize annual meetings that engage research, practice, and policy audiences in a discussion about the genetic, molecular, behavioral, psychological, and social influences on resilience, prevention, and treatment of trauma-related problems in an effort to educate these disparate audiences and to encourage the development of innovative treatment and research; 2) integrate knowledge from genetic, biological, neuroscience, psychosocial, and public health perspectives to improve scientific knowledge and scientifically informed clinical practice and advocacy; and 3) disseminate information about key meeting themes and presentations to the scientific community via an annual special issues of the Journal of Traumatic Stress (JTS). This application seeks continued funding for a conference grant.

描述（由申请人提供）：本申请为在蒙特利尔举行的国际创伤压力研究学会（ISTSS）的第26、28和30届年度会议（2010年11月4-6日），洛杉矶（2012年11月1-3日）（2012年11月1-3日）和将于2014年11月（2014年11月1日）在蒙特利尔举行（2014年11月4-6日），为科学演讲提供资金。我们将复制当前NIMH资助的会议赠款中使用的成功模型。每次会议都是基础科学和临床科学的科学编程的核心，解决了重要的创伤性压力问题。暴露于潜在创伤事件（PTE）的患病率（例如儿童虐待，人际暴力，灾难，恐怖主义和战争）很高，PTES暴露会增加PTSD的风险，抑郁症，药物使用障碍和暴力犯罪。会议上的编程将解决更好的创伤性压力研究的障碍，并将临床研究转化为临床实践，其中包括：1）关于所研究的PTE类型的分裂； 2）缺乏结合遗传，分子，行为，心理和公共卫生分析和观点的创伤性压力研究的整合； 3）未能考虑童年时期经历的PTE对PTSD风险的发育影响，因为暴露于寿命后期发生的PTE； 4）对临床研究以及临床和公共卫生实践的基础科学研究以及临床研究的不良翻译不良。具体目的是：1）在讨论有关遗传，分子，行为，心理和社会对风险，韧性，预防和治疗PTSD及其相关疾病的遗传，分子，行为，心理和社会影响的讨论中，组织研究，临床实践和政策受众的年度会议，以鼓励开发更好的研究和改善护理； 2）从这些不同的角度和分析水平整合知识，以改善科学知识和科学知情的临床实践； 3）通过《创伤性压力杂志》中的年度特殊部门传播有关关键会议主题和演讲的关键主题和演示的信息。在P.I的指导下一个项目协调委员会，2012年和2014年年度会议内容的20％将致力于这些问题。主题演讲者，全体演讲者和其他演讲将被选为确保此类类型的足够编程。示例性演示将在ISTSS网站上汇总，并根据这些演示文稿的特殊部分每年在JTS中发布。协调委员会将确保该计划包括妇女和传统代表性不足的种族/族裔少数民族。会议参与者的调查反馈，有关媒体报道的数据以及有关JTS特别部分发表的文章的引文数据。注意：与新的NIMH有关会议赠款的政策一致，我们将使用额外的赠款资金来实现完全可持续的年度会议，该会议结合了赠款使计划的增强功能，因此无需对NIMH会议赠款资金提供其他要求。 公共卫生相关性：在2010年，2012年和2014年ISTS年度会议范围内的拟议演讲旨在解决改善创伤性压力研究和临床实践的几个障碍，其中包括：1）有关研究的潜在创伤事件类型（PTE）的分裂； 2）缺乏创伤性压力研究的整合，该研究记录了遗传，分子，行为，心理或社会发现或对领域的进口结果3）未能考虑生命周期中不同点所经历的PTE的发育影响； 4）研究发现的不良翻译及其从创伤性压力研究人员到临床和公共卫生从业人员的影响。具体目的是：1）在讨论有关遗传，分子，行为，心理和社会对韧性，预防和治疗与创伤相关问题的治疗的讨论中，组织会吸引研究，实践和政策受众的年度会议，以努力教育这些不同的受众并鼓励创新治疗和研究的发展； 2）从遗传，生物学，神经科学，社会心理和公共卫生的观点中整合知识，以改善科学知识和科学知情的临床实践和倡导； 3）通过《创伤性压力杂志》（JTS）的年度特殊问题传播有关关键会议主题和演讲的关键信息。该申请寻求继续为会议赠款提供资金。