Core A: Administrative Core

核心A：行政核心

• 批准号: 10708573
• 负责人: WILLIAM G HAWKINS
• 金额: $ 13.13万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-28 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10708573
• 关键词: Address; Advocacy; Animals; Bioinformatics; Biometry; Clinical Services; Clinical Trials; Collaborations; Communication; Community Health Education; Community Outreach; Contracts; Dedications; Development; Disparity; Documentation; Ensure; Faculty; Feedback; Funding; Grant; Group Meetings; Guidelines; Human; Institution; Leadership; Malignant neoplasm of pancreas; Manuscripts; Minority Participation; Minority Recruitment; Monitor; National Cancer Institute; Participant; Patient advocacy; Patients; Peer Review; Progress Reports; Protocols documentation; PubMed; Publications; Research; Research Personnel; Resource Sharing; Resources; Sampling; Travel; Underrepresented Minority; Universities; Update; Washington; anticancer research; career; meetings; member; peer; programs; web site; working group

PROJECT SUMMARY The Administrative Core aims to provide executive oversight and administrative support for all SPORE in Pancreatic Cancer projects and cores. The Administrative Core will monitor the activities of all program components, ensure compliance with local and federal grant administration guidelines, and facilitate communication and collaboration among program members. The specific aims of the Administrative Core are: Aim 1: Facilitate intra- and inter-SPORE communication, collaboration, and meetings. This core will be responsible for distributing SPORE-related materials, agendas, regulatory information, progress reports, and publications to SPORE faculty and staff. We will coordinate bi-monthly working group meetings, monthly SPORE Steering Committee meetings, and an annual retreat to facilitate exchange of ideas and use of shared resources. We will coordinate the External Advisory Board and Internal Advisory Board. We will maintain a dedicated website to provide progress updates and contact information, distribute quarterly updates to investigators highlighting resources available through the Biospecimen (Core B) and Biostatistics & Bioinformatics (Core C) Cores, and facilitate bidirectional flow of biospecimen samples and information. This core will also provide administrative oversight of multi-institution SPORE clinical trials. Aim 2: Provide administrative and fiscal oversight and support for all SPORE components. We will interact with Washington University's Grants and Contracts Office and National Cancer Institute staff to prepare and submit annual progress reports and complete other projects as needed. Aim 3: Coordinate the SPORE Developmental Research Program and Career Enhancement Program administrative activities. This core will solicit applications and coordinate review for the Career Enhancement Program (CEP) and Developmental Research Program (DRP). This core will monitor awardee progress, coordinate awardees’ travel to peer SPORE institutions, and facilitate use of core resources by awardees. Aim 4: Enhance participation of underrepresented minorities in all SPORE activities. The Core will oversee DRP and CEP initiatives to promote minority participation in SPORE clinical trials and pancreatic cancer research. We will accomplish this through leadership, community outreach and education, clinical services, clinical trial accrual auditing, support of disparities research, retention and recruitment of minorities, and communication with institutional disparities resources. Aim 5: Ensure advocacy issues are addressed in all aspects of research with patient participants. The Core will ensure that all SPORE components properly incorporate advocacy issues or concerns. We will accomplish this in two ways including patient advocacy and patient feedback. Aim 6: Assist investigators in preparing scholarly presentations, publications, regulatory documents, and all other SPORE-related products. This core will be responsible for completing documentation required for investigators presenting at local and national meetings and submitting of documents to institutional regulatory bodies (e.g., human and animal studies protocols), publications, and final peer-reviewed manuscripts supported by SPORE funds to PubMed Central immediately upon acceptance.

项目概要 行政核心旨在为所有 SPORE 提供执行监督和行政支持 胰腺癌项目和核心将监督所有计划的活动。 组成部分，确保遵守地方和联邦赠款管理准则，并促进 计划成员之间的沟通和协作。行政核心的具体目标是： 目标 1：促进 SPORE 内部和之间的沟通、协作和会议。 负责分发 SPORE 相关材料、议程、监管信息、进度报告和 我们将协调每两个月一次的工作组会议、每月一次的 SPORE 出版物。 指导委员会会议和年度务虚会，以促进思想交流和共享资源的使用。 我们将协调外部顾问委员会和内部顾问委员会。我们将维持一个专门的顾问委员会。 网站提供进展更新和联系信息，向调查人员分发季度更新 强调通过生物样本（核心 B）和生物统计与生物信息学（核心 C）可用的资源 核心，并促进生物样本样本和信息的双向流动。 对多机构 SPORE 临床试验的行政监督。 目标 2：为所有 SPORE 组成部分提供行政和财政监督和支持 我们将进行互动。 与华盛顿大学赠款和合同办公室以及国家癌症研究所工作人员一起准备和 提交年度进度报告并根据需要完成其他项目。 目标 3：协调 SPORE 发展研究计划和职业提升计划 该核心将征求申请并协调职业提升的审查。 计划（CEP）和发展研究计划（DRP）该核心将监控获奖者的进展， 协调获奖者前往同行 SPORE 机构的旅行，并促进获奖者使用核心资源。 目标 4：加强代表性不足的少数群体对所有 SPORE 活动的参与。 DRP 和 CEP 倡议促进少数群体参与 SPORE 临床试验和胰腺癌 我们将通过领导、社区外展和教育、临床服务来实现这一目标。 临床试验应计审计、差异研究支持、少数群体的保留和招募，以及 与机构差异资源的沟通。 目标 5：确保倡导问题在患者参与者研究的各个方面得到解决。 Core 将确保所有 SPORE 组件正确纳入倡导问题或担忧。 通过两种方式实现这一目标，包括患者倡导和患者反馈。 目标 6：协助研究人员准备学术报告、出版物、监管文件、 以及所有其他 SPORE 相关产品。该核心将负责完成所需的文档。 供调查人员在地方和国家会议上发言并向机构监管机构提交文件 支持的机构（例如人类和动物研究方案）、出版物和最终同行评审手稿 SPORE 资金在接受后立即转入 PubMed Central。