Integrative Environmental Health Sciences Facility Core

综合环境健康科学设施核心

• 批准号: 10165397
• 负责人: CATHERINE J KARR
• 金额: $ 16.9万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10165397
• 关键词: Address; Area; Basic Science; Biomedical Research; Child; Clinical; Clinical Research; Clinical Sciences; Collaborations; Collection; Communities; Consultations; Core Facility; Disasters; Discipline; Disease; Early Diagnosis; Environment; Environmental Health; Environmental Risk Factor; Epigenetic Process; Ethics; Evolution; Fostering; Fred Hutchinson Cancer Research Center; Funding; Funding Opportunities; Genetic; Genomics; Goals; Health; Health Policy; Health Sciences; Human; Individual; Interdisciplinary Study; Leadership; Methods; National Institute of Environmental Health Sciences; Occupational Health; Patients; Physiological; Population Study; Predisposition; Prevention; Public Health; Public Health Schools; Research; Research Design; Research Institute; Research Personnel; Resources; Sampling; Science; Scientist; Services; Structure; Technology; Testing; Time; Translational Research; Universities; Washington; base; catalyst; cohesion; community center; community engaged research; community engagement; data to knowledge; exposed human population; gene environment interaction; health practice; health science research; implementation science; improved; innovation; instrumentation; member; novel; organizational structure; population based; population health; programs; repository; research study; response; translational study; virtual

INTEGRATIVE ENVIRONMENTAL HEALTH SCIENCES FACILITY CORE ABSTRACT The Integrative Environmental Health Sciences Facility Core (IEHS-FC) acts as the navigator for EDGE Center interdisciplinary research. Here, investigators and trainees connect to Center services and a comprehensive consultation resource emphasizing clinical, translational, and population-based studies. The IEHS-FC facilitates Center member research along the translational continuum. Whether the investigator is involved in basic or experimental sciences, clinical studies or observational population-based studies, the IEHS-FC offers high quality advisement, methods, and resources to enhance EHS research, inform public health policy and practice, and impact individual and population health. The IEHS-FC fosters interdisciplinary team science research throughout the University of Washington by integrating basic sciences research with population-based and clinical EHS research to improve early detection and prevention of environmentally related disorders. The Core also helps to identify collaborative opportunities within the greater NIEHS Core Centers program by promoting and connecting researchers to respond to the EHS Core Centers collaborative research funding opportunities. The IEHS-FC is re-structured with two focus areas in addition to the navigator function. The clinical, translational, and population-based studies focus area remains. Investigators will continue to benefit from services covering study design and execution, clinical and physiological testing, collection and storage of human samples, access to controlled-human exposure facilities, and identifying patient groups and sample repositories. In this renewal, new resources are added to support translational research to address emerging needs in Disaster Research Response (DR2), an emerging focus of the Center. This second focus area supports investigators in the conduct of rigorous, timely, ethical, and safe environmental health disaster research response. The IEHS-FC is the gateway for EDGE Center investigators, fostering interdisciplinary and novel EHS research. Its emphasis on clinical and translational sciences, individual susceptibility factors, and gene-environment interactions are in keeping with the goals of NIEHS to maximize the utilization of human population-based studies in EHS research. By offering expert consultation, research services and appropriate referrals to EDGE Center investigators, the IEHS-FC enhances the interconnectedness of the EDGE Center Facility Cores, the Community Engagement Core (CEC), and other EDGE Center components. By leveraging the outstanding resources of the EDGE Center, the Department of Environmental & Occupational Health Sciences, the School of Public Health and the broader UW biomedical research community, the IEHS-FC provides an important and valued hub for NIEHS funded investigators at the UW, the Fred Hutchinson Cancer Research Center, Seattle Children’s Research Institute, the Center’s community partners, and the local, regional, and national EHS research community.

综合环境健康科学设施核心 抽象的 综合环境健康科学设施核心（IEHS-FC）充当Edge的导航器 中心跨学科研究。在这里，调查人员和受训人员将中心服务连接起来 全面的咨询资源强调临床，转化和基于人群的研究。 IEHS-FC的最爱中心成员研究沿翻译连续性。调查员是否是 参与基础科学或实验科学，临床研究或基于人群的研究， IEHS-FC提供高质量的建议，方法和资源来增强EHS研究，告知公众 卫生政策和实践，影响个人和人口健康。 IEHS-FC养育 整个华盛顿大学跨学科团队科学研究通过整合基本 科学研究与基于人群和临床EHS研究，以改善早期检测和预防 与环境相关的疾病。核心还有助于确定在 大型NIEHS核心中心计划通过促进和连接研究人员来响应EHS核心 中心协作研究资金机会。 除导航器功能外，IEHS-FC还具有两个焦点区域的重新结构。临床， 仍然存在转化和基于人群的研究重点领域。调查人员将继续从中受益 涵盖研究设计和执行，临床和物理测试，收集和存储的服务 人类样本，获得受控的人类暴露设施，并识别患者群体和样品 存储库。在此续约中，添加了新资源来支持翻译研究以解决新兴 灾难研究反应的需求（DR2），这是该中心的新兴重点。第二个焦点区域 支持调查人员进行严格，及时，道德和安全的环境健康灾难 研究反应。 IEHS-FC是边缘中心调查员的门户，促进了跨学科和 新颖的EHS研究。它强调临床和翻译科学，个人易感性因素以及 基因环境相互作用与NIEH的目标保持一致，以最大程度地利用人类 基于人群的EHS研究研究。通过提供专家咨询，研究服务和适当的 转介到边缘中心调查员，IEHS-FC增强了边缘的互连性 中心设施核心，社区参与核心（CEC）和其他边缘中心组件。 通过利用边缘中心的杰出资源，环境部和 职业健康科学，公共卫生学院和更广泛的大学生物医学研究 社区，IEHS-FC为UWS的NIEHS资助的调查员提供了一个重要而有价值的枢纽， 西雅图儿童研究所的弗雷德·哈钦森癌症研究中心，该中心的 社区合作伙伴以及地方，地区和国家EHS研究界。