Clinical and Translational Science Center (UL1)

临床和转化科学中心 (UL1)

• 批准号: 7912459
• 负责人: JULIANNE L IMPERATO-MCGINLEY
• 金额: $ 39.29万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-24 至 2011-09-23
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7912459
• 关键词: Clinical; Translational; Science; Center; UL1

The development of the Clinical and Translational Science Center (CTSC) fulfills the mission to advance the nation's clinical research enterprise of moving translational research seamlessly from bench to bedside and to the community. The Center represents our vision to deliver the vast knowledge of recent biomedical advances to clinical application for meaningful healthcare practices andto nurture multidisciplinary translational research education and training. The CTSC has been designed to capture the collective of intellectual capital, cutting-edge resources and diverse patient base of partnering institutions and to integrate them for maximum translational research benefits. As lead institution, Weill Cornell Medical Center (WCMC) will serve as an academic home through which essential resources, technological tools and education programs can be efficiently shared and managed. The partner institutions comprising the CTSC are also neighbors located on York Avenue. Within the immediate area are: WCMC, including Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences and the Weill Cornell Campus of NewYork-Presbyterian Hospital; Memorial Sloan-Kettering Cancer Center; and the Hospital for Special Surgery. In close proximity on the East Side of Manhattan are: Hunter College School of Nursing, Hunter College Center for the Study of Gene Structure and Function/Research Center for Minority Institutions and the Cornell University Cooperative Extension in New York City. The resulting cluster of institutions forms a unique and cohesive biomedical complex fulfilling the NIH roadmap initiative of breaking-down institutional and disciplinary silos to accelerate translational research. Separately, the partner institutions are superb centers of intellectual and academic excellence, thus their integration into the CTSC will harness their distinctive characteristics and hasten clinical and translational research breakthroughs for improved patient care. The trans-institutional governance structure outlined in this application and supplemented by a comprehensive systems-based evaluation process are important in overcoming bureaucracies and barriers. New initiatives were sculpted and programs with a history of collaboration between partners were broadened and restructured. The key elements of the CTSC are: 1) development of novel clinical and translational methodologies; 2) pilot and collaborative translational and clinical studies; 3) biomedical informatics; 4) design, biostatistics and clinical research ethics; 5) regulatory knowledge and support; 6) participant and clinical interaction resources; 7) community engagement and research; 8) translational technologies and resources; 9) research education, training and career development; and 10) other program functions. The CTSC is a vital link between the academic, research and clinical practice functions of partner institutions and will provide an important continuum in translational research.

临床和转化科学中心（CTSC）的发展履行了推进的使命 国家的临床研究企业是将翻译研究从长凳上无缝移动到床边，再到 社区。该中心代表了我们的愿景，即将最近的生物医学进步的广泛了解 有意义的医疗保健实践和培养多学科翻译研究的临床应用 教育和培训。 CTSC旨在捕获智力资本的集体 合作机构的资源和多样化的患者基础，并将其整合起来以最大程度地翻译 研究好处。 作为领导机构，威尔·康奈尔医学中心（WCMC）将作为一个学术住所 基本资源，技术工具和教育计划可以有效地共享和管理。这 由CTSC组成的合作伙伴机构也位于约克大道（York Avenue）。在附近的区域 为：WCMC，包括Weill Cornell医学院，Weill Cornell医学科学研究生院和 Weill Cornell校园的纽约 - 长主教医院；纪念斯隆 - 凯特林癌症中心；和 特殊手术医院。曼哈顿东侧附近的近距离 猎人学院基因结构和功能研究中心护理/少数民族研究中心 纽约市的机构和康奈尔大学合作扩展。由此产生的集群 机构构成了一个独特而有凝聚力的生物医学综合体，以实现闯入的NIH路线图计划 制度和纪律处分，以加速转化研究。另外，合作伙伴机构是 精湛的智力和学术卓越中心，因此它们融入CTSC将利用他们的 独特的特征以及促进改善患者护理的临床和转化研究突破。 本申请中概述的跨机构治理结构，并补充了全面的 基于系统的评估过程对于克服官僚主义和障碍很重要。 雕刻了新计划，并扩大了合作伙伴之间合作历史的计划 并重组。 CTSC的关键要素是：1）新型临床和翻译的发展 方法论； 2）试点和协作转化和临床研究； 3）生物医学信息学； 4）设计， 生物统计学和临床​​研究伦理； 5）监管知识和支持； 6）参与者和临床 交互资源； 7）社区参与和研究； 8）翻译技术和资源； 9） 研究教育，培训和职业发展； 10）其他程序功能。 CTSC是一个重要链接 在伙伴机构的学术，研究和临床实践功能之间，将提供重要的 转化研究的连续性。