CLINICAL AND TRANSLATIONAL SCIENCE CENTER

临床和转化科学中心

• 批准号: 8366104
• 负责人: JULIANNE L IMPERATO-MCGINLEY
• 金额: $ 49.12万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8366104
• 关键词: Center for Translational Science Activities; Clinical Sciences

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The development of the Clinical and Translational Science Center (CTSC) fulfills the mission to advance the nation's clinical research enterprise of moving translational research seamlessly from bench to bedside and to the community. The Center represents our vision to deliver the vast knowledge of recent biomedical advances to clinical application for meaningful healthcare practices and to nurture multidisciplinary translational research education and training. The CTSC has been designed to capture the collective of intellectual capital, cutting-edge resources and diverse patient base of partnering institutions and to integrate them for maximum translational research benefits. As lead institution, Weill Cornell Medical Center (WCMC) will serve as an academic home through which essential resources, technological tools and education programs can be efficiently shared and managed. The partner institutions comprising the CTSC are also neighbors located on York Avenue. Within the immediate area are: WCMC, including Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences and the Weill Cornell Campus of NewYork-Presbyterian Hospital; Memorial Sloan-Kettering Cancer Center; and the Hospital for Special Surgery. In close proximity on the East Side of Manhattan are: Hunter College School of Nursing, Hunter College Center for the Study of Gene Structure and Function/Research Center for Minority Institutions and the Cornell University Cooperative Extension in New York City. The resulting cluster of institutions forms a unique and cohesive biomedical complex fulfilling the NIH roadmap initiative of breaking-down institutional and disciplinary silos to accelerate translational research. Separately, the partner institutions are superb centers of intellectual and academic excellence, thus their integration into the CTSC will harness their distinctive characteristics and hasten clinical and translational research breakthroughs for improved patient care. The trans-institutional governance structure outlined in this application and supplemented by a comprehensive systems-based evaluation process are important in overcoming bureaucracies and barriers. New initiatives were sculpted and programs with a history of collaboration between partners were broadened and restructured. The key elements of the CTSC are: 1) development of novel clinical and translational methodologies; 2) pilot and collaborative translational and clinical studies; 3) biomedical informatics; 4) design, biostatistics and clinical research ethics; 5) regulatory knowledge and support; 6) participant and clinical interaction resources; 7) community engagement and research; 8) translational technologies and resources; 9) research education, training and career development; and 10) other program functions. The CTSC is a vital link between the academic, research and clinical practice functions of partner institutions and will provide an important continuum in translational research.

该子项目代表了 CTSA 资金百分比的估计 被用于广泛的研究领域（艾滋病研究、儿科研究或 临床试验）。 列出的总成本只是 CTSA 金额的估计值 该研究领域的基础设施，而不是直接资助 NCRR 向子项目或子项目工作人员提供的补助金。 临床和转化科学中心（CTSC）的发展履行了推动国家临床研究事业的使命，将转化研究从实验室无缝转移到临床和社区。该中心代表了我们的愿景，即将最新生物医学进展的丰富知识传递到临床应用，以实现有意义的医疗保健实践，并培育多学科转化研究教育和培训。 CTSC 旨在捕获合作机构的智力资本、尖端资源和多样化患者基础的集合，并将它们整合起来以获得最大的转化研究效益。作为牵头机构，威尔康奈尔医学中心 (WCMC) 将作为一个学术家园，通过它可以有效地共享和管理重要的资源、技术工具和教育项目。 CTSC 的合作伙伴机构也位于约克大道附近。附近地区有： WCMC，包括威尔康奈尔医学院、威尔康奈尔医学研究生院和纽约长老会医院威尔康奈尔校区；纪念斯隆-凯特琳癌症中心；和特殊外科医院。曼哈顿东区附近有：亨特学院护理学院、亨特学院基因结构和功能研究中心/少数族裔机构研究中心以及康奈尔大学纽约市合作推广中心。由此产生的机构集群形成了一个独特且有凝聚力的生物医学综合体，实现了 NIH 打破机构和学科孤岛以加速转化研究的路线图倡议。另外，合作机构都是卓越的知识和学术中心，因此它们并入 CTSC 将利用其独特的特点，加速临床和转化研究的突破，从而改善患者护理。本申请中概述的跨机构治理结构并辅以基于系统的综合评估流程，对于克服官僚主义和障碍非常重要。制定了新的举措，并扩大和重组了具有合作伙伴之间合作历史的项目。 CTSC 的关键要素是：1）开发新的临床和转化方法； 2) 试点和合作转化及临床研究； 3）生物医学信息学； 4）设计、生物统计学和临床​​研究伦理； 5）监管知识和支持； 6）参与者和临床互动资源； 7）社区参与和研究； 8）转化技术和资源； 9）研究教育、培训和职业发展； 10) 其他程序功能。 CTSC 是合作机构学术、研究和临床实践职能之间的重要纽带，并将为转化研究提供重要的连续体。