Integrative Training in the Neurobiology of Addictive Behaviors

成瘾行为神经生物学的综合训练

• 批准号: 10626027
• 负责人: Donald Hedeker
• 金额: $ 36.75万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10626027
• 关键词: Addictive Behavior; Neurobiology; Training

PROJECT SUMMARY/ABSTRACT The Integrative Training in the Neurobiology of Addictive Behaviors Program at The University of Chicago offers training for both pre- and postdoctoral trainees in drug abuse-related research. Our core faculty trainers are productive researchers with successful training credentials. Their expertise ranges from molecular biology, electrophysiology, pharmacology and animal models of drug addiction, to the social, behavioral and psychopharmacological aspects of human drug use, including etiology, treatment and drug policy. Quantitative approaches and reproducibility are emphasized. Our goal is to prepare the next generation of scientists to investigate the etiology, prevention and treatment of drug abuse with integrative approaches. We propose a program for 3 predoctoral and 4 postdoctoral trainees. Trainees will be supported by the Training Program for 1-3 years (usually 2 years). Trainees obtain specialized intensive training in their ‘home’ laboratories, but they are also exposed to the full breadth of addictions research outside their own area. To ensure that there is substantial interaction among the trainees, and between trainees and trainers, we schedule bi-weekly meetings consisting of journal club presentations and seminars by invited speakers. Didactic courses range from molecular cellular neuroscience to systems and behavioral neuroscience, from statistics to computational neuroscience and bioinformatics, from genetics and epidemiology to treatment and policy. One other mechanism by which our T32 has enhanced training experience is the “externship” program, in which our trainees receive mentored experiences in laboratories or settings removed from their own. The organizational structure includes an Executive Committee making overall training decisions, a Selection Committee to ensure a good flow and balance of trainees, a Program and Review Committee to monitor trainees’ progress, and an External Advisory Committee to provide expert outside consultation. The University of Chicago provides a unique environment with both a long history of interdisciplinary collaboration and recently a significant commitment to neuroscience research. This provides a rich intellectual context for trainees in drug abuse related research. In addition to the trainees supported by the T32, we have added Associate Members so that any trainee who is interested in addiction research can participate in any of the T32 sponsored activities. This allows us to bring together other trainees and faculty from across campus to raise consciousness about addiction research and its relevance to other disciplines. It brings in new expertise to the group and significantly enriches training opportunities. We will devote resources to recruiting underrepresented minorities and we will provide comprehensive training in ethical conduct of research.

项目摘要/摘要 芝加哥大学上瘾行为计划神经生物学的综合培训 在与药物滥用有关的研究中为学前和博士后学员提供培训。我们的核心教师教练 是拥有成功培训证书的生产研究人员。他们的专业知识范围从分子生物学， 对社会，行为和行为和动物成瘾的电生理学，药理学和动物模型 人类药物使用的心理药理方面，包括病因，治疗和药物政策。定量 强调方法和可重复性。我们的目标是为下一代科学家做好准备 通过综合方法研究药物滥用的病因，预防和治疗。 我们为3个占主导地位和4名博士后学员的计划提出了一个计划。学员将得到 培训计划已有1 - 3年（通常为2年）。学员在“家”中获得了专门的密集培训 实验室，但他们也暴露于自己地区以外的成瘾研究的全部广度。到 确保培训之间以及培训和培训师之间存在大量互动，我们 安排每两周举行的会议，包括日记俱乐部演讲和由受邀演讲者组成的时间。 教学课程从分子细胞神经科学到系统和行为神经科学范围 从遗传学和流行病学到治疗和 政策。我们的T32增强培训经验的另一个机制是“实习”计划， 我们的受训者获得了从自己的实验室或设置中获得的指导经验。这 组织结构包括一个执行委员会做出整体培训决策，选择 委员会确保受训者的良好流程和平衡，计划和审查委员会监视 受训者的进步和外部咨询委员会，以提供外部咨询专家。 芝加哥大学提供了一个独特的环境，既有跨学科的悠久历史 合作以及最近对神经科学研究的重要承诺。这提供了丰富的知识分子 吸毒相关研究学员的背景。除了T32支持的受训者外，我们还有 添加的同学成员，以使任何对成瘾研究感兴趣的学员都可以参与 T32赞助活动。这使我们能够将其他学员和教师从校园整个 提高对成瘾研究及其与其他学科的相关性的意识。它带来了新的专业知识 向小组致敬，并显着丰富培训机会。我们将投入资源招聘 代表性不足的少数民族，我们将提供有关研究道德行为的全面培训。