Administrative and Field Coordination Core

行政和现场协调核心

• 批准号: 10622447
• 负责人: Mohammed Kumail Ali
• 金额: $ 59.09万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-15 至 2027-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10622447
• 关键词: Ancillary Study; Asia; COVID-19 pandemic; Cardiovascular Diseases; Chronic Disease; Clinical; Collaborations; Communication; Communities; Core Grant; Data; Data Analyses; Data Collection; Electronics; Ensure; Environmental Risk Factor; Ethics; Federal Government; Feedback; Funding; Goals; Group Meetings; Growth; Health; Human Resources; Incentives; India; Infrastructure; Institution; Interdisciplinary Study; Knowledge; Laboratories; Lead; Leadership; Link; Local Government; Logistics; Manuals; Measurement; Measures; Methods; Monitor; Multiomic Data; National Heart, Lung, and Blood Institute; Newsletter; Occupational activity of managing finances; Outcome; Participant; Pathway interactions; Phenotype; Play; Policies; Principal Investigator; Process; Productivity; Program Research Project Grants; Progress Reports; Protocols documentation; Publications; Publishing; Quality Control; Reporting; Research Personnel; Risk Reduction; Role; Science; Scientist; Services; Site; Standardization; Strategic Planning; Structure; Training; United States National Institutes of Health; Universities; Update; Vision; Work; adjudication; aspirate; biobank; cardiometabolic risk; cohesion; cohort; data exchange; data handling; data management; design; disease phenotype; disorder control; experience; innovation; multiple omics; operation; organizational structure; outreach; precision medicine; quality assurance; recruit; repository; retention rate; success; synergism; web site

PROJECT SUMMARY / ABSTRACT (Administrative and Field Coordination Core) To maximize the cohesiveness and impacts of the Precision Cardiovascular Disease Phenotyping and Pathophysiological Pathways in the CARRS cohort (Precision-CARRS), the Administrative and Field Coordination (AFC) Core will provide scientific and operational governance (Aim 1); field and laboratory oversight (Aim 2); and communication services (Aim 3) to support this multi-site Program Project Grant (PPG). The AFC Core will build on ten years of productive collaboration and seamless coordination between Emory University and its partner institutions in India to conduct cross-national scientific discovery. The Core will be based at Emory and the Centre for Chronic Disease Control (CCDC). The AFC Core-Emory will leverage existing administrative infrastructure, the multiple Principal Investigators, Project Leads, and the Data Management and Analysis Core leadership team. The AFC Core-Emory will oversee governance and communication functions. The AFC Core- CCDC is comprised of the CVD Phenotyping Core, Delhi and Chennai Site Leads, and field and laboratory leaders. The AFC Core-CCDC will oversee field data collection and laboratory quality oversight processes, drawing on ten years of experience, local knowledge, partnerships with communities, and connections with local and national government. The AFC Core will establish a Steering Committee to facilitate cohesion and linkage across the three Cores and four Projects. To provide effective governance (Aim 1), the AFC Core will house an Executive Committee comprised of established scientists with a strong track-record of collaboration who co- developed the PPG’s vision and organizational structure. The Core has recruited an illustrious Internal Advisory Group, and laid out plans for an External Advisory Group to obtain strategic guidance and raise the visibility of Precision-CARRS. The AFC Core will augment previously-developed transparent administrative policies and processes, including regular reporting mechanisms to ensure PPG goals are being met. Policies and processes are intended to stimulate efficiency and cohesiveness across the PPG. To support quality assurance and control for all data collection, handling, and laboratory methods (Aim 2), the AFC Core houses the Field Operations and Laboratory Committee which is comprised of investigators with expertise and experience in managing the CARRS Cohort. This group will update and operationalize manuals of operation, training, monitoring, and reporting to include precision measures that will be collected in the coming five years of the PPG. To promote effective internal communication, dissemination, and grow collaborations and impact (Aim 3), the AFC Core will expand the existing Publication, Presentation, and Ancillary Studies Committee. The AFC Core will also establish new channels of interaction, tracking, and reporting. Through its mix of structures, activities and personnel, the AFC Core is poised to support this PPG’s cross-cutting goals, scientific impacts, and visibility.

项目摘要 /摘要（行政和现场协调核心） 为了最大程度地提高精度心血管疾病体系型和影响的凝聚力和影响 CARRS队列（精密卡尔斯）的病理生理途径，行政和领域 协调（AFC）核心将提供科学和运营治理（AIM 1）；现场和实验室监督 （目标2）;和通信服务（AIM 3）支持此多站点计划项目赠款（PPG）。亚足联 核心将建立在埃默里大学和埃默里大学之间的十年产品协作和无缝协调的基础上 其在印度的合作伙伴机构进行跨国科学发现。核心将基于Emory， 慢性疾病控制中心（CCDC）。 AFC核心遗嘱将利用现有的管理 基础设施，多个主要研究人员，项目领导以及数据管理和分析核心 领导团队。 AFC核心遗嘱将监督治理和沟通功能。 AFC核心 - CCDC完成了CVD表型核心，德里和钦奈站点的铅以及实验室和实验室 领导者。 AFC Core-CCDC将监督现场数据收集和实验室质量监督流程， 利用十年的经验，当地知识，与社区的伙伴关系以及与当地的联系 和国民政府。亚足联核心将建立一个指导委员会，以促进凝聚力和连接 在三个核心和四个项目中。为了提供有效的治理（AIM 1），AFC核心将容纳 执行委员会完成了成熟的科学家，并拥有强大的合作记录，并共同完成 发展了PPG的愿景和组织结构。核心招募了一个杰出的内部咨询 小组，并制定了外部咨询小组的计划，以获得战略指导并提高可见性 精密卡车。 AFC核心将增加以前开发的透明行政政策，并 过程，包括定期的报告机制，以确保实现PPG目标。政策和过程 旨在刺激整个PPG的效率和凝聚力。支持质量保证和控制 对于所有数据收集，处理和实验室方法（AIM 2），AFC核心包含现场操作，并且 实验室委员会正在完成具有专业知识和经验的调查员 Carrs队列。该小组将更新和操作操作，培训，监视和 报告包括将在PPG的未来五年内收集的精确度量。促进 有效的内部沟通，传播和发展协作和影响（AIM 3），AFC核心将 扩大现有的出版物，演示和辅助研究委员会。 AFC核心也将建立 新的互动，跟踪和报告的渠道。通过其结构，活动和人员的混合 AFC Core被中毒以支持该PPG的跨切割目标，科学影响和可见性。