Administrative and Field Coordination Core

行政和现场协调核心

• 批准号: 10333813
• 负责人: Mohammed Kumail Ali
• 金额: $ 59.74万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-15 至 2027-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10333813
• 关键词: Ancillary Study; Asia; COVID-19 pandemic; Cardiovascular Diseases; Chronic Disease; Clinical; Collaborations; Communication; Communities; Core Grant; Data; Data Analyses; Data Collection; Ensure; Environmental Risk Factor; Ethics; Federal Government; Feedback; Funding; Goals; Group Meetings; Growth; Health; Human Resources; Incentives; India; Infrastructure; Institution; Interdisciplinary Study; Knowledge; Laboratories; Lead; Leadership; Link; Local Government; Logistics; Manuals; Measurement; Measures; Methods; Monitor; Multiomic Data; National Heart, Lung, and Blood Institute; Newsletter; Occupational activity of managing finances; Outcome; Participant; Pathway interactions; Phenotype; Play; Policies; Principal Investigator; Process; Productivity; Program Research Project Grants; Progress Reports; Protocols documentation; Publications; Publishing; Quality Control; Reporting; Research Personnel; Risk Reduction; Role; Science; Scientist; Services; Site; Spouses; Standardization; Strategic Planning; Structure; Training; United States National Institutes of Health; Universities; Update; Vision; Work; adjudication; base; biobank; cardiometabolic risk; cohesion; cohort; data exchange; data format; data handling; data management; design; disease phenotype; disorder control; experience; innovation; multiple omics; operation; organizational structure; outreach; precision medicine; quality assurance; recruit; repository; retention rate; success; synergism; web site

PROJECT SUMMARY / ABSTRACT (Administrative and Field Coordination Core) To maximize the cohesiveness and impacts of the Precision Cardiovascular Disease Phenotyping and Pathophysiological Pathways in the CARRS cohort (Precision-CARRS), the Administrative and Field Coordination (AFC) Core will provide scientific and operational governance (Aim 1); field and laboratory oversight (Aim 2); and communication services (Aim 3) to support this multi-site Program Project Grant (PPG). The AFC Core will build on ten years of productive collaboration and seamless coordination between Emory University and its partner institutions in India to conduct cross-national scientific discovery. The Core will be based at Emory and the Centre for Chronic Disease Control (CCDC). The AFC Core-Emory will leverage existing administrative infrastructure, the multiple Principal Investigators, Project Leads, and the Data Management and Analysis Core leadership team. The AFC Core-Emory will oversee governance and communication functions. The AFC Core- CCDC is comprised of the CVD Phenotyping Core, Delhi and Chennai Site Leads, and field and laboratory leaders. The AFC Core-CCDC will oversee field data collection and laboratory quality oversight processes, drawing on ten years of experience, local knowledge, partnerships with communities, and connections with local and national government. The AFC Core will establish a Steering Committee to facilitate cohesion and linkage across the three Cores and four Projects. To provide effective governance (Aim 1), the AFC Core will house an Executive Committee comprised of established scientists with a strong track-record of collaboration who co- developed the PPG’s vision and organizational structure. The Core has recruited an illustrious Internal Advisory Group, and laid out plans for an External Advisory Group to obtain strategic guidance and raise the visibility of Precision-CARRS. The AFC Core will augment previously-developed transparent administrative policies and processes, including regular reporting mechanisms to ensure PPG goals are being met. Policies and processes are intended to stimulate efficiency and cohesiveness across the PPG. To support quality assurance and control for all data collection, handling, and laboratory methods (Aim 2), the AFC Core houses the Field Operations and Laboratory Committee which is comprised of investigators with expertise and experience in managing the CARRS Cohort. This group will update and operationalize manuals of operation, training, monitoring, and reporting to include precision measures that will be collected in the coming five years of the PPG. To promote effective internal communication, dissemination, and grow collaborations and impact (Aim 3), the AFC Core will expand the existing Publication, Presentation, and Ancillary Studies Committee. The AFC Core will also establish new channels of interaction, tracking, and reporting. Through its mix of structures, activities and personnel, the AFC Core is poised to support this PPG’s cross-cutting goals, scientific impacts, and visibility.

项目摘要/摘要（行政和现场协调核心） 最大限度地提高精准心血管疾病表型分析的凝聚力和影响力 CARRS 队列（Precision-CARRS）、行政和现场的病理生理学途径 协调 (AFC) 核心将提供科学和运营治理（目标 1）； （目标 2）；以及通信服务（目标 3），以支持 AFC 的多站点计划项目拨款 (PPG)。 Core 将建立在埃默里大学和埃默里大学之间十年的富有成效的合作和无缝协调的基础上。 其在印度开展跨国科学发现的合作机构将设在埃默里大学和 慢性病控制中心 (CCDC) 将利用现有的管理机构。 基础设施、多名首席研究员、项目负责人以及数据管理和分析核心 亚足联核心埃默里领导团队将监督管理和沟通职能。 CCDC 由 CVD 表型核心、德里和金奈基地负责人以及现场和实验室组成 AFC核心-CCDC将监督现场数据收集和实验室质量监督流程， 凭借十年的经验、当地知识、与社区的伙伴关系以及与当地的联系 亚足联核心将设立一个指导委员会，以促进凝聚力和联系。 为了提供有效的治理（目标 1），AFC 核心将设有一个 执行委员会由具有良好合作记录的知名科学家组成，他们共同 制定了 PPG 的愿景和组织结构。The Core 聘请了一位杰出的内部顾问。 集团，并制定了外部顾问小组的计划，以获得战略指导并提高 Precision-CARRS。AFC 核心将增强先前制定的透明管理政策和 流程，包括确保实现 PPG 目标的定期报告机制。 旨在提高整个 PPG 的效率和凝聚力，以支持质量保证和控制。 对于所有数据收集、处理和实验室方法（目标 2），AFC 核心设有现场操作和 实验室委员会由具有管理专业知识和经验的研究人员组成 CARRS 小组将更新和实施操作、培训、监测和管理手册。 报告包括将在 PPG 未来五年内收集的精确措施以促进。 有效的内部沟通、传播以及扩大合作和影响力（目标 3），亚足联核心将 扩大现有的出版、演示和辅助研究委员会 亚足联核心也将成立。 通过其结构、活动和人员的组合，互动、跟踪和报告的新渠道。 AFC Core 准备支持该 PPG 的跨领域目标、科学影响和知名度。