Center for Environmental and Health Effects of PFAS

PFAS 环境与健康影响中心

基本信息

批准号：
10747757
负责人：
CAROLYN J MATTINGLY
金额：
$ 73万
依托单位：
NORTH CAROLINA STATE UNIVERSITY RALEIGH
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-04-19 至 2024-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10747757
关键词：
Address Animals Area Back Blood Blood Tests Blood specimen Categories Chemicals Collection Communities Diagnostic Reagent Kits Engineering Ensure Fright Funding Future Health Health Professional Human Individual Internet Intervention Laboratories Location Measures Medical Medicine Methods Nafion National Health and Nutrition Examination Survey Newsletter North Carolina Parents Participant Persons Plants Poly-fluoroalkyl substances Public Health Randomized Recommendation Recording of previous events Reporting Research Project Grants Sampling Self Administration Serum Superfund Technology Test Result Testing Thyroid Gland Time Training United States National Academy of Sciences Work community engagement comparison group coronavirus disease drinking water exposed human population field study follow-up high risk improved manufacture member novel sample collection self testing social media study population substance use water treatment webinar

项目摘要

Abstract The NC State Center for Environmental and Health Effects of PFAS focuses on understanding the implications of PFAS exposure in humans and animals in the Cape Fear River Basin of North Carolina. The Cape Fear River in North Carolina is characterized by high levels of a variety of PFAS (per-and poly-fluoroalkyl substances) throughout the watershed. The specific chemicals vary by location with the lower Cape Fear characterized by the presence of novel fluoroethers from chemical manufacturing near Fayetteville, NC, while upstream, the levels of legacy PFAS such as PFOA and PFOS are elevated and frequently exceed the drinking water advisory levels for these chemicals. To better characterize the diversity of PFAS exposures among impacted communities along the Cape Fear River, we have developed this supplement proposal to: 1) further characterize human exposure in communities upriver from Fayetteville, 2) improve turnaround time for report back of PFAS blood results and evaluate a self-administered method for PFAS blood testing, and 3) expand community engagement regarding the recent National Academies of Sciences, Engineering, and Medicine recommendations for PFAS testing and medical management for communities throughout the Cape Fear River Basin.

抽象的北卡罗来纳州 PFAS 环境与健康影响中心致力于了解其影响北卡罗来纳州开普菲尔河流域人类和动物的 PFAS 暴露情况。开普菲尔河北卡罗来纳州的特点是多种 PFAS（全氟烷基物质和多氟烷基物质）含量较高整个分水岭。具体化学物质因地点而异，开普菲尔下游地区的特点是北卡罗来纳州费耶特维尔附近的化学制造过程中存在新型氟醚，而上游的水平传统 PFAS（例如 PFOA 和 PFOS）的含量升高，并经常超过饮用水建议水平对于这些化学品。为了更好地描述受影响社区中 PFAS 暴露的多样性在 Cape Fear River 中，我们制定了此补充提案，以： 1) 进一步描述人类接触的特征在费耶特维尔上游的社区，2) 缩短 PFAS 血液结果报告的周转时间，评估 PFAS 血液检测的自我管理方法，以及 3) 扩大社区参与美国国家科学院、工程院和医学院最近提出的 PFAS 测试建议整个开普菲尔河流域社区的医疗管理。