Alzheimer's Disease and Related Dementias Innovation Incubator (InnovaTor)

阿尔茨海默病及相关痴呆症创新孵化器 (InnovaTor)

• 批准号: 10738969
• 负责人: JEFFREY L. CUMMINGS
• 金额: $ 25.35万
• 依托单位: UNIVERSITY OF NEVADA LAS VEGAS
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10738969
• 关键词: Achievement; Address; Advocacy; Agreement; Alzheimer' s Disease; Alzheimer' s disease patient; Alzheimer' s disease related dementia; Asian Americans; Biotechnology; Black American; Businesses; Capital; Career Choice; Career Mobility; Caring; Clinical Trials; Communities; Complex; Development; Doctor of Philosophy; Economic Development; Ecosystem; Education; Educational Curriculum; Employment; Entrepreneurship; Exercise; Faculty; Family; Funding; Goals; Government; Grant; Hispanic Populations; Hispanic-serving Institution; Immersion; Incubators; Individual; Industry; Infrastructure; Institution; Instruction; Intellectual Property; Internships; Investments; Journalism; Knowledge; Laws; Leadership; Learning; Licensing; Marketing; Medical; Minority-Serving Institution; Native Americans; Neurologist; Nonprofit Organizations; Pacific Island Americans; Participant; Patients; Policies; Population Heterogeneity; Principal Investigator; Problem Solving; Process; Productivity; Public Health; Regulatory Affairs; Research; Research Personnel; Resources; Role; Schools; Science; Secure; Series; Small Business Innovation Research Grant; Small Business Technology Transfer Research; Structure; Students; United States National Institutes of Health; Writing; academic program; aging population; biopharmaceutical industry; brain health; career; commercialization; drug development; editorial; experience; improved; innovation; insight; interest; mild cognitive impairment; minority student; operation; outreach; pharmacovigilance; pre-clinical; programs; southern nevada; synergism; undergraduate student

PROJECT SUMMARY/ABSTRACT Alzheimer’s Disease and Related Dementias (ADRD) are growing challenges to the public health and have unmet needs that can be addressed through: Specific Aim 1) innovation and entrepreneurship; Specific Aim 2) non-academic research-based careers; and Specific Aim 3) academic ADRD drug development. These three themes will be developed in seminars, internships, lived experiences, discussions, and supervised projects of the UNLV Brain Health Innovation Incubator (InnovaTor). The InnovaTor will be Co-Led by Principal Investigator (PI) Jeffrey Cummings, MD, ScD, an experienced ADRD investigator and trialist and PI Jamie Schwartz, MBA, Director of Industry and Business Engagement for the UNLV Office of Economic Development to create a science-business leadership team. The InnovaTor will be a platform to help students identify research products that have commercial value, protect intellectual property, initiate a start-up company, secure funding, promote commercialization, and advance a marketing campaign (Specific Aim 1). The curriculum will include an introduction to SBIR and STTR grant development. In addition to on-going seminars, a 1-week summer Entrepreneurship Immersion Experience engaging UNLV students and others in discussions, projects, and team exercises will be hosted by the InnovaTor. An annual Innovation Day will involve campus-wide activities to attract participants to the InnovaTor and provide insights into the opportunities for ADRD-related entrepreneurship. Discussions of non-academic career alternatives will be led by individuals with roles in government science administration, advocacy, non-profit organizations, science writing and editing, policy think tanks, and investment (Specific Aim 2). The InnovaTor has established a strategic alliance with Eli Lilly and Company to have industry- based faculty interact with participants and educate about research-based careers in biopharma. Drug development discussions will emphasize the academic-industry interface with associated start-up and entrepreneurial opportunities (Specific Aim 3). An Innovator Club will be comprised of current and past InnovaTor participants to encourage entrepreneurship and to support an evolving start-up community. An agile InnovaTor structure will be supported by a Steering Committee, External Advisory Board, and an assessment team. Defined milestones will guide the development of the InnovaTor. Outreach to UNLV programs as well as other educational institutions in Southern Nevada will be led by an Innovation NavigaTor including a program to attract undergraduate students (Pre-CubaTor). UNLV is both a Hispanic-Serving Institution and an Asian American and Native American Pacific Islander-Serving Institution providing an opportunity to build programs to attract minority students to InnovaTor activities. The InnovaTor will interact with NIH and NSF-funded programs at UNLV, UNLV innovation resources (Lee Business School, Boyd School of Law, Office of Economic Development), and local community biotechnology firms and organizations. The Brain Health InnovaTor will build a culture of innovation and entrepreneurship devoted to ADRD.

项目摘要/摘要 阿尔茨海默氏病和相关痴呆症（ADRD）对公共卫生的挑战越来越大，并且 未满足的需求可以通过：特定目的1）创新和企业家精神；具体目标2） 非学术研究的职业；和特定目的3）学术ADRD药物开发。这三个 主题将以半手，实习，现场经验，讨论和监督项目开发 UNLV大脑健康创新孵化器（Innovator）。创新者将由首席研究员共同领导 （PI）医学博士Jeffrey Cummings，SCD，经验丰富的ADRD调查员和审判员以及Pi Jamie Schwartz，MBA， UNLV经济发展办公室的行业和商业参与总监创建一个 科学企业领导团队。创新者将是一个平台，可帮助学生识别研究产品 具有商业价值，保护知识产权，启动初创公司，安全资金，促进的商业价值 商业化并推进营销活动（特定目标1）。课程将包括 SBIR和STTR Grant Development简介。除了正在进行的半小伙子，一个1周的夏天 企业家的沉浸体验使UNLV学生和其他人参与讨论，项目和团队 练习将由创新者主持。年度创新日将涉及范围内的活动以吸引 参与创新者的参与者，并洞悉与ADRD相关的企业家精神的机会。 关于非学术职业替代方案的讨论将由政府科学中扮演角色的个人领导 管理，倡导，非营利组织，科学写作和编辑，政策智囊团以及投资 （特定目标2）。该创新者已经与Eli Lilly和Company建立了战略联盟，以拥有行业 - 基于的教职员工与参与者互动，并教育有关生物制药的基于研究的职业。药品 开发讨论将强调与相关的启动的学术行业界面和 创业机会（特定目标3）。创新俱乐部将完成当前和过去的创新者 参与者鼓励企业家精神并支持不断发展的创业社区。敏捷创新者 结构将得到指导委员会，外部顾问委员会和评估团队的支持。定义 里程碑将指导创新者的发展。向UNLV计划以及其他 内华达州南部的教育机构将由创新导航员领导 本科生（学前班）。 UNLV既是西班牙裔服务机构，又是亚裔美国人 美国原住民岛民服务机构提供了建立计划的机会 少数族裔学生进行创新活动。创新者将与NIH和NSF资助的计划进行互动 UNLV，UNLV创新资源（Lee商学院，博伊德法学院，经济办公室 开发）以及当地社区生物技术公司和组织。大脑健康创新者将 建立一种创新和企业家精神的文化。