Administrative Core

行政核心

• 批准号: 10242888
• 负责人: Lifang Hou
• 金额: $ 9.67万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10242888
• 关键词: AIDS related cancer; Acquired Immunodeficiency Syndrome; Adult; Advocate; Africa; American; Biological Markers; Cervical; Clinical; Collaborations; Communicable Diseases; Communication; Communities; Country; Coupled; Decision Making; Development Plans; Diagnostic; Educational Curriculum; Emergency Situation; Environment; Epigenetic Process; Foundations; Funding; Genomics; Goals; Government; Grant; HIV; Health; Health Policy; Health Promotion; Health education; Healthcare; Hepatitis B; Hepatitis C virus; Human Papillomavirus; Income; Infrastructure; Institutes; Institution; International; International AIDS; Lead; Leadership; Logistics; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Medical; Medical Education; Medical Research; Modernization; Molecular Epidemiology; Monitor; National Cancer Institute; Nigeria; Nigerian; Outcomes Research; Pathology; Pilot Projects; Policy Maker; Positioning Attribute; Prevention; Prevention Research; Primary carcinoma of the liver cells; Procedures; Process; Progress Reports; Public Health; Quality Control; Recording of previous events; Research; Research Personnel; Research Project Grants; Research Training; Resources; Scientist; Services; Specialist; Structure; TimeLine; Training Activity; Training Programs; Training Support; U-Series Cooperative Agreements; United States National Institutes of Health; Universities; Viral hepatitis; Virus Diseases; anticancer research; biomedical informatics; cancer care; career; community organizations; conflict resolution; disorder prevention; epidemiology study; epigenomics; global health; improved; infrastructure development; interdisciplinary approach; interest; international center; medical schools; meetings; operation; programs; response; statistics; virus related cancer

Project Summary We propose to establish a Consortium to study “Epigenomic Biomarkers of HIV-Associated Cancers in Nigeria.” Our research focus and core services development plan has been prioritized by our Nigerian partners at University of Jos (UniJos), Plateau State, Nigeria located in the center of the country and University of Lagos (UniLag), Lagos State in the densely populated southwest. Our focus on the epigenetics of HIV-associated hepatocellular carcinoma (HCC) and cervical cancer is justified by our extensive collaborative research history in viral diseases including HIV, human papilloma virus, hepatitis B and C viruses. Northwestern University and Mayo Medical School will serve as the high-income American partner institutions which is justified by the long history of research and research training collaboration with the Nigerian institutions coupled with its expertise in global health and ample complementary resources. The specific aims of the Administrative Core (AC) are: 1. establish the administration structure, communication mechanisms, decision making and conflict resolution processes for the U54 Consortium, 2. define the process for establishing and convening the External Advisory Group (EAG) which will include policy makers, health education specialists, institutional and government leaders, key opinion leaders and community advocates from Nigeria, and 3. coordinate administrative efforts between the Biomedical Informatics and Statistics Core (BISC), Career Enhancement Core (CEC), Pathology and Genomics Core (PGC) and Projects 1 (HCC) and 2 (cervical). The AC will be responsible for the overall administration, coordination and management of the Consortium as well as facilitation and coordination of meetings and activities of all cores and projects. The AC will be responsible for evaluating all Consortium activities, including monitoring project progress, monitoring proposed timelines, overseeing quality control procedures, and tracking and reporting progress towards stated research goals. We will develop short, medium and long term metrics for evaluating the quality, quantity, and continuity of the Consortium. An EAG will be formed and its membership will include: policy makers, health education specialists, institutional and government leaders, key opinion leaders and community advocates. The overall goal of the AC will be to support and facilitate research proposed in Projects 1 (HCC) and 2 (cervical), provide administrative logistics for training activities under the CEC, and manage research services provided by the BISC and PGC.

项目摘要 我们建议建立一个联盟，以研究“尼日利亚与HIV相关癌症的表观基因组生物标志物”。 我们的研究重点和核心服务开发计划已由我们的尼日利亚合作伙伴ATT优先考虑 尼日利亚高原州乔斯大学（UNIJOS），位于柜台和拉各斯大学 （Unilag），西南受欢迎的拉各斯州。 我们广泛的合作研究历史证明了肝细胞癌（HCC）和宫颈癌是合理的 在病毒疾病中，包括HIV，人乳头瘤病毒，乙型肝炎和C病毒。 Mayo医学院担任高收入美国合作伙伴研究所 研究与研究培训的历史与尼日利亚研究所耦合辅助Couths专业知识合作 全球健康和充足的互补资源。 建立管理结构，沟通机制，决策和冲突解决 U54财团的流程，2。定义建立和召开咨询的过程 小组（EAG）将包括政策制定者，健康教育专家，机构和政府领导人， 尼日利亚的关键选择领导者和社区倡导者，以及3。 生物医学信息学和统计核心（BISC），职业增强核心（CEC），病理学和 基因组核心（PGC）和项目1（HCC）和2（宫颈）将对整体响应 财团的管理，协调和管理以及促进和协调 所有核心和项目的会议和活动将重新统治所有财团 活动，包括监视项目进度，监视支撑时间表，监督质量控制 程序，跟踪和报告朝着既定的研究目标的进展。 以及评估财团的质量，数量和纪念品的长期指标。 成立及其成员将包括：政策制定者，健康教育专家，研究所和政府 领导者，主要意见领导者和社区倡导者的总体目标是支持和 促进项目1（HCC）和2（宫颈）提出的研究，为培训提供行政后勤 CEC下的活动以及管理BISC和PGC提供的研究服务。