Aviport: A Resource for Avian Biology

Aviport：鸟类生物学资源

基本信息

批准号：
10242751
负责人：
PARKER Bruce ANTIN
金额：
$ 63.37万
依托单位：
UNIVERSITY OF ARIZONA
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-12 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10242751
关键词：
Animal Model Biological Biology Biomedical Research Birds Cardiovascular system Chickens Collection Communities Computer Analysis Data Data Analyses Databases Development Developmental Biology Education and Outreach Ensure Experimental Models Funding Gene Expression Genes Genome Genomics Goals Hematopoiesis Housing Human Development Image Imaging technology Immunology In Situ Hybridization Integumentary system Limb Development Maintenance Malignant Neoplasms Metadata Modeling Modernization Nomenclature Organism Publications Publishing Quail Recording of previous events Renaissance Research Research Personnel Resources Standardization System Training Transgenic Animals Translating United States National Institutes of Health biomedical resource comparative comparative genomics data curation data management data to knowledge experience experimental analysis genome sequencing human disease human model improved large scale data model organisms databases neurogenesis new technology next generation programs somitogenesis tool virology web portal web services zebra finch

项目摘要

The overall goal of this resource program is to develop AviPort, a comprehensive genomic, biological and computational analysis portal for avian researchers and the broader biomedical research community. Since the beginning of the modern era of experimental biology in the late 1800’s, birds have been the premier non-mammalian model organism. Technological advances over the past decade have led to increased use of avian organisms, and a dramatic expansion of genomic and biological information for avian species. Lacking an avian model organism database (MOD), avian resources have been developed ad hoc and are dispersed across numerous platforms. A mechanism to unify these resources is critically needed, along with resources and platforms for large-scale data analysis. Accordingly, this proposal will establish AviPort, a comprehensive resource for the avian and broader biomedical research communities. By combining the information integration functions of a classic MOD with a state of the art platform for data management and experimental analysis, AviPort will represent a unique new resource for biomedical research. The goals of this proposal will be accomplished through the following overall specific aims: 1) Incorporate several existing high-value avian genomic and biological resources into a single integrated resource, and leverage larger external resources to provide robust data management and analysis capabilities. 2) Provide high quality, curated data to support biomedical discovery. This will be accomplished by improving the genomes of chicken and other key avian species, developing reference sets for key avian species, standardizing nomenclature, providing functional annotation, and providing data curation to enable integration of avian data types. 3) Disseminate data, results and training resources to ensure that biomedical researchers are able to effectively translate data into discoveries.

总体目的是发展Aviport耳机和生物医学界。大规模的数据分析将通过结合ARTIFF的整合功能来建立攻击性RCH社区，而Avipor t将代表Airique ainique New BioMedical研究。 -VIAN基因组和生物学作用到单个综合资源，以提供强大的数据管理能力。关键的鸟类物种，提供功能注释，并提供数据策划，以使鸟类数据类型的整合。