Washington University Institute of Clinical and Translational Sciences

华盛顿大学临床与转化科学研究所

• 批准号: 10598597
• 负责人: William G. Powderly
• 金额: $ 1017.84万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-19 至 2027-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10598597
• 关键词: Acceleration; Address; Adopted; Advocate; Affect; Biological; Biometry; Clinic; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Community Health; Complex; Conceptions; Data Set; Development; Disease; Dissemination and Implementation; Ecosystem; Education; Elderly; Ensure; Faculty; Genomics; Goals; Health; Healthcare; Healthcare Systems; Home; Human; Illinois; Individual; Industry; Inequity; Informatics; Infrastructure; Institution; Interdisciplinary Study; Intervention; Knowledge; Laboratories; Life; Longevity; Mentors; Methodology; Methods; Missouri; Multi-Institutional Clinical Trial; Outcome; Participant; Patient Care; Patients; Population; Population Heterogeneity; Process; Productivity; Qualifying; Research; Research Personnel; Resources; Rural Population; Science; Socioeconomic Factors; Special Population; Target Populations; Technology; Time; Training; Training Programs; Translating; Translational Research; Translations; Universities; Urban Population; Washington; Work; Workforce Development; archived data; base; clinical practice; community engagement; data integration; digital; dissemination science; diverse data; education research; fundamental research; health difference; health disparity; health inequalities; implementation design; implementation science; improved; informatics tool; innovation; inter-institutional; interoperability; multidisciplinary; multiscale data; programs; rural environment; skills; social determinants; translational impact; urban setting

Contact PD/PI: Powderly, William G. Overall Component, 7. Project Summary/Abstract: The Institute of Clinical and Translational Sciences aligns with the CTSA goals of developing innovative solutions to improve the efficiency, quality, and impact of translational science. We will pursue five aims: Aim 1: Advance interdisciplinary programs to develop, promote, mentor, and retain highly qualified and diverse faculty, trainees, and staff who translate scientific discoveries into action, thereby becoming agents for change in their institutions and communities. We will enhance our existing research education and training programs, expand and diversify our workforce, and promote team science approaches to conduct and translate high-impact research that has the potential for changing the health of our community. (Translational Workforce Development). Aim 2: Facilitate research designed for implementation by engaging diverse communities and stakeholders in multidisciplinary collaborative teams at all stages of the translational research process, thereby demonstrating the benefit and impact of translational science. We will improve community health by collaborating with patient advocates, developing new partnerships, advancing the science of collaboration, and capitalizing on strengths in implementation science (Collaboration and Engagement). Aim 3: Integrate research across individual lifespans and apply translational science in complex and diverse populations to improve individual and community health through meaningful research collaborations and sustainable partnerships. We will address health disparities across the lifespan and among special populations, identify challenges that differentially affect urban and rural populations, catalyze the formation of transdisciplinary teams, and evaluate the outcomes of our work (Integration). Aim 4: Drive innovation, quality, efficiency, and inclusion in translational research to enhance collaborations and catalyze the implementation of discovery science. We will solve key logistical roadblocks in translational science and implement innovative methods to engage stakeholders and research participants, thereby targeting different populations, life stages, and health states (Methods and Processes). Aim 5: Apply innovative informatics and biostatistics solutions to improve quality and efficiency at every stage of translational research, and create an ecosystem that integrates diverse data and facilitates the interoperability, use, and reuse of digital assets. We will ensure the interoperability of current and archived data sets, implement new informatics technologies to enhance investigator productivity, and promote the formation of interdisciplinary research teams (Informatics). Impact. Successful completion of these five aims will transform translational research, accelerate the dissemination of new innovations across our entire population, and strengthen and diversify our workforce. Project Summary/Abstract Page 235 Contact PD/PI: Powderly, William G. Overall Component 8.

联系PD/PI：粉状，William G. 总体组件，7。项目摘要/摘要： 临床和转化科学研究所与开发创新的CTSA目标保持一致 提高转化科学效率，质量和影响的解决方案。我们将追求五个目标： 目标1：提前跨学科计划，以开发，促进，指导和保留高素质 以及将科学发现转化为行动的多元化教师，学员和员工 成为其机构和社区变革的代理商。我们将增强现有研究 教育和培训计划，扩大和多样化我们的劳动力，并促进团队科学方法 进行和翻译高影响力的研究，有可能改变我们社区的健康状况。 （转化劳动力发展）。 目标2：通过参与多元化社区和 转化研究各个阶段的多学科合作团队的利益相关者 过程，从而证明了翻译科学的好处和影响。我们将有所改善 通过与患者倡导者合作，建立新的伙伴关系并推进科学来通过合作进行社区健康 协作，并利用实施科学的优势（协作和参与）。 目标3：整合跨个体寿命的研究，并将转化科学应用于复杂的和 通过有意义的研究来改善个人和社区健康的多样化人群 合作和可持续合作伙伴关系。我们将解决整个生命周期的健康差异 在特殊人群中，确定影响城市和农村人口差异的挑战，催化 跨学科团队的形成，并评估我们工作的结果（集成）。 目标4：推动创新，质量，效率和包容性转化研究以增强 合作和催化发现科学的实施。我们将解决关键后勤 转化科学中的障碍并实施创新方法，以吸引利益相关者和研究 参与者，从而针对不同的人群，生活阶段和健康状况（方法和过程）。 目标5：应用创新的信息学和生物统计学解决方案来提高质量和效率 翻译研究的每个阶段，创建一个整合多种数据和的生态系统 促进数字资产的互操作性，使用和再利用。我们将确保互操作性 当前和存档的数据集，实施新的信息学技术来提高研究者的生产率， 并促进跨学科研究团队的形成（信息学）。 影响。这五个目标的成功完成将改变转化研究，加速 在整个人群中传播新的创新，并增强和多样化我们的员工队伍。 项目摘要/摘要页面235 联系PD/PI：粉状，William G. 总体组件 8。