Washington University Institute of Clinical Translational Sciences

华盛顿大学临床转化科学研究所

• 批准号: 9889200
• 负责人: William G. Powderly
• 金额: $ 935.96万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-19 至 2022-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9889200
• 关键词: Active Learning; Address; Adopted; Advocate; Age; Archives; Biological Factors; Clinic; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Community Health; Complex; Data Set; Development; Disease; Ecosystem; Elderly; Ensure; Entrepreneurship; Environmental Risk Factor; Faculty; Fostering; Foundations; Genomics; Goals; Grant; Health; Healthcare; Healthcare Systems; Home environment; Hospitals; Human; Illinois; Individual; Industry; Informatics; Infrastructure; Institutes; Institution; Interdisciplinary Study; Knowledge; Life; Logistics; Longevity; Methodology; Methods; Missouri; Multi-Institutional Clinical Trial; Multicenter Trials; Outcome; Participant; Patient Care; Patients; Pediatric Hospitals; Persons; Pharmacy facility; Population; Population Heterogeneity; Process; Productivity; Research; Research Personnel; Resources; Rural Population; Saints; Science; Technology; Testing; Time; Training; Training Programs; Translating; Translational Research; Translations; Universities; Urban Population; Washington; Work; Workforce Development; base; clinical practice; college; design; digital; diverse data; education research; follower of religion Jewish; health difference; health disparity; improved; informatics tool; innovation; inter-institutional; interoperability; named group; novel; novel diagnostics; novel therapeutics; population health; programs; research data dissemination; translational scientist; Active Learning; Address; Adopted; Advocate; Age; Archives; Biological Factors; Clinic; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Community Health; Complex; Data Set; Development; Disease; Ecosystem; Elderly; Ensure; Entrepreneurship; Environmental Risk Factor; Faculty; Fostering; Foundations; Genomics; Goals; Grant; Health; Healthcare; Healthcare Systems; Home environment; Hospitals; Human; Illinois; Individual; Industry; Informatics; Infrastructure; Institutes; Institution; Interdisciplinary Study; Knowledge; Life; Logistics; Longevity; Methodology; Methods; Missouri; Multi-Institutional Clinical Trial; Multicenter Trials; Outcome; Participant; Patient Care; Patients; Pediatric Hospitals; Persons; Pharmacy facility; Population; Population Heterogeneity; Process; Productivity; Research; Research Personnel; Resources; Rural Population; Saints; Science; Technology; Testing; Time; Training; Training Programs; Translating; Translational Research; Translations; Universities; Urban Population; Washington; Work; Workforce Development; base; clinical practice; college; design; digital; diverse data; education research; follower of religion Jewish; health difference; health disparity; improved; informatics tool; innovation; inter-institutional; interoperability; named group; novel; novel diagnostics; novel therapeutics; population health; programs; research data dissemination; translational scientist

The Washington University (WU) Institute of Clinical and Translational Sciences (ICTS) has transformed clinical and translational science and research education in our region, and fostered productive scientific collaborations with our hub partner institutions University of Missouri-Columbia, Saint Louis University, St. Louis College of Pharmacy, BJC HealthCare, Barnes Jewish Hospital, and St. Louis Children's Hospital. The ICTS now proposes innovative aims that align well with the goals of the CTSA network, and will together catalyze discovery and advance research findings into real-world implementation to improve health and health care. 1. Provide interdisciplinary programs to develop, promote, and retain highly qualified and diverse faculty, trainees, and staff who can translate scientific discoveries into action. We will tailor our efforts to the needs of individuals, promote formation of transdisciplinary, inter-institutional, and inter-hub teams, rigorously assess our programs, and draw on our institutional and regional strengths in genomics, dissemination and implementation, and entrepreneurship. WORKFORCE DEVELOPMENT 2. Facilitate research that is designed for implementation by engaging diverse communities and stakeholders in collaborative teams at all stages of the translational research process. We will partner with patient advocates, propel the science of community and stakeholder engagement, break down barriers to allow integration of research findings into clinical practice, and capitalize on our local entrepreneurial ecosystem to apply discoveries to improve community health. COLLABORATION AND ENGAGEMENT 3. Integrate research across the lifespan and promote translational science within complex populations. The ICTS will address health disparities and differences in disease manifestations across different ages and among special populations, address both urban and rural populations, catalyze formation of transdisciplinary teams, and evaluate the clinical, community, and entrepreneurial outcomes of our researchers' work. INTEGRATION 4. Drive innovation, quality, and efficiency in the translational research, by using best practices and streamlined institutional processes to support high quality multi-center clinical trials and developing new methodological approaches to facilitate translational research. METHODS AND PROCESSES 5. Apply innovative informatics solutions to improve quality and efficiency at every stage of translational research, and create an ecosystem that integrates diverse data and facilitates the interoperability, use, and reuse of digital assets. INFORMATICS Successful completion of these aims will transform regional research, dissemination, and workforce development and will apply the considerable resources of WU and its partners to national CTSA goals to advance clinical and translational science and improve human health.

华盛顿大学（WU）临床与转化科学学院（ICT）已转变 我们地区的临床和转化科学与研究教育，并培养生产科学 与我们的HUB合作伙伴机构密苏里大学哥伦比亚大学圣路易斯大学的合作 路易斯药学院，BJC医疗保健，巴恩斯犹太医院和圣路易斯儿童医院。这 ICT现在提出的创新目标与CTSA网络的目标保持一致，并将共同融合 催化发现并将研究结果促进现实世界实施，以改善健康和健康 关心。 1。提供跨学科的计划，以发展，促进和保留高素质和多样化 可以将科学发现转化为行动的教师，学员和员工。我们将定制我们的努力 个人的需求，促进跨学科，机构间和中心间团队的形成， 严格评估我们的计划，并利用我们在基因组学方面的机构和区域优势， 传播和实施以及企业家精神。劳动力发展 2。促进为实施而设计的研究，通过吸引各种社区和 在转化研究过程的各个阶段，利益相关者在协作团队中。我们将合作 在患者倡导者的情况下，推动社区和利益相关者参与的科学，将障碍分解为 允许将研究结果整合到临床实践中，并利用我们的本地企业家 生态系统应用发现以改善社区健康。协作与参与 3。整合整个寿命的研究并在复杂的范围内促进转化科学 人群。信息通信技术将解决跨疾病表现的健康差异和差异 不同的年龄和特殊人口中，涉及城市和农村人口，催化形成 跨学科团队，评估我们的临床，社区和企业家成果 研究人员的工作。一体化 4。通过使用最佳实践和转化研究中的创新，质量和效率 简化了支持高质量多中心临床试验并开发新的机构过程 促进转化研究的方法学方法。方法和过程 5.应用创新的信息学解决方案，以提高每个阶段的质量和效率 翻译研究，并创建一个整合多种数据并促进的生态系统 数字资产的互操作性，使用和再利用。信息学 这些目标的成功完成将改变区域研究，传播和劳动力 开发并将将吴及其合作伙伴的大量资源应用于国家CTSA目标 提高临床和转化科学并改善人类健康。