Preventing alcohol misuse and consequences in vulnerable women

防止弱势女性滥用酒精及其后果

基本信息

批准号：
10264005
负责人：
Alyssa Norris
金额：
$ 19.18万
依托单位：
MIRIAM HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-15 至 2022-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10264005
关键词：
Accounting Address Adult Alcohol abuse Alcohol consumption Applications Grants Area Attention Award Behavior Behavioral Medicine Bisexual Clinical Trials Communities Control Groups Coping Skills Data Analyses Dependence Development Discrimination Distress Enrollment Evaluation Evidence based practice Faculty Feedback Funding Future Health Health education Heavy Drinking Heterosexuals Hospitals Human Injury Intervention Intervention Trial Interview Latino Lesbian Letters Manuals Measures Mentored Patient-Oriented Research Career Development Award Mentorship Methodology Methods Minority Minority Groups National Institute on Alcohol Abuse and Alcoholism Nature Needs Assessment Persons Prevention Prevention approach Prevention program Preventive Medicine Process Psychiatry Psychologist Public Health Randomized Randomized Controlled Trials Reporting Research Research Activity Research Personnel Research Support Risk Risk Factors Role Scientist Sex Orientation Sexuality Social Environment Stress Surveys Testing Theoretical model Training Training Activity United States National Institutes of Health Universities Victimization Vulnerable Populations Woman Women&apos s Group Work acceptability and feasibility adverse childhood events alcohol abuse therapy alcohol consequences alcohol intervention alcohol misuse alcohol misuse prevention alcohol research alcohol testing alcohol use disorder base binge drinking brief alcohol intervention brief intervention brief motivational intervention care preference clinical trial analysis cognitive interview comparison intervention coping dating violence design drinking evidence base experience follow-up group intervention health disparity high risk innovation interest intervention mapping men normative feedback patient engagement peer personalized normative feedback pilot trial post intervention primary outcome professor recruit reduced alcohol use secondary outcome sexual minority sexual violence skills sound substance use treatment systematic review theories therapy design therapy development young adult young woman

项目摘要

PROJECT ABSTRACT This Mentored Patient-Oriented Research Career Development Award (K23) will provide Dr. Alyssa Norris with the training and research activities needed to become an independent investigator focusing on the development and evaluation of innovative prevention approaches targeting young women’s alcohol use, with a specialized focus in sexual minority populations. Sexual minority women display markedly increased risk for hazardous alcohol use and alcohol consequences. Despite mounting evidence of these alcohol use disparities, there are no tested prevention approaches for sexual minority women. This is unwarranted given that sexual minority women evince unique risk factors for alcohol use and report dissatisfaction with current treatments, as well as that culturally-tailored programming for other minority groups is efficacious. The mentorship and training team includes expert psychologists in the following areas of research: brief interventions for alcohol misuse among young women and vulnerable populations (M. Carey; K. Carey); qualitative methodology to guide intervention development (Guthrie); longitudinal data analyses for clinical trials and latent analysis to guide intervention content (Dunsiger); and alcohol misuse among sexual minority women (Lewis). Further, I will continue to work as an Assistant Professor of Psychiatry and Human Behavior (DPHB) at Brown University and Research Scientist at the Centers for Behavioral and Preventive Medicine (CBPM) of The Miriam Hospital. DPHB and CBPM are dedicated to supporting K awardees from the completion of their training award activities to the transition into independent NIH funding. The DPHB currently has over 200 ongoing studies and $50 million in externally sponsored research and is dedicated to supporting early faculty in their transition to independence. Dr. Norris will apply the skills acquired through the proposed training activities to the development of theoretically-sound and evidence-based prevention programming to reduce alcohol misuse among sexual minority women. Specifically, Dr. Norris will develop a prevention program to reduce heavy alcohol use through three aims: (1) Formative needs assessment: (1a) systematic review of theoretical models of sexual minority women’s alcohol use, and (1b) in-depth interviews (N = 20) to guide intervention development through participatory engagement; (2) Refinement of treatment materials and delivery: (2a) secondary data analyses to determine meaningful normative feedback for sexual minority women (Kaysen), and (2b) cognitive interviews (N = 10) to guide the development of the intervention through participatory engagement; (3) Pilot randomized controlled trial (N = 70) comparing the intervention to an attention-matched control group to determine the feasibility and acceptability of the intervention, with a secondary focus on preliminary efficacy to guide future grant proposals.

项目摘要这项受到指导的以患者为导向的研究职业发展奖（K23）将为Alyssa Norris博士提供培训和研究活动需要成为专注于针对年轻女性专辑的创新预防方法的开发和评估使用，专门针对性少数人口。性少数族裔女性明显表现增加危险饮酒和酒精后果的风险增加。尽管有越来越多的证据酒精使用差异，没有针对性少数妇女的预防方法。这是鉴于性少数妇女证明了酒精使用和报告的独特风险因素对当前治疗的不满以及对其他少数群体的文化规划编程是有效的。心态和培训团队在以下领域中包括专家心理学家研究：年轻妇女和弱势群体中滥用酒精的简短干预措施（M. Carey; K. 凯里）；指导干预开发的定性方法（Guthrie）；纵向数据分析临床试验和潜在分析以指导干预含量（Dunsiger）；和性滥用性少数民族妇女（刘易斯）。此外，我将继续担任精神病学助理教授布朗大学的行为（DPHB）和行为和预防中心的研究科学家 Miriam医院的医学（CBPM）。 DPHB和CBPM致力于支持来自完成他们向独立NIH资金过渡的培训奖项活动。目前的DPHB 有200多项正在进行的研究和5000万美元的外部赞助研究，并致力于支持早期教师向独立过渡。诺里斯博士将运用通过提议获得的技能。培训活动以开发理论和基于证据的预防计划减少性少数妇女的滥用酒精。特别是，诺里斯博士将开发预防通过三个目的减少大量饮酒的计划：（1）形成性需求评估：（1a）系统性审查性少数妇女饮酒的理论模型，以及（1B）深入的访谈（n = 20）通过参与指导干预开发；（2）治疗材料的完善和交付：（2a）辅助数据分析以确定性少数妇女的有意义的正常反馈（凯森）和（2b）认知访谈（n = 10），以指导干预的发展参与参与；（3）将干预措施与一个随机对照试验（n = 70）与注意匹配的对照组，以确定干预的可行性和可接受性次要关注初步效率以指导未来的赠款建议。