Administrative Core
行政核心
基本信息
- 批准号:10254245
- 负责人:
- 金额:$ 13.43万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-09-25 至 2022-09-22
- 项目状态:已结题
- 来源:
- 关键词:Advisory CommitteesAdvocacyAdvocateAfrican AmericanAmericasAppointmentAreaAvena sativaBusinessesClinicalClinical ResearchCollaborationsCollectionCommunicationCommunitiesConflict of InterestDataDiagnosisEffectivenessEnsureEthnic groupEvaluationFacultyFamilyFosteringFoundationsFundingGoalsGrantHealthHealth ProfessionalHuman ResourcesIncidenceIndividualInfrastructureInvestigationIslandKnowledgeLeadLeadershipLupusMeasuresMedicalMentorsMissionMonitorMorbidity - disease rateNational Institute of Arthritis and Musculoskeletal and Skin DiseasesOutcomeOutputPatientsPerformancePilot ProjectsPreventionPrevention strategyProblem SolvingProductivityRaceReportingResearchResearch ActivityResearch InstituteResearch PersonnelResource SharingResourcesRheumatismRiskSamplingScientistSclerodermaSeaServicesSeveritiesSilverSouth CarolinaSystemic Lupus ErythematosusSystemic SclerodermaTimeTranslational ResearchTravelUnderrepresented MinorityUnited StatesUniversitiesUpdateclinical careclinical centerdesignexperiencefollow-uphealth disparityimprovedinnovationmeetingsmemberminority healthminority investigatoroperationoutreachprogramsresearch studyshared databasetoolweb site
项目摘要
PROJECT SUMMARY
The Administrative Core of the Core Center for Clinical Research (CCCR) for Improving Minority Health in
Rheumatic Diseases (IMHRD, pronounced IaMHeaRD) at the Medical University of South Carolina will provide
leadership and management for the center and implement a pilot projects program that will be funded entirely
with institutional commitments. The mission of this CCCR is to advance knowledge with respect to the clinical
care and health outcomes of African Americans who have, or who are at risk of developing, systemic lupus
erythematosus, scleroderma and other debilitating rheumatic diseases. The overarching goals of the
Administrative Core are to: (a) ensure the quality, validity, accessibility and applicability of the tools, services,
samples, data and other output of the CCCR cores, (b) foster interactions among basic, translational and clinical
scientists at MUSC and beyond to focus effectively on advancing prevention, diagnosis and treatment of
rheumatic diseases, and (c) facilitate appropriate dissemination of research results and resources. To achieve
these goals, we will pursue the following specific aims: 1. Provide leadership for the CCCR; 2. Coordinate and
manage CCCR organizational, operational and financial functions and evaluative activities; 3. Leverage
institutional infrastructure resources; 4. Develop and manage a multi-year Evaluation Plan; 5. Strengthen and
expand robust, effective communication, dissemination and outreach activities, fostering mutually productive
interactions among members of health professional, scientific and citizen communities; and 6. Provide a
competitive Pilot Projects Program. This core will be directed by Gary Gilkeson, MD, with assistance from two
Associate Directors, Jim Oates, MD, and Richard Silver, MD, an Executive Committee that includes core leaders
and Research Community representatives, an Internal Advisory Committee that includes institutional
stakeholders and patient advocates, and an External Advisory Committee that includes experts in the field with
experience leading other NIAMS centers. The Administrative Core staff will provide administrative support for
the center, administering and monitoring the finances, coordinating meetings and action items, and interfacing
with NIAMS staff and institutional personnel. The Administrative Core also will support educational and
dissemination activities to enhance the visibility and impact of the center within MUSC and the local community
and provide a forum for communicating and exchanging research ideas. The Administrative Core will nurture a
vibrant, interactive program of clinical and translational research that will advance our knowledge and resources
for improving the prevention, diagnosis, treatment and health outcomes for rheumatic diseases, notably systemic
lupus erythematosus (SLE) and systemic sclerosis (SSc), which occur significantly more often and with greater
severity in African Americans than in other racial and ethnic groups in the United States.
项目摘要
临床研究核心中心(CCCR)的行政核心,用于改善少数民族健康
南卡罗来纳州医科大学的风湿病(IMHRD,发音为Iamheard)将提供
该中心的领导和管理并实施一项试点项目计划,该计划将完全资助
具有机构承诺。该CCCR的任务是提高有关临床知识
非洲裔美国人的护理和健康成果
红斑,硬皮病和其他虚弱的风湿性疾病。总体目标
行政核心是:(a)确保工具,服务,有效性,可访问性和适用性,
CCCR核心的样本,数据和其他输出,(b)基本,翻译和临床之间的促进相互作用
MUSC及以后的科学家有效地专注于预防,诊断和治疗
风湿性疾病,(c)促进适当传播研究结果和资源。实现
这些目标,我们将追求以下具体目标:1。为CCCR提供领导; 2。坐标和
管理CCCR组织,运营和财务功能以及评估活动; 3。杠杆
机构基础设施资源; 4。制定和管理多年评估计划; 5。加强和
扩大强大的,有效的沟通,传播和外展活动,促进相互生产力
卫生专业,科学和公民社区成员之间的互动;和6。提供
竞争性试点项目计划。该核心将由马里兰州加里·吉尔克森(Gary Gilkeson)指导,并在两个
副董事,医学博士吉姆·奥茨(Jim Oates)和医学博士Richard Silver,包括核心领导者
研究社区代表,包括机构的内部咨询委员会
利益相关者和患者倡导者以及一个外部咨询委员会,其中包括该领域的专家
经验带领其他Niams中心。行政核心人员将为
中心管理和监视财务,协调会议和行动项目,并接触
与Niams的员工和机构人员。行政核心还将支持教育和
传播活动以增强中心在MUSC和当地社区的可见性和影响
并提供一个论坛来交流和交换研究思想。行政核心将培养
充满活力的临床和转化研究互动计划,这些计划将提高我们的知识和资源
用于改善风湿性疾病的预防,诊断,治疗和健康结果,特别是系统性
红斑狼疮(SLE)和全身性硬化症(SSC),其发生频率更高,更大的发生
非裔美国人的严重程度比美国其他种族和族裔群体的严重程度。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Gary S Gilkeson其他文献
Podocytes: A Potential Source of Nitric Oxide Production in Murine Lupus Nephritis
- DOI:
10.1016/j.freeradbiomed.2010.10.406 - 发表时间:
2010-01-01 - 期刊:
- 影响因子:
- 作者:
Ahmad K Mashmoushi;Ann F Hofbauer;Gary S Gilkeson;Jim C Oates - 通讯作者:
Jim C Oates
Role of Nitric Oxide in Podocyte Physiology in Lupus Nephritis
- DOI:
10.1016/j.freeradbiomed.2012.10.228 - 发表时间:
2012-11-01 - 期刊:
- 影响因子:
- 作者:
Ahmad K Mashmoushi;Ann F Hofbauer;Gary S Gilkeson;Jim C Oates - 通讯作者:
Jim C Oates
PSS61 - Nitric Oxide Modulation of Redox-Modulated Cytokines in Lupus Nephritis
- DOI:
10.1016/j.freeradbiomed.2013.10.476 - 发表时间:
2013-11-01 - 期刊:
- 影响因子:
- 作者:
Jim C Oates;Ahmad K Mashmoushi;Ann F Hofbauer;Gary S Gilkeson - 通讯作者:
Gary S Gilkeson
Gary S Gilkeson的其他文献
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{{ truncateString('Gary S Gilkeson', 18)}}的其他基金
A Phase II Controlled Trial of Allogeneic Mesenchymal Stem Cells for the Treatment of Refractory Lupus
同种异体间充质干细胞治疗难治性狼疮的 II 期对照试验
- 批准号:
10827646 - 财政年份:2018
- 资助金额:
$ 13.43万 - 项目类别:
A Phase II Controlled Trial of Allogeneic Mesenchymal Stem Cells for the Treatment of Refractory Lupus
同种异体间充质干细胞治疗难治性狼疮的 II 期对照试验
- 批准号:
10356843 - 财政年份:2018
- 资助金额:
$ 13.43万 - 项目类别:
Role of Gut Microbial Translocation in Initiating Autoimmunity
肠道微生物易位在启动自身免疫中的作用
- 批准号:
10291780 - 财政年份:2014
- 资助金额:
$ 13.43万 - 项目类别:
Role of Gut Microbial Translocation in Initiating Autoimmunity
肠道微生物易位在启动自身免疫中的作用
- 批准号:
9564333 - 财政年份:2014
- 资助金额:
$ 13.43万 - 项目类别:
Mesenchymal Stem Cell Therapy for Active Systemic Lupus Erythematosus
间充质干细胞治疗活动性系统性红斑狼疮
- 批准号:
8791443 - 财政年份:2014
- 资助金额:
$ 13.43万 - 项目类别:
Sex Differences in Gut Permeability; Impact on Autoimmunity
肠道渗透性的性别差异;
- 批准号:
8958705 - 财政年份:2014
- 资助金额:
$ 13.43万 - 项目类别:
Sex Differences in Gut Permeability; Impact on Autoimmunity
肠道渗透性的性别差异;
- 批准号:
8820340 - 财政年份:2014
- 资助金额:
$ 13.43万 - 项目类别:
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