Improving Minority Health in Rheumatic Diseases

改善少数民族风湿病健康

基本信息

批准号：
9902868
负责人：
Gary S Gilkeson
金额：
$ 55.05万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-25 至 2022-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9902868
关键词：
Address Adherence Administrative Supplement Advocate Affect African American Alabama Appointment Autoimmune Diseases Awareness Benchmarking Caucasians Chronic Disease Clinical Research Collaborations Color Communities Diagnostic Disease Economics Education Education and Outreach Emergency department visit Ethnic Origin Faculty Female Fostering Funding Future Genetic Genetic Diseases Grant Grant Review HIV Health Services Accessibility Hearing Historically Black Colleges and Universities Hospitalization Infrastructure Institution International Intervention Kidney Diseases Lupus Medical Medical center Mentors Mentorship Methodology Methods Morbidity - disease rate Mutation National Institute of Arthritis and Musculoskeletal and Skin Diseases Outcome Pathogenesis Patients Pharmaceutical Preparations Physicians Pilot Projects Population Prevalence Program Development Regimen Research Research Infrastructure Research Methodology Research Personnel Research Project Grants Research Support Resources Rheumatism Risk Factors Sampling Scleroderma Series Services Site South Carolina Systemic Lupus Erythematosus Techniques Technology Teleconferences Translating Travel Universities Woman Work Writing base career career development child bearing disparities in morbidity early screening ethnic disparity health disparity high risk high risk population improved inter-institutional medication compliance medication nonadherence member minority health mortality novel novel strategies programs ranpirnase response success young woman

项目摘要

ABSTRACT Systemic Lupus Erythematosus is a significant chronic disease with morbidity and mortality in primarily young women of color. Our current P30 CCCR grant “Improving Minority Health in Rheumatic Diseases” is composed of three cores, administrative, methodology and patient resource. These cores provide the infrastructure for studies directed at understanding the pathogenesis of lupus and scleroderma as a method to achieve better diagnostics and treatments for these diseases. In this Administrative Supplement to the P30 we are proposing two specific projects focused on decreasing ethnic disparities in lupus to be performed at MUSC and the University of Alabama at Birmingham. The first project is to provide awareness, education and early screening in young African American females through programs and efforts at Historically Black Colleges and Universities in South Carolina and Alabama. The second project is to utilize a patient advocate for high risk African American female lupus patients based on missed appointments, medication non adherence and ER visits at both institutions. The advocate will work with the patients to improve these parameters believing that such navigation in lupus will be as successful as similar efforts in HIV. We also propose an enhancement effort consisting of a pilot project each year for both institutions, a mentoring program for junior investigators in health disparities and cross institutional sharing of expertise. The CCCR program does not include projects, but only cores. We propose to utilize this supplement mechanism to pursue projects we believe will have direct impact on ethnic disparities in lupus.

抽象的全身性红斑狼疮是一种重要的慢性疾病，具有发病率和死亡率最初的有色女性。我们目前的P30 CCCR赠款“改善了少数民族健康风湿性疾病”由三个核心，行政，方法论和患者资源组成。这些核心提供了用于了解狼疮发病机理的研究的基础设施硬皮病是一种更好的诊断和治疗这些疾病的方法。在对P30的行政补充，我们提出了两个针对的特定项目在MUSC和阿拉巴马大学在狼疮中减少种族差异伯明翰。第一个项目是在Young中提供认识，教育和早期筛查非洲裔美国女性通过历史上的黑人大学的计划和努力，南卡罗来纳州和阿拉巴马州的大学。第二个项目是利用患者倡导者高风险的非裔美国雌性狼疮患者根据错过的约会，药物否两个机构的依从性和急诊就诊。倡导者将与患者合作以改进这些参数认为，狼疮中的这种导航将与类似的努力一样成功艾滋病病毒。我们还提出了每年都由试点项目组成的增强努力机构，针对健康分配和跨机构的初级调查人员的心理计划分享专业知识。 CCCR计划不包括项目，而仅包括核心。我们建议利用这种补充机制购买我们认为将直接影响种族的项目狼疮的差异。