Mentoring and Research in Patient-Oriented Integrative Medicine

以患者为中心的整合医学的指导和研究

基本信息

批准号：
10090566
负责人：
CHENCHEN WANG
金额：
$ 18.32万
依托单位：
TUFTS MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-12-01 至 2024-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10090566
关键词：
Acupuncture Therapy Affect Applications Grants Archives Authorship Award Bibliography Brain Childhood Chinese Traditional Medicine Chronic Chronic Fatigue Syndrome Clinical Clinical Research Clinical Sciences Clinical Trials Complementary Medicine Discipline Disease Progression Doctor&apos s Degree Dose Educational process of instructing Emotional Environment Environmental Risk Factor Epigenetic Process Ethics Family Fostering Foundations Funding Future Future Generations Goals Grant Health Health Promotion Healthcare Healthcare Systems Human Human Biology Individual Infrastructure Institutes Integrative Medicine Integrative Therapy Investigation Journals Massage Medical Medicine Mental Depression Mental Health Mental disorders Mentors Methodology Methods MicroRNAs Mid-Career Clinical Scientist Award (K24)Military Personnel Mind-Body Intervention Mission Modality Modeling Modern Medicine Morbidity - disease rate Neurobiology Neurosciences Neurosciences Research Outcome Pain Pathway interactions Patients Peer Review Persian Gulf Syndrome Persistent pain Personal Satisfaction Physicians Physiological Physiology Pilot Projects Politics Predisposition Progress Reports Psychology Publications Publishing Quality of life Records Regimen Research Research Personnel Research Project Grants Resources Rest Role Science Scientist Self Management Severities Stress Structure Symptoms Tai Ji Techniques Testing Therapeutic Time Traditional Medicine Training Translational Research United States Department of Veterans Affairs United States National Institutes of Health Universities Veterans Work body-mind career central sensitization chronic musculoskeletal pain chronic pain chronic pain management chronic pain patient clinical practice cognitive control combat comparative effectiveness study cost cost effective disability effective therapy evidence base experience experimental study fibromyalgia patients healing health care service utilization improved innovation interdisciplinary approach lifestyle intervention medical schools military veteran multidisciplinary neurobiological mechanism next generation novel nutrition opioid use osteoarthritis pain patient oriented patient oriented research professor programs public health relevance response social social factors sperm cell symptom management symptomatic improvement theories tool

项目摘要

MENTORING AND RESEARCH IN PATIENT-ORIENTED INTEGRATIVE MEDICINE The renewal Midcareer K24 Award is for Dr. Chenchen Wang to continue her mentoring of the next generation of physician-scientists and to contribute to patient-oriented Integrative Medicine research. Dr. Wang is Professor at Tufts University School of Medicine and Director of the Center for Complementary and Integrative Medicine and holds a strong record of research, publication, and mentoring. Her long-term goal is to advance the science of Integrative Medicine to promote health and healing. Her immediate goals are to obtain protected time to expand and strengthen her innovative, multi-method, and multidisciplinary translational research and mentoring programs for chronic disabling conditions. In the First Four Years of the K24, the PI has completed four major NIH-funded clinical trials studying comparative effectiveness of mind-body interventions for chronic musculoskeletal pain, developing integrative treatment approaches in military and veterans populations, and provided groundbreaking evidence on neurobiological and physiological responses to mind-body interventions. In this period, the PI published 61 articles, 8 as first author and 53 as senior author. The PI and her mentored team also received a new R01-like grant from the U.S. Department of Veterans Affairs to investigate the efficacy of a mind-body intervention for veterans suffering with Gulf War Illness. During the initial K24 period, she has been primary or co-primary mentor for 23 trainees with doctoral degrees. Her trainees authored 41 first-authored peer-reviewed publications and had 64 co-authorships. Ten of her trainees have their own NIH or other career grants. Dr. Wang’s multidisciplinary mentoring program, as well as her expertise on mind-body interventions, has been fully integrated into the research and teaching infrastructure of the Tufts Clinical and Translational Science Institute. With access to these outstanding resources and a long-recognized diverse training environment, her selected mentees will continue to obtain training in the rigorous scientific methodology, integrity, ethics, and grant applications necessary to stimulate high-quality, translational, patient-oriented research. The goal of this proposed K24 renewal is to build upon previous and current findings of the PI’s NIH-funded studies to: 1) expand and evaluate translational Integrative Medicine research for chronic disabling conditions in order to inform and benefit medical practice; 2) advance fundamental neuroscience and human biology research to understand the mechanisms of mind-body approaches, with the goal to improve chronic pain management; 3) identify critical unmet needs of novel effective therapies for managing symptoms; and 4) further strengthen the comprehensive interdisciplinary mentoring plan and extend opportunities to new scientists to guide future generations of Integrative Medicine researchers. This K24 renewal will therefore promote multidisciplinary patient-oriented research for the next generation of investigators in order to substantially advance the science on complementary and integrative medicine and contribute to the health, healthcare, and well-being for all.

面向患者的综合医学的指导和研究续签中级护理K24奖是为Chenchen Wang博士继续对下一代的心理身体科学家，并为以患者为导向的综合医学研究做出贡献。王博士是塔夫茨大学医学院教授，互补与综合中心主任医学并保持着庞大的研究，出版和心理记录。她的长期目标是进步综合医学科学促进健康和康复。她的直接目标是获得受保护的是时候扩展和加强她的创新，多方法和多学科的翻译研究和指导慢性残疾条件的计划。在K24的前四年，PI完成了四项研究研究的主要NIH资助临床试验心身干预措施对慢性肌肉骨骼疼痛的比较有效性，发展军事和退伍军人人口的治疗方法，并为神经生物学和身体对思维干预措施的反应。在此期间，PI出版了61 文章，第8位作为第一作者，53篇作为高级作家。 PI和她的指导团队还获得了新的R01式美国退伍军人事务部的授予，调查思维干预的效率遭受海湾战争疾病的退伍军人。在最初的K24期间，她是主要或共同主要的具有博士学位的23名学员的导师。她的实习生撰写了41个由同行评审的人。出版物，并拥有64次共同作者。她的十名学员有自己的NIH或其他职业赠款。博士王的多学科心理计划以及她在思维身体干预方面的专业知识一直是完全整合到簇临床和转化科学的研究和教学基础设施研究所。通过获得这些出色的资源和长期认可的潜水员培训环境，她选定的受训者将继续接受严格的科学方法，诚信，道德和刺激高质量，翻译，以患者为导向的研究所需的赠款申请。该提议的K24更新的目的是建立在PI资助的以前和当前的发现研究至：1）扩展和评估慢性残疾条件的翻译综合医学研究为了告知和受益医学实践； 2）提前的基本神经科学和人类生物学研究以了解思维方式方法的机制，以改善慢性疼痛的目标管理; 3）确定用于管理符号的新型有效疗法的关键未满足需求；和 4）进一步加强了全面的跨学科心理计划，并向新的机会扩大机会指导子孙后代研究人员的科学家。因此，此K24更新将促进下一代研究人员的多学科研究的多学科研究，以便实质上将科学推向了完整和综合的医学，并为健康做出了贡献，医疗保健和所有人的幸福。