Mentoring and Research in Patient-Oriented Integrative Medicine

以患者为中心的整合医学的指导和研究

基本信息

批准号：
10327635
负责人：
CHENCHEN WANG
金额：
$ 18.31万
依托单位：
TUFTS MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-12-01 至 2024-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10327635
关键词：
Acupuncture Therapy Affect Applications Grants Archives Authorship Award Bibliography Brain Childhood Chinese Traditional Medicine Chronic Chronic Fatigue Syndrome Clinical Clinical Research Clinical Sciences Clinical Trials Complementary Medicine Discipline Disease Progression Doctor&apos s Degree Dose Educational process of instructing Emotional Environment Environmental Risk Factor Epigenetic Process Ethics Family Fostering Foundations Funding Future Future Generations Goals Grant Health Health Promotion Healthcare Healthcare Systems Human Human Biology Individual Infrastructure Institutes Integrative Medicine Integrative Therapy Investigation Journals Massage Medical Medicine Mental Depression Mental Health Mental disorders Mentors Methodology Methods MicroRNAs Mid-Career Clinical Scientist Award (K24)Military Personnel Mind-Body Intervention Mission Modality Modeling Modern Medicine Morbidity - disease rate National Center for Complementary and Integrative Health Neurobiology Neurosciences Neurosciences Research Outcome Pain Pathway interactions Patients Peer Review Persian Gulf Syndrome Persistent pain Personal Satisfaction Persons Physicians Physiological Physiology Pilot Projects Politics Predisposition Progress Reports Psychology Publications Publishing Quality of life Records Regimen Research Research Personnel Research Project Grants Resources Rest Role Science Scientist Self Management Severities Stress Structure Symptoms Tai Ji Techniques Testing Therapeutic Time Traditional Medicine Training Translational Research United States Department of Veterans Affairs United States National Institutes of Health Universities Veterans Work body-mind career central sensitization chronic musculoskeletal pain chronic pain chronic pain management chronic pain patient clinical practice cognitive control combat comparative effectiveness study cost cost effective disability effective therapy evidence base experience experimental study fibromyalgia patients healing health care service utilization improved innovation interdisciplinary approach lifestyle intervention medical schools military veteran multidisciplinary neurobiological mechanism next generation novel nutrition opioid use osteoarthritis pain patient oriented patient oriented research professor programs public health relevance response social social factors sperm cell symptom management symptomatic improvement theories tool

项目摘要

MENTORING AND RESEARCH IN PATIENT-ORIENTED INTEGRATIVE MEDICINE The renewal Midcareer K24 Award is for Dr. Chenchen Wang to continue her mentoring of the next generation of physician-scientists and to contribute to patient-oriented Integrative Medicine research. Dr. Wang is Professor at Tufts University School of Medicine and Director of the Center for Complementary and Integrative Medicine and holds a strong record of research, publication, and mentoring. Her long-term goal is to advance the science of Integrative Medicine to promote health and healing. Her immediate goals are to obtain protected time to expand and strengthen her innovative, multi-method, and multidisciplinary translational research and mentoring programs for chronic disabling conditions. In the First Four Years of the K24, the PI has completed four major NIH-funded clinical trials studying comparative effectiveness of mind-body interventions for chronic musculoskeletal pain, developing integrative treatment approaches in military and veterans populations, and provided groundbreaking evidence on neurobiological and physiological responses to mind-body interventions. In this period, the PI published 61 articles, 8 as first author and 53 as senior author. The PI and her mentored team also received a new R01-like grant from the U.S. Department of Veterans Affairs to investigate the efficacy of a mind-body intervention for veterans suffering with Gulf War Illness. During the initial K24 period, she has been primary or co-primary mentor for 23 trainees with doctoral degrees. Her trainees authored 41 first-authored peer-reviewed publications and had 64 co-authorships. Ten of her trainees have their own NIH or other career grants. Dr. Wang’s multidisciplinary mentoring program, as well as her expertise on mind-body interventions, has been fully integrated into the research and teaching infrastructure of the Tufts Clinical and Translational Science Institute. With access to these outstanding resources and a long-recognized diverse training environment, her selected mentees will continue to obtain training in the rigorous scientific methodology, integrity, ethics, and grant applications necessary to stimulate high-quality, translational, patient-oriented research. The goal of this proposed K24 renewal is to build upon previous and current findings of the PI’s NIH-funded studies to: 1) expand and evaluate translational Integrative Medicine research for chronic disabling conditions in order to inform and benefit medical practice; 2) advance fundamental neuroscience and human biology research to understand the mechanisms of mind-body approaches, with the goal to improve chronic pain management; 3) identify critical unmet needs of novel effective therapies for managing symptoms; and 4) further strengthen the comprehensive interdisciplinary mentoring plan and extend opportunities to new scientists to guide future generations of Integrative Medicine researchers. This K24 renewal will therefore promote multidisciplinary patient-oriented research for the next generation of investigators in order to substantially advance the science on complementary and integrative medicine and contribute to the health, healthcare, and well-being for all.

面向患者的综合医学的指导和研究续签中级护理K24奖是为Wanghen Wang博士继续指导下一代的医师科学家，并为面向帕特门特的综合医学研究做出贡献。塔夫茨大学医学院教授，编译与融合中心主任医学并拥有大量的研究，出版和指导。综合医学科学促进健康和健康。是时候扩展和加强她的创新，多方法和多学科的翻译研究和指导慢性残疾条件的计划。在K24的头四年中，PI具有四个主要的NIH资助净资助的研究心体干预剂对慢性肌肉疼痛的比较有效性，形成整合军事和退伍军人人口的治疗方法，并为神经生物学和生理反应对思维体的间隔。文章，第8位作为第一作者和53位高级作家。美国退伍军人部的授予，调查心身干预的功效遭受海湾战争疾病的退伍军人。拥有23个博士学位的培训者的导师。出版物和64个共同作者。 Wang的多学科指导计划以及她的专业知识Ontervy Intervyntions一直是完全集成到TUTS临床和转化科学的研究和教学基础设施中研究所。选定的受训者将继续在严格的科学方法，完整性和道德规范中进行培训刺激高质量，转化，面向患者的研究所必需的赠款申请。支架K24更新的目的是建立在PI NIH资助的先前和当前发现的基础上研究至：1）扩展和评估慢性残疾条件的转化综合医学研究为了告知和受益医学实践； 2）研究以了解思维方式方法的机制，以改善慢性疼痛的目标管理; 3）确定有效治疗症状的新型有效疗法的重要需求； 4）进一步加强了全面的跨学科计划，并将开放率扩展到新的新新新的新新型科学家指导子孙后代的研究人员。促进下一代研究人员的多学科研究的多学科研究，以便大大推进了编译和综合医学的科学以及对健康的贡献，医疗保健和所有人的幸福。