Alterations and Renovations

改建和翻新

• 批准号: 10090987
• 负责人: Peter Stephen Steyger
• 金额: $ 12.78万
• 依托单位: CREIGHTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-05 至 2026-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10090987
• 关键词: Acids; Air; Auditory; Auditory Brainstem Responses; Award; Centers of Research Excellence; Chemicals; Complex; Computers; Core Facility; Drug Delivery Systems; Duct (organ) structure; Environment; Equipment; Floor; Health Services Research; Hearing; Hearing Tests; Hospitals; Image; Institution; Laboratories; Light; Lighting; Medical center; Microscope; Modernization; Nebraska; Pharmaceutical Chemistry; Research; Research Personnel; Research Project Grants; Savings; Services; Side; Solid; System; Technology; Testing; Therapeutic; Translational Research; Universities; Visual; boys; chemical synthesis; drug discovery; exhaust; foot; hearing impairment; operation; otoacoustic emission

ALTERATION & RENOVATION Project Summary/Abstract The Translational Hearing Center (THC) has established two functional cores: The Drug Discovery & Delivery Core (DDDC) and Auditory & Vestibular Technology Core (AVTC) to promote and enhance translational research on therapeutics for hearing loss. Currently all core facilities and equipment are located in close proximity to or within the Creighton University Core Facilities in the Criss I/II/III building complex, with additional satellite AVTCs located in neighboring institutions: University of Nebraska Medical Center (UNMC) and Boys Town National Research Hospital (BTNRH). To further empower our services for the Research Project Leaders (RPLs) and Center Investigators, we plan to align our facilities with our strength by creating new laboratory spaces through renovation of existing laboratories within first year of the COBRE award. To facilitate efficient chemical synthesis and analysis and facilitate new advanced imaging, we seek to renovate medicinal chemistry laboratory Criss II 326 and a new space for auditory hearing test laboratory Criss I 304. With these renovation projects completed, THC will have new, centralized laboratories for each core. These can be easily further expanded and integrated into the Creighton University Core Facilities. These will significantly enhance our services outlined in our proposal.

改变与翻新 项目摘要/摘要 翻译听证中心（THC）已经建立了两个功能核心：该药物 发现与交付核心（DDDC）以及听觉与前庭技术核心（AVTC） 促进和增强有关听力损失治疗剂的转化研究。目前都是核心 设施和设备靠近克雷顿大学核心附近或内部 Criss I/II/III建筑综合大楼中的设施，还有其他卫星AVTC位于 邻近机构：内布拉斯加州大学医学中心（UNMC）和男孩小镇 国家研究医院（BTNRH）。为了进一步赋予我们为研究项目的服务 领导者（RPL）和中心调查员，我们计划通过 通过在第一年内翻新现有实验室来创建新的实验室空间 鞋垫奖。促进有效的化学合成和分析并促进新的 高级成像，我们试图翻新药物化学实验室criss II 326和一个新的 听觉听力测试实验室Criss I 304的空间。这些翻新项目完成了， THC将为每个核心提供新的集中实验室。这些可以很容易地进一步 扩展并集成到Creighton University的核心设施中。这些将大大 加强我们的建议中概述的服务。