Biomedical Informatics

生物医学信息学

基本信息

批准号：
7714118
负责人：
THEODORE G KRONTIRIS
金额：
$ 10.71万
依托单位：
BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-09-01 至 2012-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7714118
关键词：
Adverse event Architecture Area Basic Science Bioinformatics Biotechnology Budgets Cancer Center Cancer Center Support Grant Cities Classification Clinical Clinical Research Clinical Trials Collaborations Collection Computer Hardware Computer software Computers Databases Depth Development Equipment Evaluation Fees Funding Funding Opportunities Human Resources Imagery Individual Informatics Information Management International Internet Intranet Joints Modeling Peer Review Performance Policies Process Publications Range Reporting Research Research Personnel Resource Sharing Resources Retrieval Secure Shared Resource Cancer Center Specialist Standards of Weights and Measures Supercomputing System Systems Analysis Systems Biology Technology Training Programs Translational Research Vendor Work base biomedical informatics cancer Biomedical Informatics Grid cost effectiveness data integration data management improved informatics training member open source platform-independent programs size

项目摘要

The Biomedical Informatics Core was established in 1998 to meet the information management needs of Cancer Center investigators. The Core provides a broad range of hardware, software and personnel resources that serve many investigators and several other shared resource facilities. The Core also works in collaboration with City of Hope and Cancer Center governance committees to promulgate standards, optimize systems and minimize redundancy through continued integration of data, databases, applications and processes. Over the last five years, BIC has become the most widely used Cancer Center shared resource, and Core usage continues to increase each year. A new subscription-based chargeback policy was implemented in October 2003, and chargeback revenue has increased from $7,250 in 2003 to $66,700 in 2006. Since the last competitive renewal, over 1/4 (276/1001) of all Cancer Center peer-reviewed publications involved the use of informatics shared resources. Throughout this evaluation period, the Core has significantly expanded the depth, breadth and cost-effectiveness of support for Center research. Examples include (1) new Citrix-based software deployment technologies that replace hundreds of software installations on individual workstations and provide secure, platform-independent, remote access to Core resourcess via the Internet and City of Hope intranet; (2) a new research and technology collaboration with the San Diego Supercomputing Center to pursue joint funding opportunities and host the Core's most computationally-intensive bioinformatics applications on the TeraGrid national supercomputing network; (3) development and delivery of more than 20 end-user training programs in collaboration with commercial software vendors and the National Center for Biotechnology Information (NCBI); and (4) funded participation in the caBIG Clinical Trials Management Systems (CTMS) workspace to develop workflows, information models and open-source software applications to facilitate Adverse Event (AE) reporting on a national scale. During FY 2006, the Core provided informatics support for 135 Cancer Center members; 76% of the users supported by biomedical informatics had peer-reviewed funding. Annual budget for the core is $2,065,231 (44% institutional, 3% user fees, 45% other), with 7% ($151,000) requested from the CCSG.

生物医学信息学核心成立于1998年，以满足信息管理的需求癌症中心的研究人员。核心提供广泛的硬件、软件和人员为许多研究人员和其他几个共享资源设施提供服务的资源。核心也适用于与希望之城和癌症中心治理委员会合作颁布标准，通过持续集成数据、数据库、应用程序来优化系统并最大限度地减少冗余和流程。在过去五年中，BIC 已成为使用最广泛的共享癌症中心资源和核心使用量每年都在持续增加。新的基于订阅的退款政策于 2003 年 10 月实施，退款收入从 2003 年的 7,250 美元增加到 66,700 美元 2006 年。自上次竞争性更新以来，超过 1/4 (276/1001) 的所有癌症中心都经过了同行评审出版物涉及信息学共享资源的使用。在整个评估期间，核心显着扩大了中心研究支持的深度、广度和成本效益。示例包括 (1) 基于 Citrix 的新软件部署技术，可取代数百种软件安装在各个工作站上，并提供对 Core 的安全、独立于平台的远程访问通过互联网和希望之城内联网获取资源；（2）新的研究和技术合作圣地亚哥超级计算中心寻求联合资助机会并举办核心最重要的会议 TeraGrid 国家超级计算网络上的计算密集型生物信息学应用； (3) 与商业机构合作开发和提供 20 多个最终用户培训计划软件供应商和国家生物技术信息中心 (NCBI)； (4) 资助参与在 caBIG 临床试验管理系统 (CTMS) 工作区中开发工作流程、信息模型和开源软件应用程序，以促进全国范围内的不良事件（AE）报告。 2006 财年期间，核心为 135 名癌症中心成员提供了信息学支持； 76%的用户由生物医学信息学支持并获得同行评审资金。核心的年度预算为 2,065,231 美元（44% 为机构费用，3% 用户费用，45% 其他费用），其中 7%（151,000 美元）由 CCSG 请求。