Our stories, our lives, our health: Refining an automated identification of HIV-negative, PrEP-eligible women in the emergency department

我们的故事、我们的生活、我们的健康：完善对急诊科 HIV 阴性且符合 PrEP 资格的女性的自动识别

• 批准号: 10021719
• 负责人: Amy Kristen Johnson
• 金额: $ 8.76万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-23 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10021719
• 关键词: AIDS prevention; Accident and Emergency department; Administrator; Area; Automation; Caring; Centers for Disease Control and Prevention (U.S.); Chicago; Cities; Clinic; Collaborations; Communities; Computerized Medical Record; Counseling; Data; Data Sources; Diagnosis; Education; Eligibility Determination; Emergency Care; Future; Geography; Goals; HIV; HIV Infections; HIV Seronegativity; HIV diagnosis; Health; Healthcare; Healthcare Systems; Heterosexuals; Individual; Infection; Intervention; Interview; Knowledge; Medical emergency; Medicine; Methods; Modeling; Newly Diagnosed; Not Hispanic or Latino; Patients; Performance; Populations at Risk; Prevalence; Prevention; Primary Health Care; Process; Provider; Public Health; Research Personnel; Risk; System; Techniques; Testing; Time; Triage; United States; Universities; Update; Woman; cisgender; cost; design; implementation research; improved; innovation; open source; pre-exposure prophylaxis; prevent; public health intervention; sex; social structure; structured data; uptake

PROJECT SUMMARY/ABSTRACT Pre-exposure prophylaxis, or PrEP, is a highly effective biomedical intervention to prevent HIV acquisition among at risk populations. PrEP offers an individual-controlled prevention method that is effective and safe. From 2014 to 2016, only 2% of women who have indication for PrEP received a prescription. Known individual level barriers to PrEP uptake among women include low rates of PrEP knowledge, low perceived risk of HIV acquisition, and barriers around how and where to access PrEP. Identification of women who may be at increased risk for HIV by healthcare systems is a key public health intervention that has potential to reduce new HIV infections. This study seeks to refine the automation of identification of PrEP-eligible cis-gender women using the electronic medical record system and other electronic open source and geospatial data through identifying commonalities among women newly diagnosed with HIV. As current quantitative indicators perform suboptimally, we will seek to establish commonalities among women with recent HIV infection to refine performance of the model. Using the Consolidated Framework for Implementation Research (CFIR), we will develop an implementation plan for utilization of the refined automated identification of HIV-negative, PrEP- eligible women in the emergency department. Improving identification of PrEP-eligible HIV-negative women in an emergency medical setting will likely influence uptake and is a low-cost, innovative solution to identification of potential PrEP-users. As strategies to increase PrEP uptake among women are under-studied, it is important to refine approaches for optimal performance.

项目概要/摘要 暴露前预防 (PrEP) 是一种预防 HIV 感染的高效生物医学干预措施 高危人群中。 PrEP 提供了一种有效且安全的个体控制预防方法。 2014年至2016年，只有2%有PrEP指征的女性收到了处方。已知个人 女性接受 PrEP 的障碍包括 PrEP 知识普及率低、艾滋病毒认知风险低 获取，以及如何以及在哪里获得 PrEP 的障碍。识别可能处于 医疗保健系统增加的艾滋病毒风险是一项关键的公共卫生干预措施，有可能减少 新的艾滋病毒感染。本研究旨在完善识别符合 PrEP 资格的顺性别的自动化 使用电子病历系统和其他电子开源数据和地理空间数据的妇女 通过识别新诊断出感染艾滋病毒的妇女的共性。作为目前的量化指标 如果表现不佳，我们将寻求在近期感染艾滋病毒的女性中建立共性，以改进 模型的性能。使用实施研究综合框架（CFIR），我们将 制定实施计划，利用 HIV 阴性、PrEP- 的精细自动识别 急诊科符合资格的女性。改善对符合 PrEP 资格的 HIV 阴性女性的识别 紧急医疗环境可能会影响采用率，并且是一种低成本、创新的识别解决方案 潜在的 PrEP 用户。由于提高女性 PrEP 接受率的策略尚未得到充分研究，因此 改进方法以实现最佳性能非常重要。

项目成果

Evaluation of multiple data sources for predicting increased need for HIV prevention among cisgender women: understanding missed opportunities for Pre-exposure Prophylaxis (PrEP).

• DOI: 10.1186/s12879-023-08719-6
• 发表时间: 2023-11-09
• 期刊: BMC INFECTIOUS DISEASES
• 影响因子: 3.7
• 作者: Johnson, Amy K.;Devlin, Samantha;Haider, Sadia;Oehler, Cassandra;Rivera, Juan;Alvarez, Isa;Ridgway, Jessica
• 通讯作者: Ridgway, Jessica