Administrative and Coordination Core

行政及协调核心

• 批准号: 10006150
• 负责人: Bruce T Lamb
• 金额: $ 43.54万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-30 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10006150
• 关键词: Accounting; Achievement; Address; Administrative Coordination; Administrator; Alzheimer' s Disease; Alzheimer' s disease model; Animal Model; Area; Benchmarking; Bioinformatics; Communication; Communities; Data; Development; Disease model; Doctor of Philosophy; Ensure; Evaluation; Extramural Activities; Feedback; Fostering; Generations; Goals; Grant; Head; Indiana; Laboratories; Leadership; Measures; Medicine; Mission; Modeling; Monitor; Oral; Peer Review; Phenotype; Preclinical Testing; Progress Reports; Publications; Recommendation; Reporting; Research; Research Personnel; Resources; Schedule; Speed; Staging; Time; TimeLine; United States National Institutes of Health; Universities; Work; cost; data management; data standards; data structure; improved; meetings; member; model development; neuroimaging; next generation; operation; programs; structured data; success; synergism; uptake

PROJECT SUMMARY ADMINISTRATIVE (ADMIN) CORE The Administration (ADMIN) Core of the Indiana University (IU)/Jackson Laboratory (JAX) Alzheimer's Disease Precision Models Center (IU/JAX ADPMC), led by ADMIN Head Dr. Bruce Lamb at IU and with assistance from multiple Principle Investigators (mPIs) Dr. Paul Territo at IU and Drs. Greg Carter and Gareth Howell at JAX, along with the support of two PhD-level Program co-Managers and full-time administrators at both IU and JAX, will oversee all administrative and scientific functions of the Center. The ADMIN Core will execute these duties with oversight from an External Advisory Board (EAB), composed of leading experts in the field, and a Center Steering Committee (CSC), composed of the PIs, research leaders at both IU and JAX, and program officials from the NIH. The EAB will convene biannually and the CSC monthly to review progress and provide input and feedback (oral and written) to ensure that the IU/JAX ADPMC (1) achieves its mission, aims, milestones and metrics; (2) effectively deals with any unanticipated problems or concerns; and (3) adapts to likely experimental and technical advances in the field. There will be weekly ADMIN meetings and monthly Core and Project meetings. These will be focused on issues unique to specific Cores/Project while ensuring maximal synergy between the various components of the IU/JAX ADPMC. Close interaction will be fostered among the Bioinformatics and Data Management Core, the Preclinical Testing Core and the Disease Model Development and Phenotyping Project, thus facilitating the speed of discovery while reducing overall cost. One of the primary goals of the ADMIN Core will be to ensure that discoveries made in one area of the ADPMC will benefit the whole, leading to efficiencies in time and cost. Finally, the ADMIN Core will also promote interactions and meetings of the IU/JAX ADPMC with other ongoing research efforts in the Alzheimer's research community, including the NIA-supported ADCs/ADRCs, the Alzheimer's Disease Neuroimaging Initiative (ADNI), Alzheimer's Disease Accelerating Medicine's Partnership (AD-AMP), and the Alzheimer's Disease Sequencing Project (ADSP). The Specific Aims of the IU/JAX ADPMC ADMIN Core are: 1. Provide effective and efficient management, oversight and evaluation of the IU/JAX ADPMC and interactions with the AD research community. 2. Ensure timely and successful completion of all project and core aims and milestones. 3. Facilitate interactions between and among the Bioinformatics and Data Management Core, the Preclinical Testing Core and the Disease Model Development and Phenotyping Project. !

项目摘要 行政 (ADMIN) 核心 印第安纳大学 (IU)/杰克逊实验室 (JAX) 阿尔茨海默病管理 (ADMIN) 核心 疾病精确模型中心 (IU/JAX ADPMC)，由 IU 的 ADMIN 负责人 Bruce Lamb 博士领导，并与 来自印第安纳大学的多位主要研究者 (mPI) 的 Paul Territo 博士和 Drs. 的协助。格雷格·卡特和 JAX 的 Gareth Howell 以及两位博士级项目联合经理和全职人员的支持 IU 和 JAX 的管理员将监督该中心的所有行政和科学职能。 管理核心将在外部顾问委员会 (EAB) 的监督下执行这些职责， 由该领域的顶尖专家组成，以及由 PI 组成的中心指导委员会 (CSC)， IU 和 JAX 的研究领导者以及 NIH 的项目官员。 EAB 将召开 每半年一次，CSC 每月一次，审查进展情况并提供意见和反馈（口头和书面） 确保 IU/JAX ADPMC (1) 实现其使命、目标、里程碑和指标； (2) 有效 处理任何意外的问题或疑虑； (3) 适应可能的实验和技术 该领域的进展。每周举行管理员会议，每月举行核心和项目会议。 这些将重点关注特定核心/项目特有的问题，同时确保最大的协同作用 IU/JAX ADPMC 的各个组件之间。双方将加强密切互动 生物信息学和数据管理核心、临床前测试核心和疾病模型 开发和表型项目，从而加快发现速度，同时降低总体成本。 ADMIN 核心的主要目标之一是确保在某一领域取得的发现 ADPMC 将使整体受益，从而提高时间和成本效率。最后，ADMIN Core 还将 促进 IU/JAX ADPMC 与其他正在进行的研究工作的互动和会议 阿尔茨海默病研究团体，包括 NIA 支持的 ADC/ADRC、阿尔茨海默病 神经影像计划 (ADNI)、阿尔茨海默病加速医学合作伙伴关系 (AD-AMP) 和 阿尔茨海默病测序项目（ADSP）。 IU/JAX ADPMC ADMIN 核心的具体目标是： 1. 为 IU/JAX ADPMC 提供有效且高效的管理、监督和评估 以及与 AD 研究界的互动。 2. 确保及时、成功完成所有项目以及核心目标和里程碑。 3. 促进生物信息学和数据管理核心、生物信息学和数据管理核心之间的互动 临床前测试核心以及疾病模型开发和表型分析项目。 ！