Office of the Scientific Director

科学主任办公室

• 批准号: 10021346
• 负责人: Susan Amara
• 金额: $ 392.57万
• 依托单位: NATIONAL INSTITUTE OF MENTAL HEALTH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10021346
• 关键词: Adult; Affective; Anxiety; Anxiety Disorders; Area; Attention; Attention deficit hyperactivity disorder; Attentional deficit; Awareness; Basic Science; Behavior; Behavioral; Big Data; Bipolar Disorder; Brain; Brain imaging; Capital; Child; Clinical; Clinical Research; Cognition; Cognitive; Complement; Computer Simulation; Congresses; Data Analytics; Data Storage and Retrieval; Diagnosis; Doctor of Philosophy; Educational workshop; Ensure; Environment; Epidemiology; Ethics; Extramural Activities; Fostering; Functional Imaging; Functional Magnetic Resonance Imaging; Funding Mechanisms; Genetic; Hyperactive behavior; Institutes; Intramural Research Program; Investigational Therapies; Leadership; Learning; Location; Machine Learning; Magnetic Resonance Spectroscopy; Magnetoencephalography; Mediating; Memory; Mental Depression; Mental Health; Mental disorders; Mission; Molecular; Mood Disorders; Motivation; National Institute of Mental Health; Nervous system structure; Neurosciences; Opioid; Peptides; Prevention; Principal Investigator; Psychology; Public Health; Recovery; Research; Research Activity; Research Personnel; Research Project Grants; Research Subjects; Research Training; Resources; Role; Schizophrenia; Science; Scientist; Series; Synapses; System; Thinking; Time; Training; Translational Research; United States National Institutes of Health; Women' s Health; autism spectrum disorder; brain behavior; clinical care; clinical development; clinical investigation; depressive symptoms; experience; imaging genetics; innovation; interest; member; mental disorder prevention; molecular imaging; monoamine; neurofeedback; neuronal circuitry; new technology; novel; novel strategies; tenure track

The NIMH Division of Intramural Research Programs' (IRP) scientists conduct research ranging from studies into the mechanisms of normal brain function at the behavioral, systems, cellular, and molecular levels, to clinical investigations into the diagnosis, treatment and prevention of mental illness. Researchers study conditions in adults and children such as anxiety, depressive, bipolar, attention deficit hyperactivity, and autism spectrum disorders, as well as schizophrenia. Approaches include experimental therapeutics; functional and molecular imaging; genetics; behavioral, cognitive, molecular and cellular neuroscience; and epidemiology. In part, because of its state-of-the-art facilities, unique funding mechanisms, and location in the nation's capital, the IRP is viewed as a national resource, providing unique opportunities in mental health research and research training. Susan G. Amara, Ph.D., serves as the Scientific Director for the NIMH IRP and provides oversight to a diverse mental health research portfolio that includes clinical projects on autism, women's health, depression, bipolar disorder, schizophrenia, attention deficit hyperactivity disorder, mood and anxiety disorders; and basic projects geared toward answering fundamental questions related to mental health in the areas of cognition, genetics, learning and memory, and behavior. The portfolio also includes projects aimed at exploring new technologies and approaches to neuroscience such as functional Magnetic Resonance Imaging (fMRI), Magnetic Resonance Spectroscopy (MRS) and Magnetoencephalography (MEG). The Scientific Director provides supplemental resources, as appropriate, to research projects in the IRP portfolio. In FY2019, a new tenure-track principal investigator joined the IRP whose group will study the role of opioid and monoamine systems in regulating synaptic integration in neuronal circuits that mediate motivation and affective states. In addition, we hired a Scientific Information Officer (SIO) to provide support for big data storage and analytics. The Office of the Scientific Director (OSD) continued to support collaborative activities within NIMH and with other NIH institutes, including collaborative research projects involving three or more PIs, and several scientific workshops and seminar series, for example, workshops on topics such as real-time fMRI neurofeedback, attention and awareness, regulatory peptides, and computational modeling of the nervous system; and a seminar series on machine learning in brain imaging, neuroscience, and psychology. The OSD also continued to host the seminar series called, "New Discoveries in Mental Health Research." The purpose of the seminar series is to help intramural scientists to learn more about innovative extramural research that is relevant to the NIMH mission, and to build new relationships with investigators outside of the Intramural Research Program.

NIMH的壁内研究计划（IRP）科学家进行研究，从研究到行为，系统，细胞和分子水平正常大脑功能的机制，再到对精神疾病诊断，治疗和预防的临床研究。研究人员研究成人和儿童的条件，例如焦虑，抑郁，双相情感，注意力缺陷多动和自闭症谱系障碍以及精神分裂症。方法包括实验治疗；功能和分子成像；遗传学；行为，认知，分子和细胞神经科学；和流行病学。在某种程度上，由于其最先进的设施，独特的资金机制和在美国首都的地理位置，IRP被视为国家资源，为心理健康研究和研究培训提供了独特的机会。 Susan G. Amara博士担任NIMH IRP的科学总监，并为多样化的心理健康研究组合提供了监督，其中包括有关自闭症，妇女健康，抑郁症，双相情感障碍，精神分裂症，注意力缺陷多动态障碍，情绪和焦虑症的临床项目；以及旨在回答认知，遗传学，学习，记忆以及行为领域中与心理健康有关的基本问题的基本项目。该投资组合还包括旨在探索新技术和神经科学方法的项目，例如功能性磁共振成像（fMRI），磁共振光谱（MRS）和磁脑摄影（MEG）。科学总监为IRP投资组合中的研究项目提供了补充资源。 在2019财年，一名新的终身制主要研究人员加入了IRP，其小组将研究阿片类和单胺系统在调节介导动机和情感状态的神经元电路中的突触整合中的作用。此外，我们聘请了一名科学信息官员（SIO）来为大数据存储和分析提供支持。 The Office of the Scientific Director (OSD) continued to support collaborative activities within NIMH and with other NIH institutes, including collaborative research projects involving three or more PIs, and several scientific workshops and seminar series, for example, workshops on topics such as real-time fMRI neurofeedback, attention and awareness, regulatory peptides, and computational modeling of the nervous system;以及关于脑成像，神经科学和心理学中机器学习的研讨会系列。 OSD还继续举办研讨会系列，称为“心理健康研究中的新发现”。研讨会系列的目的是帮助壁内科学家更多地了解与NIMH任务相关的创新外壁外研究，并与壁内研究计划以外的研究人员建立新的关系。