Emory-Georgia Clean Air Research & Education (CARE) Program

埃默里-佐治亚州清洁空气研究

• 批准号: 10017980
• 负责人: Carla J Berg
• 金额: $ 24.14万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-13 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10017980
• 关键词: Address; Adult; Affect; Air; Air Pollution; Applied Research; Centers for Disease Control and Prevention (U.S.); Cessation of life; Child; Collaborations; Country; Education; Environment; Environmental Exposure; Environmental Hazards; Environmental Health; Funding; Goals; Grant; Health; Indoor Air Pollution; Infrastructure; Institution; Joints; Medical; Mentors; Mentorship; Molecular; Morbidity - disease rate; National Institute of Environmental Health Sciences; Policies; Pollution; Population; Positioning Attribute; Public Health; Reporting; Research; Research Training; Time; Training; Training Programs; Universities; Western Asia Georgia; Woman; ambient air pollution; attributable mortality; burden of illness; education research; environmental tobacco smoke; environmental tobacco smoke exposure; global health; indexing; knowledge translation; low and middle-income countries; men; mortality; programs; public health priorities; ranpirnase; research data dissemination; smoke-free policy; smoking prevalence; statistics; training opportunity

SUMMARY/ABSTRACT Globally, 7 million deaths are attributable to the joint effects of indoor and ambient air pollution annually, with ~94% occurring in low- and middle-income countries (LMICs). In addition, secondhand smoke (SHS) is a major global health problem, causing ~600,000 deaths (1% of mortality) annually, with women and children being disproportionately affected by SHS. LMICs are also disproportionately impacted by SHS and related morbidity and mortality. The Republic of Georgia (GE) is notably impacted by air pollution and SHS. Adverse environmental exposures cause 21% of disease burden and 25% of deaths, including 30% of disease burden and 14% of deaths among children. Moreover, GE’s mortality index attributed to ambient and indoor air pollution is the 3rd highest in the world. Additionally, the smoking prevalence in GE is 58% in men (6th highest in the world) and 6% in women, implying significant impact of SHS in GE. Indeed, 42% of GE adults report daily SHS exposure. Underscoring the impact of these statistics, GE’s 2017-2021 National Environment and Health Action Plan indicates that addressing air pollution is among the most prominent public health priorities in GE. However, there is limited in-country capacity to conduct research regarding the impact of such environmental hazards on health. This application, the Emory-Georgia Clean Air Research and Education (EG-CARE) program, coincides with increased prioritization of research and policy to reduce air pollution and address NCDs in GE, and represents a uniquely strategic collaboration among Emory University, the GE National Center for Disease Control and Public Health (NCDC), the GE National Environmental Agency (NEA), and Tbilisi State Medical University (TSMU). Various existing collaborations and ongoing efforts will be leveraged, including Fogarty-funded grants to promote smoke-free air policies in GE (an R01) and to enhance TB research capacity in GE (a D43), as well as an NIEHS-funded center grant called HERCULES (a P30) and an NIEHS-funded T32 training program at Emory. Key leaders of these efforts and across these institutions will collaborate to implement this training program, with the long-term goal of enhancing capacity in GE to conduct research related to NCDs and environmental health (EH) and ultimately inform policy and practice to reduce NCDs. The overall objective of this application is to develop and implement a training program involving training, mentorship, and applied research opportunities to ultimately reach the long-term goal. Thematically, EG-CARE will focus on the intersection between NCDs and EH, particularly air pollution, and aim to: 1) enhance formal NCD and EH training opportunities and institutional infrastructure to support ongoing research training; 2) provide mentored NCD- and EH- related research opportunities spanning from the molecular to the population level, with a particular focus on air quality and pollution, to candidates with outstanding potential; and 3) emphasize research dissemination and knowledge translation to inform policy and practice. Leveraging the aforementioned ongoing efforts, this proposal addresses a timely, high-priority public health concern in GE, underscoring its potential impact. The program team is uniquely positioned to address these aims and enhance research capacity related to NCDs and EH in the next 5 years and in the long term.

摘要/摘要 全球每年有 700 万人死于室内和环境空气污染的共同影响，其中约 94% 此外，二手烟 (SHS) 是一种主要的全球健康问题。 每年导致约 600,000 人死亡（占死亡率的 1%），其中妇女和儿童受到的影响尤为严重 中低收入国家也受到二手烟及相关发病率和死亡率的影响。 乔治亚州 (GE) 受到空气污染和二手烟的严重影响，21% 的疾病是由不良环境暴露引起的。 负担和 25% 的死亡，其中包括 30% 的疾病负担和 14% 的儿童死亡。 环境和室内空气污染指数位居世界第三。此外，吸烟率位居世界第三。 GE 在男性中占 58%（全球排名第六），在女性中占 6%，这意味着 SHS 对 GE 的影响确实很大，占 42%。 GE 成人每天报告二手烟暴露情况，强调了这些统计数据的影响，GE 的 2017-2021 年国家环境报告。 健康行动计划表明，解决空气污染问题是 GE 最重要的公共卫生优先事项之一。 然而，国内开展有关此类环境危害对人类的影响的研究的能力有限。 此应用程序即埃默里-佐治亚州清洁空气研究和教育 (EG-CARE) 计划，与 GE 更加重视减少空气污染和解决非传染性疾病的研究和政策，并代表了独特的 埃默里大学、GE 国家疾病控制和公共卫生中心 (NCDC) 之间的战略合作， GE国家环境局（NEA）和第比利斯国立医科大学（TSMU） 将利用合作和持续努力，包括福格蒂资助的赠款来推广无烟空气政策 GE（R01）和增强 GE（D43）的结核病研究能力，以及 NIEHS 资助的中心拨款，称为 HERCULES（P30）和 NIEHS 资助的埃默里大学 T32 培训项目是这些努力的主要领导者。 各机构将合作实施该培训计划，其长期目标是增强 GE 的能力 开展与非传染性疾病和环境健康 (EH) 相关的研究，并最终为政策和实践提供信息，以减少 该应用程序的总体目标是开发和实施涉及培训的培训计划， EG-CARE 将重点关注指导和应用研究机会，以最终实现长期目标。 关于非传染性疾病和 EH 之间的交叉点，特别是空气污染，目标是： 1) 加强正式的 NCD 和 EH 培训 支持正在进行的研究培训的机会和机构基础设施；2) 提供受指导的非传染性疾病和 EH- 从分子水平到人口水平的相关研究机会，特别关注空气质量 和污染，对具有突出潜力的候选人；3）强调研究传播和知识； 利用当前的努力，本提案提出了及时、有效的建议。 GE 高度重视的公共卫生问题，强调了该项目团队具有独特的潜在影响。 实现这些目标，并在未来 5 年和长期内增强与非传染性疾病和 EH 相关的研究能力。