Predictors and consequences of young adult marijuana use and concurrent and simultaneous alcohol use: Month to month variation across 24 consecutive months

年轻人吸食大麻以及并发和同时饮酒的预测因素和后果：连续 24 个月的月度变化

• 批准号: 10017790
• 负责人: CHRISTINE M. Lee
• 金额: $ 24.62万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-15 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10017790
• 关键词: 21 year old; Acute; Adopted; Adult; Affect; Age; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Communities; Consumption; Data; Data Analyses; Data Set; Enrollment; Epidemiology; Etiology; Evaluation Studies; Event; Frequencies; Funding; Future; Health; Health Policy; Impulsivity; Individual; Intervention; Knowledge; Laws; Lead; Legal; Life; Longitudinal Studies; Marijuana; Mental Health; Motivation; National Institute on Alcohol Abuse and Alcoholism; Outcome; Pattern; Policies; Prevalence; Preventive Intervention; Public Health; Publishing; Reporting; Research; Research Design; Risk; Role; Sampling; Time; Variant; Washington; aged; alcohol consequences; alcohol related consequences; base; binge drinking; biological sex; college; cost efficient; drinking; experience; innovation; longitudinal dataset; marijuana legalization; marijuana use; marijuana user; minimum drinking age; novel; physical conditioning; problem drinker; prospective; recruit; secondary analysis; young adult

ABSTRACT Alcohol and marijuana are the most commonly used substances among young adults (YAs) and their use is often intertwined. With recent changes in legalization of marijuana in several states, it is critical to understand the impact marijuana use may have on alcohol use. In states like Washington where both alcohol and recreational marijuana use are legal for adults (aged 21+), it is important to examine how these two substances are being used and interacting among YAs. Increases in marijuana use may be associated with decreases in alcohol use if marijuana acts as a substitute for alcohol, or it may lead to greater alcohol use if there are complementary effects such that both marijuana and alcohol use increase over time. To date, most study designs have not provided data to allow examination, at the individual level, of whether there are prospective month-to-month substitution or complementary effects over time and there are no studies to date that have examined these effects in the context of legalized marijuana. Also, there is limited research with respect to short-term consequences of different patterns of overlapping marijuana and alcohol use. Simultaneous alcohol and marijuana (SAM; i.e., on the same occasion so the effects overlap) use is associated with particular acute risks including serious legal, academic, interpersonal, physical and mental health problems. However, most alcohol users who use marijuana do so simultaneously. The present application proposes to conduct secondary analyses from a cutting-edge longitudinal study of YAs recruited from the community in WA State during the time of legalized marijuana. Project Transitions (R01AA022087) collected monthly data across 24 consecutive months from YAs (ages 18-25 over the course of the study). YAs (N=779) between ages 18 and 23 who reported consuming at least one alcoholic drink in the prior year were recruited and enrolled into Project Transitions. This NIAAA-funded study focused on alcohol use; however, a rich set of data on monthly marijuana use, SAM use, and related consequences is also available. The present application proposes secondary data analysis of this unique longitudinal dataset. Findings from this cost- efficient secondary analysis study utilizing monthly data will allow us to answer innovative and critically important questions that increase our knowledge of the co-occurrence of alcohol and marijuana use, whether marijuana may have substitution or complementary effects with alcohol, associations between concurrent and SAM use with short-term consequences and how these consequences may influence future use and how important naturally occurring life events (i.e., turning 21) influence trajectories of use. The project will provide answers to novel research questions that are of public health and policy importance and have important implications for young adult prevention and intervention strategies.

抽象的 酒精和大麻是年轻人 (YAs) 最常用的物质，其使用是 经常交织在一起。随着最近几个州大麻合法化的变化，了解这一点至关重要 吸食大麻可能对饮酒产生影响。在像华盛顿这样的州，酒精和 娱乐性大麻的使用对于成年人（21 岁以上）来说是合法的，重要的是要检查这两者如何 物质正在 YA 之间使用并相互作用。大麻使用量的增加可能与 如果大麻作为酒精的替代品，则饮酒量会减少，或者如果以下情况，可能会导致饮酒量增加： 随着时间的推移，大麻和酒精的使用都会增加，这是互补的。迄今为止，大多数 研究设计尚未提供数据以允许在个人层面上检查是否存在 随着时间的推移，预期的逐月替代或补充效应，迄今为止还没有研究 他们在大麻合法化的背景下研究了这些影响。此外，关于 尊重大麻和酒精重叠使用的不同模式的短期后果。 同时使用酒精和大麻（SAM；即在同一场合，因此效果重叠）是 与特别严重的风险相关，包括严重的法律、学术、人际、身体和精神风险 健康问题。然而，大多数吸食大麻的酗酒者同时吸食大麻。现在的 申请建议对招募的青年学生进行前沿纵向研究进行二次分析 在大麻合法化期间来自西澳州社区的。项目过渡 (R01AA022087) 收集了连续 24 个月的青少年（研究过程中 18-25 岁）的月度数据。青少年 (N=779) 年龄在 18 岁至 23 岁之间且报告在上一年至少饮用过一杯酒精饮料的人 招募并加入项目过渡。这项由 NIAAA 资助的研究重点关注酒精使用情况；然而，一个 还提供有关每月大麻使用、SAM 使用以及相关后果的丰富数据。现在的 应用程序建议对这个独特的纵向数据集进行二次数据分析。从这个成本中得出的结论是—— 利用每月数据进行有效的二次分析研究将使我们能够以创新和批判性的方式回答 增加我们对酒精和大麻同时使用的认识的重要问题，是否 大麻可能与酒精具有替代或补充作用，同时和之间的关联 SAM 使用带来的短期后果以及这些后果如何影响未来的使用以及如何影响 重要的自然发生的生活事件（例如，21 岁）会影响使用轨迹。该项目将提供 对具有公共卫生和政策重要性且具有重要意义的新颖研究问题的答案 对年轻人预防和干预策略的影响。