Intensive Daily Measurement of Simultaneous Alcohol and Marijuana Use in a High-Risk Community Sample of Young Adults: Impacts on Acute and Longer-term Use and Consequences

对高风险社区年轻人样本中同时使用酒精和大麻的每日强化测量：对急性和长期使用的影响及后果

• 批准号: 9753831
• 负责人: CHRISTINE M. Lee
• 金额: $ 48.3万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-01 至 2021-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9753831
• 关键词: 21 year old; Acute; Address; Adult; Affect; Alaska; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Area; Attention; Attitude; Behavioral; Car Phone; Colorado; Communities; Consequentialism; Data; Data Analytics; District of Columbia; Driving While Intoxicated; Feeling; Gender; Health; Health Care Costs; High Prevalence; Individual; Injury; Intoxication; Knowledge; Lead; Legal; Marijuana; Measurement; Mental Health; Modeling; Motivation; National Institute on Alcohol Abuse and Alcoholism; Oregon; Pattern; Perception; Policies; Population; Prevalence; Public Health; Reporting; Risk; Sampling; Statutes and Laws; Techniques; Testing; Time; Traffic accidents; United States; Voice; Washington; Youth; aged; alcohol consequences; alcohol research; automobile accident; base; binge drinking; college; coping; demographics; drinking; hangover; high risk; intervention program; marijuana legalization; marijuana use; marijuana user; physical conditioning; public policy on alcohol; response; risk perception; social; therapy design; young adult

ABSTRACT Major changes in marijuana legislation are likely to affect not only the use of marijuana, but also the use of other substances including alcohol. Alcohol and marijuana are psychoactive substances commonly used by young adults in the US and are independently associated with numerous acute and long-term consequences. To date, recreational marijuana use has been legalized for adults age 21+ in four states (Washington, Colorado, Oregon, and Alaska) and the District of Columbia, with numerous states currently debating similar legislation. These policy changes have shifted attention to the important individual and public health implications of simultaneous alcohol and marijuana (SAM) use, and potential additive or synergistic negative effects and consequences (e.g., increased risk of driving while intoxicated, fatal car accidents). Among youth and adults, clear patterns are emerging; perceptions of the harmfulness of marijuana use are decreasing and the prevalence of marijuana use is increasing. Further, it is clear that SAM use is common among youth and young adults. Given the public health costs associated with alcohol use, there is a pressing need to understand the ways in which SAM use may have complementary effects (both alcohol and marijuana use increase) or substitution effects (amount of alcohol use decreases when used with marijuana), as well as the extent to which SAM use is associated with increases in acute and longer-term consequences of alcohol use. To date, very little is known regarding how SAM use differs from use of either substance alone on a given occasion. The current application proposes to collect and analyze intensive data collected twice daily via mobile phones for 16 weeks (using interactive voice response) across two years and longitudinal data collected annually online across three years from a high-risk community sample of young adult SAM users, aged 18-25, in the state of Washington. Specific aims of this application are to: 1) examine whether SAM use poses additional alcohol- related risks, compared to using alcohol without marijuana, at the daily level; 2) understand the motivations, intentions, and situations that make SAM use more likely and more consequential among young adults; 3) model the longitudinal patterns of SAM use and associations with health consequences across 3 years; and 4) examine potential moderators of these relationships. The proposed study will examine SAM use in a state where marijuana is legal and the observed effects will add knowledge about the effects of marijuana on alcohol use and related health consequences among young adults in the US.

抽象的 大麻立法的重大变化可能不仅会影响大麻的使用，还会影响大麻的使用。 其他物质，包括酒精。酒精和大麻是人们常用的精神活性物质 美国的年轻人，并且与许多急性和长期后果独立相关。 迄今为止，四个州（华盛顿州、华盛顿州、 科罗拉多州、俄勒冈州和阿拉斯加）和哥伦比亚特区，许多州目前正在讨论类似的问题 立法。这些政策变化将注意力转向重要的个人和公共卫生 同时使用酒精和大麻 (SAM) 的影响，以及潜在的累加或协同负面影响 影响和后果（例如，醉酒驾驶、致命车祸的风险增加）。青年之中 对于成年人来说，清晰的模式正在出现；人们对吸食大麻危害性的认识正在下降 吸食大麻的现象正在增加。此外，很明显，SAM 的使用在青少年和青少年中很常见。 年轻人。鉴于与饮酒相关的公共卫生成本，迫切需要了解 SAM 的使用方式可能会产生互补效应（酒精和大麻的使用都会增加）或 替代效应（与大麻一起使用时饮酒量减少），以及程度 SAM 的使用与酒精使用的急性和长期后果的增加有关。迄今为止， 关于 SAM 的使用与在特定场合单独使用任何一种物质有何不同，人们知之甚少。这 当前的应用程序建议收集和分析每天两次通过手机收集的密集数据 两年内 16 周（使用交互式语音应答），每年在线收集纵向数据 三年来，我们对美国州 18-25 岁的年轻 SAM 用户的高风险社区样本进行了研究 华盛顿。本申请的具体目的是：1) 检查 SAM 的使用是否会产生额外的酒精- 与每天饮酒但不吸大麻相比，存在相关风险； 2）了解动机， 使年轻人更有可能使用 SAM 且影响更大的意图和情况； 3） 对 3 年内 SAM 使用的纵向模式及其与健康后果的关联进行建模；和 4) 检查这些关系的潜在调节者。拟议的研究将考察 SAM 在某个州的使用情况 在大麻合法的地方，观察到的影响将增加人们对大麻对酒精影响的了解 美国年轻人的使用和相关健康后果。