Kentucky Center for Clinical and Translational Science

肯塔基州临床和转化科学中心

基本信息

批准号：
9314011
负责人：
Philip A Kern
金额：
$ 364.53万
依托单位：
UNIVERSITY OF KENTUCKY
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-08-15 至 2020-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9314011
关键词：
Abbreviations Academic Medical Centers Affect Agriculture Appalachian Region Arts Clinical Clinical Research Clinical Sciences Clinical Trials Clinical Trials Network Collaborations Communities Data Development Discipline Diverse Workforce Education Engineering Environment Fostering Future Goals Health Healthcare Healthcare Systems Home environment Informatics Institutes Institution Interdisciplinary Study Kentucky Lead Leadership Longevity Marshal Medical center Methodology Mission Multi-Institutional Clinical Trial Participant Personal Satisfaction Phase Population Positioning Attribute Quality of life Research Research Training Role Rural Rural Community Rural Population Scholarship Science Solid Target Populations Translational Research Trust Universities West Virginia Work Workforce Development abstracting base biomedical informatics catalyst collaborative environment college data management drug development food environment health care quality health care service organization health disparity healthcare community improved innovation medical schools medically underserved meetings named group novel novel therapeutics programs success

项目摘要

Contact PD/PI: Kern, Philip A PROJECT SUMMARY The University of Kentucky (UK) Center for Clinical and Translational Science (CCTS) has created an integrated home for clinical and translational research to promote scientific progress and discoveries at every phase of the translational continuum. The CCTS has fundamentally transformed the research environment not only at UK but throughout Central Appalachia through the development of a strong research network, the Appalachian Translational Research Network (ATRN), with integrated research partnerships including other CTSA hubs. When combined with an in-depth understanding of the unique and serious health challenges faced by Central Appalachian residents, the UK CCTS is positioned to lead local, regional and national research efforts that focus on the significant health disparities in this population. Our overarching goal as a CTSA hub is to continue to champion innovation in the full spectrum of clinical and translational research while educating the workforce of the future, engaging our communities in biomedical science and working with the national network to advance cohesive multi-center clinical trials, which will ultimately elevate the health and quality of life of the populace of Central Appalachia. Specifically, the UK CCTS will: 1) Lead institutional innovation in the delivery of efficient, effective clinical and translational research. 2) Develop a diverse workforce across multiple disciplines that advances translational research and excels in team-based science. 3) Meet the unique needs of Central Appalachian residents by extensively engaging and collaborating with our regional, rural and community-based partners. 4) Catalyze innovative research, including novel drug development and informatics methodologies, with particular focus on bringing innovation to special populations and across the lifespan. 5) Create an efficient clinical trials network, centered at UK, and extending into our partner health care systems that will be an essential and leading component of the CTSA consortium, involving participants throughout a four state region of rural Central Appalachia. The UK CCTS benefits from a collaborative environment found on only a few university campuses. UK has 16 colleges, with 11 involved in the UK CCTS (including six biomedical colleges) on one central campus. This physical proximity of our academic and health care communities, along with a culture of collaboration, creates a closely knit unified academic community and positions the UK CCTS to demonstrate the impact of collaborative translational research and leadership in team science. Our efforts have already been successful at transforming the culture of the UK academic medical center to one that more keenly appreciates scholarship, innovation and translational science. We now plan to build on these strengths to advance translational science to the next level, with further development of our clinical trial networks, development of novel informatics programs, and continued development of the workforce throughout the region. These efforts will benefit the medically underserved residents of Central Appalachia and will significantly contribute to the national CTSA program. 1 Project Summary/Abstract Page 287 Contact PD/PI: Kern, Philip A

联系人 PD/PI：Kern, Philip A 项目概要肯塔基大学（英国）临床和转化科学中心 (CCTS) 创建了一个临床和转化研究的综合家园，以促进每个领域的科学进步和发现 CCTS 并没有从根本上改变研究环境通过发展强大的研究网络，不仅在英国，而且在整个阿巴拉契亚中部，阿巴拉契亚转化研究网络 (ATRN)，拥有综合研究伙伴关系，包括其他 CTSA 中心与对独特且严重的健康挑战的深入了解相结合。面对阿巴拉契亚中部居民，英国 CCTS 定位于领导地方、区域和国家我们的总体目标是关注这一人群的重大健康差异。 CTSA 中心将继续倡导全方位临床和转化研究的创新，同时教育未来的劳动力，让我们的社区参与生物医学科学并与国家网络推进有凝聚力的多中心临床试验，这最终将提高健康和阿巴拉契亚中部民众的生活质量。具体而言，英国 CCTS 将：1) 领导机构提供高效、有效的临床和转化研究的创新。2) 发展多元化跨多个学科的劳动力，推动转化研究并在基于团队的科学方面表现出色。 3) 通过与我们的广泛接触和合作，满足阿巴拉契亚中部居民的独特需求区域、农村和社区合作伙伴 4) 促进创新研究，包括新药。发展和信息学方法，特别注重为特殊人群带来创新 5) 创建一个以英国为中心，并延伸到我们国家的高效临床试验网络。合作伙伴医疗保健系统将成为 CTSA 联盟的重要和主要组成部分，包括整个阿巴拉契亚中部农村地区的四个州的参与者。英国 CCTS 受益于只有少数大学校园存在协作环境英国有 16 所学院，其中 11 所参与其中。英国 CCTS（包括六所生物医学学院）位于一个中心校区，地理位置非常接近。学术界和医疗保健界以及合作文化共同创造了一个紧密团结的社区学术界并让英国 CCTS 展示协作转化的影响团队科学的研究和领导。我们的努力已经成功地改变了文化。英国学术医学中心的一个更热衷于学术、创新和我们现在计划利用这些优势将转化科学推进到下一个阶段。随着我们的临床试验网络的进一步发展、新型信息学项目的开发，以及整个地区劳动力的持续发展。这些努力将有利于医疗行业阿巴拉契亚中部服务不足的居民，将为国家 CTSA 计划做出重大贡献。 1 项目总结/摘要第287页联系人 PD/PI：Kern, Philip A