Kentucky Center for Clinical and Translational Science

肯塔基州临床和转化科学中心

• 批准号: 10681386
• 负责人: Philip A Kern
• 金额: $ 331.99万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10681386
• 关键词: Academic Medical Centers; Acceleration; Address; Agriculture; Appalachian Region; Award; COVID-19 pandemic; Cardiovascular system; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Complement; Computer software; Dedications; Development; Diabetes Mellitus; Discipline; Distress; Economics; Engineering; Environment; Epidemic; Fostering; Funding; Future; Generations; Grant; Growth; Health; Health Sciences; Health Status; Healthcare; Home; Institution; Integrated Health Care Systems; Intervention; Investments; Kentucky; Lead; Longevity; Malignant Neoplasms; Medical; Medical center; Mission; Modeling; National Center for Advancing Translational Sciences; Neurosciences; Obesity; Participant; Patients; Persons; Phase; Policies; Population; Positioning Attribute; Quality of life; Reporting; Research; Resources; Rural; Rural Community; Rural Health; Science; Sports; Substance Use Disorder; Substance abuse problem; Translational Research; Translations; Underserved Population; United States; Universities; West Virginia; Work; austin; clinical center; clinical research site; collaborative environment; college; community based participatory research; community engagement; diversity and inclusion; health disparity; health equity; health inequalities; improved; innovation; inter-institutional; new technology; opioid abuse; patient engagement; programs; recruit; response; rural area

Contact PD/PI: Kern, Philip A. PROJECT SUMMARY – OVERALL The University of Kentucky (UK) Center for Clinical and Translational Science (CCTS) has created an integrated home for clinical and translational research which promotes scientific progress and discoveries at every phase of the translational continuum. The CCTS has partnered with communities in Central Appalachia to address multiple generations of recalcitrant health inequities related in part to the economic distress of rural communities. The CCTS has fundamentally transformed UK and Central Appalachia through the development of strong academic-community research networks and collaborations within the CTSA consortium. Appalachian health disparities are further magnified by the opioid and substance abuse epidemic, which has greatly impacted eastern Kentucky and West Virginia. The strong UK research portfolio puts the UK CCTS in an optimal position to lead local, regional and national research efforts focused on rural health inequities. The aligned missions of UK, UK HealthCare and the CCTS focus on achieving health equity by engaging in highly innovative, collaborative and dynamic translational research to address rural health needs. The CCTS will continue to educate the translational workforce of the future, engage rural communities in translational and bi-directional team science and work with the national network to advance transdisciplinary research and clinical trials through the following Specific Aims: 1) develop, innovate and transform our research environment to promote impactful science and discovery within our integrated health care system to meet the unique health needs of Central Appalachian residents; 2) lead institutional innovation in the delivery of impactful clinical and translational research that covers the lifespan, fully engages the community and embraces team science; 3) catalyze an efficient, university-wide clinical trials organization which adds value to the CTSA consortium by engaging participants from rural Central Appalachia; and 4) foster and enhance a workforce characterized by diversity and inclusivity across all translational science disciplines and populations. The UK CTSA hub is uniquely positioned in the National CTSA Consortium to foster novel technologies, team science, clinical trial start-up and cutting-edge translational research across the lifespan with a focus on rural communities. We have a particular focus on the Central Appalachian community, a rural area with many of the highest levels of health disparities in the nation. This focus will ultimately elevate the health and quality of life of rural communities throughout the United States. Project Summary/Abstract Page 276 Contact PD/PI: Kern, Philip A.

联系PD/PI：Kern，Philip A. 项目摘要 - 总体 肯塔基大学（英国）临床与转化科学中心（CCTS）创建了一个 综合家庭进行临床和翻译研究，以促进科学进步和发现 翻译连续体的每个阶段。 CCT与阿巴拉契亚中部社区合作 解决与农村经济困扰有关的多代顽固的健康不平等 社区。 CCT从根本上改变了英国和阿巴拉契亚中部。 CTSA财团内的强大学术社区研究网络和合作。 阿片类药物和药物滥用流行病进一步放大了阿巴拉契亚的健康差异 极大地影响了肯塔基州东部和西弗吉尼亚州。强大的英国研究组合将英国CCT置于 领导地方，地区和国家研究工作的最佳立场集中在粗糙的健康不平等上。 英国，英国医疗保健和CCT的一致任务专注于通过参与来实现健康公平 高度创新，协作和动态的转化研究，以满足粗糙的健康需求。 CCT 将继续教育未来的转化劳动力，使农村社区参与转化和 双向团队科学并与国家网络合作，以推进跨学科研究和 通过以下特定目的进行临床试验：1）开发，创新和改变我们的研究环境 在我们的综合卫生保健系统中促进有影响力的科学和发现，以实现独特的健康 阿巴拉契亚中部居民的需求； 2）在提供有影响力的临床和 涵盖寿命，充分吸引社区并拥护团队科学的翻译研究； 3） 催化高效的大学范围临床试验组织，该组织为CTSA联盟增值 吸引来自阿巴拉契亚中部农村地区的参与者； 4）培养和增强以下特征的劳动力 所有转化科学学科和人群的多样性和包容性。英国CTSA枢纽是 独特地位于国家CTSA财团中，以促进新技术，团队科学，临床试验 整个生命周期的启动和尖端的翻译研究，重点是粗糙社区。我们 特别关注阿巴拉契亚中部社区，这是一个崎rough的地区 全国的健康差异。这种重点最终将提高农村的健康和生活质量 美国各地的社区。 项目摘要/摘要页面276 联系PD/PI：Kern，Philip A.