13th International Conference on Brain Energy Metabolism

第13届国际脑能量代谢会议

基本信息

批准号：
9544389
负责人：
MARY C MCKENNA
金额：
$ 1.5万
依托单位：
UNIVERSITY OF MARYLAND BALTIMORE
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-03-01 至 2019-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9544389
关键词：
Address Area Award Behavior Biology Brain Brain Diseases Chile Clinical Collaborations Communities Development Disease Energy Metabolism Epilepsy Evaluation Formulation Fostering Future Generations Geographic Distribution Glutamates Glutamine Goals Heterogeneity Homeostasis Image In Vitro International Ions Knowledge Learning Location Memory Metabolic Metabolism Mitochondria Nature Neurodegenerative Disorders Neuroglia Neurons Neurosciences Oxygen Participant Peer Review Physiology Postdoctoral Fellow Publishing Recording of previous events Regulation Research Research Personnel Role Scientist Series Signal Transduction South America Specialist Stroke Structure Students Techniques Time Tissues Travel Underrepresented Minority Woman aerobic glycolysis base behavior influence biochemical tools brain cell brain tissue clinically relevant collaborative environment driving force experimental study gamma-Aminobutyric Acid imaging genetics in vivo intercellular communication learned behavior meetings memory process minority scientist mitochondrial metabolism nervous system disorder neurological recovery neurotransmission new technology novel novel strategies programs symposium tool trafficking translational study web page

项目摘要

The 13th International Conference on Brain Energy Metabolism (ICBEM): "How Metabolism Dictates Neurotransmission, Function and Behavior" will be held on March 7-10, 2018, at the Centro de Estudios Científicos CECs, Valdivia, Chile. The field of brain energy metabolism is moving fast, propelled by new findings and rapidly developing new technologies that allow us to ask questions that could not be asked before about metabolism at cellular and subcellular levels in vitro and in vivo. Powerful imaging, genetic and biochemical tools are being used to characterize metabolism at tissue and cellular levels. Alterations in energy metabolism are a key underlying feature in stroke, epilepsy and in most, if not all, neurodegenerative diseases. However, little is known regarding causes and mechanisms, and interactions between poorly-understood, critical aspects of energy metabolism, a knowledge gap partly explained by the metabolic heterogeneity of brain tissue. The goal of 13th ICBEM meeting, which will be held for the first time in South America, is to bring together leading experts in these emerging techniques and researchers in clinical and basic neuroscience, physiology and learning and behavior who would not otherwise meet, and to serve as a driving force for cutting-edge discussions, formulation of incisive experiments, and for fostering collaborations that open novel areas of exploration of energy metabolism that underlie and contribute to brain diseases. This goal will be achieved by a small, focused conference (100-120 attendees), that includes a keynote talk on the hot subject of aerobic glycolysis and 24 invited speakers in eight scientific sessions. The conference brings together experts as well as students, postdocs and young investigators in a highly interactive forum with 33% of the meeting time allocated for discussion. Such interaction is needed to facilitate progress in this field of research and there are no other meetings of this nature that can facilitate this kind of interaction. Sessions address how mitochondrial biology and trafficking influence mitochondrial metabolism; neuroglial intercellular communication and tissue plasticity; oxygen and metabolite dynamics and sensing by neurons and glial cells; and the novel notion that energy is not just a permissive factor but is a driver for neurotransmission, memory processing and behavior. Student-fellow presentations are a key aspect of the meeting and an effective tool to help bring a new generation of scientists into our community and foster their maturation by inclusion as speakers and session co-chairs. Four young investigators are invited speakers, 20 students/postdocs will be awarded travel stipends based on competitive ranking of abstracts and geographic distribution, and ten students/postdocs selected by an evaluation committee will present short talks. This meeting will provide an outstanding venue for cross disciplinary interactions, i.e. between imaging specialists, basic neuroscientists and clinicians. Formal presentations and informal discussions are highlights of this unique conference series that fosters long-term scientific interactions to address emerging issues, and publishes a peer-reviewed special issue.

第13届国际脑能量代谢会议（ICBEM）：“代谢如何决定神经传递、功能和行为”将于 2018 年 3 月 7 日至 10 日在 Centro de Estudios 举行 Científicos CECs，瓦尔迪维亚，智利在新的推动下，大脑能量代谢领域正在快速发展。发现和快速发展的新技术使我们能够提出以前无法提出的问题关于体外和体内细胞和亚细胞水平的代谢的强大成像、遗传和代谢。生化工具被用来表征组织和细胞水平的代谢变化。新陈代谢是中风、癫痫和大多数（如果不是全部）神经退行性疾病的一个关键潜在特征。然而，人们对原因和机制以及知之甚少的之间的相互作用知之甚少。能量代谢的关键方面，知识差距部分由代谢异质性解释第 13 届 ICBEM 会议将首次在南美洲举行，其目标是这些新兴技术的领先专家以及临床和基础神经科学的研究人员，生理学、学习和行为否则不会相遇，并作为驱动力前沿的讨论、深入的实验的制定以及促进开启新颖的合作这一目标将是探索导致脑疾病的能量代谢领域。通过小型、集中的会议（100-120 名与会者）实现，其中包括关于热门主题的主题演讲会议汇集了有氧糖酵解的相关知识和 24 名受邀演讲者在八场科学会议上的发言。专家以及学生、博士后和年轻研究人员参加了一个高度互动的论坛，其中 33% 需要分配用于讨论的会议时间来促进该研究领域的进展。并且没有其他这种性质的会议可以促进这种互动，讨论如何进行。线粒体生物学和运输影响线粒体代谢；神经胶质细胞间通讯；组织可塑性；神经元和神经胶质细胞的氧和代谢动力学以及传感；能量不仅是一种许可因素，而且是神经传递、记忆处理和学生同学的演讲是会议的一个关键方面，也是帮助会议取得成果的有效工具。新一代科学家进入我们的社区，并通过作为演讲者和促进他们的成熟会议联合主席将受邀演讲，20 名学生/博士后将获得旅行费。基于摘要竞争排名和地理分布的津贴，以及十名学生/博士后由评估委员会选出的将进行简短的演讲。跨学科互动，即影像专家、基础神经科学家和精英之间的互动。演讲和非正式讨论是这一独特会议系列的亮点，旨在促进长期科学互动以解决新出现的问题，并出版同行评审的特刊。