11th International Conference on Brain Energy Metabolism

第十一届国际脑能量代谢会议

• 批准号: 8720381
• 负责人: MARY C MCKENNA
• 金额: $ 2万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8720381
• 关键词: Address; Aging; Area; Astrocytes; Award; Brain; Brain Diseases; Branched-Chain Amino Acids; Cell physiology; Cerebrum; Citric Acid Cycle; Clinical; Clinical Pathology; Coffee; Collaborations; Communities; Denmark; Development; Diabetes Mellitus; Disease; Drug Formulations; Energy Metabolism; Ensure; Environment; Evaluation; Fostering; Future; Generations; Geographic Distribution; Glucose; Glycogen; Goals; Homeostasis; International; Ion Transport; Ions; Journals; Location; Lymphatic System; Metabolism; Mitochondria; Nerve Degeneration; Neurons; Neurosciences; Oligodendroglia; Participant; Pathology; Peer Review; Postdoctoral Fellow; Reaction; Recording of previous events; Research; Research Personnel; Role; Scientist; Series; Signal Pathway; Signal Transduction; Structure; Students; Study Subject; Time; Traumatic Brain Injury; Travel; Underrepresented Minority; Woman; Work; abstracting; aging brain; base; brain metabolism; brain shape; clinically relevant; driving force; healthy aging; intercellular communication; interest; meetings; nervous system disorder; novel; novel strategies; posters; programs; public health relevance; relating to nervous system; research study; symposium; tool; translational study; web page

DESCRIPTION (provided by applicant): The 11th International Conference on Brain Energy Metabolism entitled "How Energy Metabolism Shapes Brain Function" will be held on May 11-14, 2014 at a conference center near Copenhagen, Denmark. This conference focuses on interactions between poorly-understood, critical aspects of energy metabolism and brain function, that include ion homeostasis and transport, roles of branched chain amino acids and glycogen, intracellular signaling, mitochondrial TCA cycle fluxes, and intercellular communication. Special-interest topics include, (I) oligodendrocyte metabolism and its abnormalities, which is an under-studied subject that is fundamental for brain function, (ii) novel contributions of glucose to neural pathology, and (iii) clinical aspects of brain metabolism in healthy aging and neurodegeneration. The reactions, fluxes, transporters, roles of signaling pathways in metabolism, interactions, and interactions between neurons, astroglia and oligodendroglia are still not adequately understood by neuroscientists in spite of their central importance to cellular function and disease. The major goal of this conference is, and has historically been, to serve as a driving force for cutting-edge discussions and formulation of incisive experiments, and for collaborations that open new areas of exploration of energy metabolism that underlie and contribute to brain diseases, including diabetes, aging, and traumatic brain injury. This goal will be achieved by a small, focused conference (about 100-120 attendees) that centers on brain energy metabolism and brings together the world's experts, students, and fellows who have a keen interest in this field. The program includes a keynote talk on the novel potential effects of a cerebral lymphatic system on energy metabolism and 32 invited speakers in eight scientific sessions on topics that focus on specific aspects of the continuum from interrelationships between transport and brain metabolism to the role of glucose in neural pathology, and aging and brain energy metabolism. Speakers include established experts and young investigators, with about 30% of the meeting time allocated for speaker-conferee discussions. Student-fellow presentations are an important aspect of the meeting and they are an effective tool to help bring a new generation of scientists into our community and foster their maturation by their inclusion as young investigator speakers and session chairs. Several young investigators are on the program as speakers. In addition, fifteen students/postdocs will be awarded travel stipends based on competitive ranking of their abstracts, as well as geographic distribution and ten young investigators selected by an evaluation committee will present talks in the poster-discussion session. Dedicated poster session time is enhanced by holding all coffee and refreshment breaks in the poster room to ensure informal discussions among conferees. Formal presentations and informal discussions among conferees are highlights of this unique conference series that fosters long-term scientific interactions to address emerging issues, and disseminates original research work and review articles by the conferees in a peer-reviewed special issue of a scientific journal.

描述（由申请人提供）：题为“能量代谢如何塑造大脑功能”的第 11 届国际脑能量代谢会议将于 2014 年 5 月 11 日至 14 日在丹麦哥本哈根附近的会议中心举行。本次会议重点关注能量代谢和脑功能的鲜为人知的关键方面之间的相互作用，包括离子稳态和运输、支链氨基酸和糖原的作用、细胞内信号传导、线粒体 TCA 循环通量和细胞间通讯。特别感兴趣的主题包括，(I) 少突胶质细胞代谢及其异常，这是一个尚未充分研究的课题，对大脑功能至关重要，(ii) 新颖的 葡萄糖对神经病理学的贡献，以及（iii）健康衰老和神经变性中脑代谢的临床方面。尽管反应、通量、转运蛋白、信号通路在新陈代谢中的作用、相互作用以及神经元、星形胶质细胞和少突胶质细胞之间的相互作用，尽管它们对细胞功能和疾病至关重要，但神经科学家仍未充分了解它们。这次会议的主要目标是，并且历来都是，作为前沿讨论和深入实验制定的驱动力，并为合作开辟新的探索领域的合作，能量代谢是脑疾病的基础和促成因素，包括糖尿病、衰老和脑外伤。这一目标将通过一次小型、集中的会议（约 100-120 名与会者）来实现，该会议以大脑能量代谢为中心，汇集了世界各地对此领域有浓厚兴趣的专家、学生和研究员。该计划包括关于脑淋巴系统对能量代谢的新的潜在影响的主题演讲，以及八场科学会议中的 32 名受邀演讲者，主题重点关注从运输和脑代谢之间的相互关系到葡萄糖在能量代谢中的作用等连续体的特定方面。神经病理学、衰老和脑能量代谢。演讲者包括知名专家和年轻研究者，约 30% 的会议时间用于演讲者与与会者的讨论。学生同事的演讲是会议的一个重要方面，它们是一个有效的工具，可以帮助将新一代科学家带入我们的社区，并通过让他们作为年轻研究者的演讲者和会议主席来促进他们的成熟。几位年轻的研究人员在该节目中担任演讲者。此外，十五名学生/博士后将根据其摘要的竞争排名以及地理分布获得旅行津贴，评估委员会选出的十名年轻研究者将在海报讨论会上发表演讲。通过在海报室举行所有咖啡和茶点休息时间，以确保与会者之间进行非正式讨论，可以增加专门的海报会议时间。与会者之间的正式演讲和非正式讨论是这一独特会议系列的亮点，该系列会议促进了长期的科学互动，以解决新出现的问题，并在同行评审的科学期刊特刊中传播与会者的原创研究工作和评论文章。