11th International Conference on Brain Energy Metabolism

第十一届国际脑能量代谢会议

• 批准号: 8720381
• 负责人: MARY C MCKENNA
• 金额: $ 2万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8720381
• 关键词: Address; Aging; Area; Astrocytes; Award; Brain; Brain Diseases; Branched-Chain Amino Acids; Cell physiology; Cerebrum; Citric Acid Cycle; Clinical; Clinical Pathology; Coffee; Collaborations; Communities; Denmark; Development; Diabetes Mellitus; Disease; Drug Formulations; Energy Metabolism; Ensure; Environment; Evaluation; Fostering; Future; Generations; Geographic Distribution; Glucose; Glycogen; Goals; Homeostasis; International; Ion Transport; Ions; Journals; Location; Lymphatic System; Metabolism; Mitochondria; Nerve Degeneration; Neurons; Neurosciences; Oligodendroglia; Participant; Pathology; Peer Review; Postdoctoral Fellow; Reaction; Recording of previous events; Research; Research Personnel; Role; Scientist; Series; Signal Pathway; Signal Transduction; Structure; Students; Study Subject; Time; Traumatic Brain Injury; Travel; Underrepresented Minority; Woman; Work; abstracting; aging brain; base; brain metabolism; brain shape; clinically relevant; driving force; healthy aging; intercellular communication; interest; meetings; nervous system disorder; novel; novel strategies; posters; programs; public health relevance; relating to nervous system; research study; symposium; tool; translational study; web page

DESCRIPTION (provided by applicant): The 11th International Conference on Brain Energy Metabolism entitled "How Energy Metabolism Shapes Brain Function" will be held on May 11-14, 2014 at a conference center near Copenhagen, Denmark. This conference focuses on interactions between poorly-understood, critical aspects of energy metabolism and brain function, that include ion homeostasis and transport, roles of branched chain amino acids and glycogen, intracellular signaling, mitochondrial TCA cycle fluxes, and intercellular communication. Special-interest topics include, (I) oligodendrocyte metabolism and its abnormalities, which is an under-studied subject that is fundamental for brain function, (ii) novel contributions of glucose to neural pathology, and (iii) clinical aspects of brain metabolism in healthy aging and neurodegeneration. The reactions, fluxes, transporters, roles of signaling pathways in metabolism, interactions, and interactions between neurons, astroglia and oligodendroglia are still not adequately understood by neuroscientists in spite of their central importance to cellular function and disease. The major goal of this conference is, and has historically been, to serve as a driving force for cutting-edge discussions and formulation of incisive experiments, and for collaborations that open new areas of exploration of energy metabolism that underlie and contribute to brain diseases, including diabetes, aging, and traumatic brain injury. This goal will be achieved by a small, focused conference (about 100-120 attendees) that centers on brain energy metabolism and brings together the world's experts, students, and fellows who have a keen interest in this field. The program includes a keynote talk on the novel potential effects of a cerebral lymphatic system on energy metabolism and 32 invited speakers in eight scientific sessions on topics that focus on specific aspects of the continuum from interrelationships between transport and brain metabolism to the role of glucose in neural pathology, and aging and brain energy metabolism. Speakers include established experts and young investigators, with about 30% of the meeting time allocated for speaker-conferee discussions. Student-fellow presentations are an important aspect of the meeting and they are an effective tool to help bring a new generation of scientists into our community and foster their maturation by their inclusion as young investigator speakers and session chairs. Several young investigators are on the program as speakers. In addition, fifteen students/postdocs will be awarded travel stipends based on competitive ranking of their abstracts, as well as geographic distribution and ten young investigators selected by an evaluation committee will present talks in the poster-discussion session. Dedicated poster session time is enhanced by holding all coffee and refreshment breaks in the poster room to ensure informal discussions among conferees. Formal presentations and informal discussions among conferees are highlights of this unique conference series that fosters long-term scientific interactions to address emerging issues, and disseminates original research work and review articles by the conferees in a peer-reviewed special issue of a scientific journal.

描述（由申请人提供）：第11届国际脑能源代谢会议题为“能源代谢如何塑造脑功能”将于2014年5月11日至14日在丹麦哥本哈根附近的会议中心举行。这次会议的重点是在不良理解，能量代谢的关键方面和大脑功能之间的相互作用，包括离子稳态和运输，分支链氨基酸的作用和糖原的作用，细胞内信号传导，线粒体TCA循环循环通量和细胞间通信。特殊利益的主题包括（i）少突胶质细胞代谢及其异常，这是一个对脑功能基础的研究不足的主题，（ii）新颖 葡萄糖对神经病理学的贡献以及（iii）健康衰老和神经变性中脑代谢的临床方面。神经科学家对神经科学家对细胞功能和疾病的重要性，仍然对神经元，星形胶质细胞和寡头胶质细胞之间的反应，信号通路在代谢中的作用，相互作用以及神经元之间的相互作用以及神经科学家之间的相互作用仍然没有充分理解。这次会议的主要目标是并且历史上一直是尖端讨论和敏锐实验的表述的推动力，以及为能源代谢探索新的新领域的合作，这些领域是基于脑部疾病的基础，包括糖尿病，衰老和脑部疾病。这一目标将由一个小的，重点的会议（约100-120名与会者）实现，该会议以大脑能源代谢为中心，并汇集了对这一领域兴趣浓厚的世界专家，学生和研究员。该计划包括一个主题演讲，讲述了脑淋巴系统对能量代谢的新潜在影响，并在八个科学会议中邀请了32位邀请演讲者对主题的介绍，这些主题着重于连续性的特定方面，这些方面是从运输和脑代谢之间的相互关系到葡萄糖在神经病理病理和脑部能量能量中的作用。演讲者包括知名专家和年轻的调查员，大约30％的会议时间分配给了演讲者征服者讨论。学生对学生的演讲是会议的重要方面，它们是一种有效的工具，可以帮助将新一代的科学家带入我们的社区，并通过将其作为年轻的调查员演讲者和会议主持人促进成熟。一些年轻的调查员正在该计划中担任演讲者。此外，将根据其摘要的竞争排名以及评估委员会选择的十名年轻调查员将在海报访问会议上介绍谈话，从而将15名学生/博士后授予旅行津贴。通过在海报室中握住所有咖啡和茶点休息，以确保同盟之间的非正式讨论，从而增加了专用的海报会议时间。同盟国之间的正式演讲和非正式讨论是这个独特的会议系列的亮点，该系列培养了长期的科学互动来解决新兴问题，并在同行评审的科学杂志的一期特刊中宣布了原始的研究工作和审查文章。