9th International Conference on Brain Energy Metabolism

第九届国际脑能量代谢会议

• 批准号: 7912757
• 负责人: MARY C MCKENNA
• 金额: $ 1.6万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-15 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7912757
• 关键词: Area; Astrocytes; Brain; Brain Diseases; Cell physiology; Cells; Collaborations; Communication; Communities; Cytosol; Degenerative Disorder; Diabetes Mellitus; Disease; Drug Formulations; Energy Metabolism; Ensure; Event; Failure; Fostering; Generations; Goals; Hour; Hungary; International; Journals; Knowledge; Laboratories; Metabolic; Mitochondria; Neurodegenerative Disorders; Neurons; Parkinson Disease; Pathogenesis; Peer Review; Production; Reaction; Research; Research Personnel; Scientist; Series; Signal Transduction; Speed; Stroke; Students; Time; Traumatic Brain Injury; Universities; Work; brain metabolism; driving force; improved; interest; meetings; nervous system disorder; posters; programs; public health relevance; research study; symposium; tool

DESCRIPTION (provided by applicant): The 9th International Conference on Brain Energy Metabolism entitled "Mitochondrial-Cytosolic Interactions: From Energetics to Pathogenesis" will be held on July 7-10, 2010, at Semmelweis University, Budapest, Hungary (http://www.icbem-budapest-2010.org/). The program includes two keynote speakers and 25 invited speakers in six scientific sessions on topics that focus on specific aspects of the continuum from mitochondrial energetics and brain metabolism to the relationships of energy failure to pathogenesis of neurological diseases. Speakers include established experts and young investigators, with about 30% of the time allocated to each session for speaker-conferee discussions. Student-fellow presentations are an important aspect of the meeting and they are an effective tool to help bring a new generation of scientists into our community and foster their maturation by their inclusion as young investigator speakers and session chairs. In addition, there are three poster sessions for a total of 7.5 hours to ensure plenty of informal discussion time with presentations by conferees. This conference focuses on intracellular communication between the cytosol and mitochondria, which is an under-studied topic that is critical for metabolic, biosynthetic, signaling, regulatory, and energetic aspects of neuronal and astrocytic function, as well as neuron-astrocyte interactions. The reactions, fluxes, transporters, and regulatory signaling aspects of cytosolic-mitochondrial interactions are poorly understood by neuroscientists in spite of their central importance to cellular function and disease. The major goal of this conference is, and has historically been, to serve as a driving force for cutting-edge discussions and formulation of incisive experiments and collaborations that open new areas of exploration of energy metabolism that underlie and contribute to brain diseases, including stroke, degenerative diseases, and traumatic brain injury. This goal will be achieved by a small, focused conference (about 100-120 attendees) that centers around brain energy metabolism and brings together the world's experts, students, and fellows who have a keen interest in this field. Formal presentations and informal discussions are highlights of this conference series that fosters long-term scientific interactions and disseminates original research work and review articles by the conferees in a peer-reviewed special issue of a scientific journal. PUBLIC HEALTH RELEVANCE: The Brain Energy Metabolism conference is a 4-day scientific educational event in which conference attendees will convey cutting-edge results of research related to brain diseases that involve energy production and mitochondria, the powerhouses of cells that generate most of the energy. Diseases such as stroke, diabetes, Parkinson's disease, and other neurodegenerative diseases all have serious disturbances of energy production as an underlying feature, and sharing knowledge with others improves research and speeds the transfer of potential treatments from the laboratory to bedside.

描述（由申请人提供）：第9届国际脑能量代谢会议标题为“线粒体 - 胞质相互作用：从能量到发病机理”将于2010年7月7日至10日在匈牙利布达佩斯郡的Semmelweis大学，匈牙利（http://wwwwwwwwww.icbem-budapest-2010.org/）举行。该计划包括两个主题演讲者和25位受邀演讲者，在六个科学会议上，介绍了关注从线粒体能量学和大脑代谢到能量失败到神经系统疾病发病机理的关系的连续体的特定方面。演讲者包括知名的专家和年轻调查员，大约有30％的时间分配给每个会议的演讲者讨论。学生对学生的演讲是会议的重要方面，它们是一种有效的工具，可以帮助将新一代的科学家带入我们的社区，并通过将其作为年轻的调查员演讲者和会议主持人促进成熟。此外，共有三个海报会议，总共7.5小时，以确保大量的非正式讨论时间，并通过Conderees的演讲。这次会议的重点是细胞质和线粒体之间的细胞内沟通，这是一个研究不足的话题，对于神经元和星形细胞功能的代谢，生物合成，信号，调节，调节和能量方面至关重要，以及神经元 - 腹细胞相互作用。尽管神经科学家对细胞功能和疾病的重要性非常重要，但神经科学家的反应，转运蛋白和调节信号传导方面还是很少了解神经科学家。这次会议的主要目标是并且历史上一直是尖端讨论和敏锐的实验和协作的驱动力，这些实验和合作开放了能量代谢的新领域，这些领域是基于中风，退化性疾病，脑部疾病，以及脑部疾病的基础，并为脑部疾病做出了贡献。这一目标将通过一个小的，重点的会议（约100-120名与会者）实现，该会议以脑能量代谢为中心，并将对这一领域感兴趣的世界专家，学生和研究员汇集在一起​​。正式的演讲和非正式讨论是该会议系列的亮点，该系列培养了长期的科学互动，并在同行评审的科学杂志的特刊中传播了Conferees的原始研究工作和审查文章。 公共卫生相关性：大脑能源代谢会议是为期4天的科学教育活动，会议参与者将传达与涉及能量生产和线粒体的脑疾病有关的研究结果，这些研究结果是能源生产和线粒体，这是产生大部分能量的细胞的动力。诸如中风，糖尿病，帕金森氏病和其他神经退行性疾病之类的疾病都对能源生产作为基本特征的障碍都严重干扰，并且与他人共享知识可以改善研究并加快从实验室到床边的潜在治疗方法的转移。